Results 211 to 220 of about 86,632 (376)
Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe+4 more
wiley +1 more source
Precise Engineering and Efficient Biosynthesis of Robust and High-Activity Human Haemoglobin for Artificial Oxygen Carriers. [PDF]
Liu F+5 more
europepmc +1 more source
On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley +1 more source
Concentração de hemoglobina em crianças do nascimento até um ano de vida
Este estudo foi desenvolvido com o objetivo de descrever a evolução da concentração de hemoglobina [Hb], considerando os fatores: peso ao nascer; velocidade relativa de crescimento e alimentação. É um estudo transversal realizado com crianças no primeiro
Sophia Cornbluth Szarfarc+7 more
doaj
Hemoglobin phenotypes of children attending pediatric clinics in Lomé, Togo, 2022. [PDF]
Konu YR+9 more
europepmc +1 more source
Antibody Response to Hemoglobin Adsorbed on Aluminum Hydroxide [PDF]
Frances E. Holford+2 more
openalex +1 more source
The present study constructs machine‐learning models to resolve developmental relationships among auditory performance, auditory cortical processing, and functional connectivity of the bilateral language network during the first year of restored hearing. The results demonstrate that asymmetric inter‐hemisphere communication contributes significantly to
Xue Zhao+6 more
wiley +1 more source
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao+14 more
wiley +1 more source