Results 41 to 50 of about 1,737,552 (105)
Nucleosome-mediated cooperativity between transcription factors [PDF]
Cooperative binding of transcription factors (TFs) to cis-regulatory regions (CRRs) is essential for precision of gene expression in development and other processes. The classical model of cooperativity requires direct interactions between TFs, thus constraining the arrangement of TFs sites in a CRR.
arxiv +1 more source
A PMUT Integrated Microfluidic System for Fluid Density Sensing [PDF]
We demonstrate the design, fabrication and use of a dual electrode PMUT (Piezoelectric Micromachined Ultrasound Transducer) integrated with a microfluidic channel as a fluid density sensor in both static and dynamic density-change conditions. The dual electrode configuration makes the PMUT resonator a self-contained resonant peak-shift sensor and the ...
arxiv
1. A family is reported in which 2 children have unmistakable sickle cell anemia, but the mother’s red cells do not sickle; the father and a third child exhibit the typical sickle cell trait.
K. Singer, B. Fisher
semanticscholar +1 more source
Combining optical diffraction tomography with imaging flow cytometry for characterizing morphology, hemoglobin content, and membrane deformability of live red blood cells [PDF]
Integrating optical diffraction tomography with imaging flow cytometry enables label-free quantifications of the three-dimensional (3D) morphology and hemoglobin content of red blood cells (RBCs) in their natural form. Self-rotation of RBCs flowing in a microfluidic channel has been utilized to achieve various projection directions for 3D ...
arxiv
Human abnormal hemoglobins. 11. A chemical study of hemoglobin Lepore from a homozygote individual.
The hemoglobins of a child homozygous for the Lepore Boston gene have been analyzed. Only hemoglobin F and Lepore were observed. Hemoglobin Lepore was isolated and the peptide chains of this hemoglobin were separated.
C. Baglioni, V. Ventruto
semanticscholar +1 more source
Hb Andrew-Minneapolis Variant in a Turkish Family
Hamza Sümter+3 more
doaj +1 more source
Background: Brazil has a multiethnic population with a high diversity of hemoglobinopathies. While screenings for beta-globin mutations are far more common, alterations affecting alpha-globin genes are usually more silent and less well known.
Elza Miyuki Kimura+9 more
doaj +1 more source
α-Thalassemia impairs the cytoadherence of Plasmodium falciparum-infected erythrocytes. [PDF]
α-Thalassemia results from decreased production of α-globin chains that make up part of hemoglobin tetramers (Hb; α(2)β(2)) and affects up to 50% of individuals in some regions of sub-Saharan Africa.
Michael A Krause+10 more
doaj +1 more source
Comment on "Twisted Protein Aggregates and Disease: The Stability of Sickle Hemoglobin Fibers" [PDF]
Aggregates of twisted protein fibers, such as sickle hemoglobin and actin, are important examples of biopolymers in which elastic interactions play a crucial role in determining the (metastable) bundle radii. Here, we present a corrected version of analysis on the stability of sickle hemoglobin fibers using the classic nucleation theory.
arxiv
Localised IR spectroscopy of hemoglobin [PDF]
IR absorption spectroscopy of hemoglobin was performed using an IR optical parametric oscillator laser and a commercial atomic force microscope in a novel experimental arrangement based on the use of a bottom-up excitation alignment. This experimental approach enables detection of protein samples with a resolution that is much higher than that of ...
arxiv