Results 261 to 270 of about 88,647 (334)

Lenvatinib Plus Paclitaxel as Second‐Line Therapy for Advanced Gastric Cancer Patients: A Dose Escalation Exploratory Study

Advanced Science, EarlyView.
This study determines the maximum tolerated dose of lenvatinib in combination with paclitaxel as second‐line therapy for advanced gastric cancer patients. A dynamic network biomarker panel associated with patient prognosis and response to treatment is established.
Chenfei Zhou, Jinling Jiang, Liting Guo, Wenqi Xi, Junwei Wu, Qu Cai, Jun Ji, Feng Qi, Jun Zhang   +8 more
wiley   +1 more source

Safety and effectiveness of iron sucrose therapy in paediatric patients with iron deficiency anaemia: a single-institution retrospective study. [PDF]

BMC Pediatr
Zhao S, Cheng J, Zhang L, Yao J, Jiang J.   +4 more
europepmc   +1 more source

HEMOGLOBIN SYNTHESIS FROM GLYCINE LABELED WITH RADIOACTIVE CARBON IN ITS α-CARBON ATOM

, 1948
Kurt I. Altman, George W. Casarett, Raymond E. Masters, Thomas R. Noonan, K. Salomon   +4 more
openalex   +1 more source

ACSS2/AATF Drives Soluble FasL‐Mediated CD8+ T Cell Apoptosis in Pancreatic Neuroendocrine Tumors

Advanced Science, EarlyView.
This study unveils that ACSS2‐driven acetate metabolism fuels histone pan‐acetylation in pancreatic neuroendocrine tumors (PNETs), remodeling the epigenetic landscape. The ACSS2/AATF axis transcriptionally activates soluble FasL (sFasL), which engages Fas receptors on infiltrating CD8+ T cells to trigger caspase‐8/3‐mediated apoptosis.
Qin Dang, Ting Wang, Yan Wang, Zeng Ye, Borui Li, Xuan Pan, Zheng Li, Guixiong Fan, Desheng Jing, Junfeng Xu, Qiangsheng Hu, Shunrong Ji, Xiaowu Xu, Xianjun Yu, Yi Qin   +14 more
wiley   +1 more source

Metabolic Signatures in Lung Cancer: Prognostic Value of Acid-Base Disruptions and Serum Indices. [PDF]

Int J Mol Sci
Ponholzer F, Neuschmid MC, Komi H, Bogensperger C, Ng C, Maier H, Lucciarini P, Schneeberger S, Augustin F.   +8 more
europepmc   +1 more source

DETERMINATION OF CARBON MONOXIDE IN BLOOD AND OF TOTAL AND ACTIVE HEMOGLOBIN BY CARBON MONOXIDE CAPACITY. INACTIVE HEMOGLOBIN AND METHEMOGLOBIN CONTENTS OF NORMAL HUMAN BLOOD

, 1946
Donald D. Van Slyke, Alma Hiller, James R. Weisiger, W. O. Cruz   +3 more
openalex   +1 more source

AI‐Driven De Novo Design of Ultra Long‐Acting GLP‐1 Receptor Agonists

Advanced Science, EarlyView.
De novo GLP‐1RAs can be computationally designed to exhibit extended half‐life and superior efficacy compared to Semaglutide. Abstract Peptide drugs have revolutionized modern therapeutics, offering novel treatment avenues for various diseases. Nevertheless, low design efficacy, time consumption, and high cost still hinder peptide drug design and ...
Ting Wei, Jiating Ma, Xiaochen Cui, Jiahui Lin, Zhuoqi Zheng, Liu Cheng, Taiying Cui, Xiaoqian Lin, Junjie Zhu, Xuyang Ran, Xiaokun Hong, Luke Johnston, Zhangsheng Yu, Haifeng Chen   +13 more
wiley   +1 more source

GLP-1 analog therapy and hemoglobin levels: Insights from a retrospective study. [PDF]

Saudi Med J
Almuammar SA, Alzahrani HK.
europepmc   +1 more source

Inverse Co‐Design of Mechanical And Sensory Properties in Soft Lattice Foams for Multifunctional Wearables

Advanced Science, EarlyView.
An inverse co‐design framework integrates neural networks and physics‐based models to engineer soft lattice foams with independently tunable mechanical and sensory properties. By layering architected foams and optimizing electrode placement, this method enables multifunctional wearable sensors.
Qinghua Guan, Benhui Dai, Harshal Sonar, Josie Hughes   +3 more
wiley   +1 more source

Changes in body composition and their association with erythrocyte mass in regular exercisers: A cross-sectional study. [PDF]

Medicine (Baltimore)
Demircioğlu S, Tekinalp A, Korkmaz C, Alkan Baylan F, Merter M.   +4 more
europepmc   +1 more source