Results 241 to 250 of about 362,737 (351)

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

In vitro-induced Heinz bodies showed no impact on feline reticulocyte haemoglobin content measurement using the Advia 2120i analyser. [PDF]

J Feline Med Surg
Jensen AL, Vestergaard JD, Nielsen LN, Krogh AK, Langhorn R.   +4 more
europepmc   +1 more source

Hydrogen‐Producing Catalysts Based on Ferredoxin Scaffolds

Advanced Science, EarlyView.
Selected plant‐type ferredoxins that lack their natural [2Fe‐2S] clusters functionally bind a hydrogenase active site cofactor and act as hydrogenases themselves. In combination with photosystem I, the light‐dependent H₂ evolution almost matches the H₂ production rates of the natural system.
Yiting She, Vera Engelbrecht, Jacek Kozuch, Ulf‐Peter Apfel, Sven T. Stripp, Anja Hemschemeier, Thomas Happe   +6 more
wiley   +1 more source

Preoperative Anemia Is an Independent Prognostic Factor for Esophageal Cancer Patients Who Receive Curative Treatment. [PDF]

In Vivo
Shimada K, Aoyama T, Hashimoto I, Maezawa Y, Esashi R, Fukuda M, Ju M, Yamamoto S, Kazama K, Kamiya N, Okuda N, Tamagawa A, Numata K, Uchiyama M, Saito A, Yukawa N.   +15 more
europepmc   +1 more source

Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy

Advanced Science, EarlyView.
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao, Xianping Liu, Xu Chu, Feixiang Chen, Ruicheng Shi, Zonghao Liu, Yelin Wu, Yanyan Liu, Wenbo Bu   +8 more
wiley   +1 more source

Comparison of different testosterone formulations discontinuation and dose spacing on hematocrit and testosterone levels in transgender individuals with erythrocytosis. [PDF]

Rev Bras Ginecol Obstet
Okano SHP, Franceschini SA, Brito LGO, Lara LADS.   +3 more
europepmc   +1 more source

A Complementarity‐Based Approach to De Novo Binder Design

Advanced Science, EarlyView.
A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko, Valeriia Hatskovska, Murray Coles, Narges Aghaallaei, Natalia Pashkovskaia, Natalia Borbarán‐Bravo, Matteo Pilz, Philip Bucher, Mareike Volz, Joana Pereira, Marcus D. Hartmann, Ghazaleh Tabatabai, Judith Feucht, Stefan Liebau, Patrick Müller, Andrei N. Lupas, Julia Skokowa, Mohammad ElGamacy   +17 more
wiley   +1 more source

Utilizing loop-mediated isothermal amplification (LAMP) for detecting hemoglobin Constant Spring and hemoglobin Pakse mutations amidst the high prevalence and genetic heterogeneity of thalassemia in Thailand. [PDF]

PeerJ
Wongprachum K, Thitipoomdecha N, Ananratanakit P, Prakobkul W, Angkuranak U, Sawangkul N, Panichchob P, Karnpean R, Jomoui W.   +8 more
europepmc   +1 more source

The Probiotic Parabacteroides johnsonii Ameliorates Metabolic Disorders Through Promoting BCAAs to BSCFAs Conversion

Advanced Science, EarlyView.
Clinical discovery and the proposed underlying mechanism by how P. johnsonii ameliorated metabolic disorders. Abstract The gut bacterium Parabacteroides spp. is increasingly recognized for its therapeutic potential in treating metabolic disorders. However, the role of Parabacteroides johnsonii in metabolic disorders is never reported.
Yimeng Chen, Shujun Jiang, Haolu Wang, Mengzhen Si, Haixia Wu, Xinyi Liang, Shenmeng Yao, Yanliang Zhang, Xiaodong Wen, Jie Yang   +9 more
wiley   +1 more source

Evaluation of Intraoperative and Postoperative Blood Cell Salvage Use in Cardiac Surgery with Cardiopulmonary Bypass. [PDF]

Braz J Cardiovasc Surg
Mello MAA, Pereira-Rufino LDS, Santos AAD, Hossne NA, Panfilio CE, Souza AS, Céspedes IC.   +6 more
europepmc   +1 more source