Results 271 to 280 of about 86,632 (376)

Reinforced Granular Hydrogels Scaffolds with Tunable Physicochemical Properties for Advanced Skin Tissue Engineering

Advanced Science, EarlyView.
This work introduces a highly customizable granular hydrogel scaffold, designed from reactive microparticles through binary macromonomer microdroplet assembly, achieving a precise balance of mechanical strength and biological functionality. Abstract Engineering bioscaffolds with tailored architectures and optimized physicochemical properties remains a ...
Jing Zhang, Yijia Wang, Yue Liu, Guanfu Wu, Guilong Lu, Yue Li, Yu Shen, Caifeng Wang, Mehdi Khanmohammadi, Wojciech Święszkowski, Jing Wang, Ziyi Yu   +11 more
wiley   +1 more source

Red cell mass measurement is still useful for the management of myeloproliferative neoplasms. Comment to "Role of red cell mass evaluation in myeloproliferative neoplasms with splanchnic vein thrombosis and normal hemoglobin value: a study of the France Intergroupe des Syndromes Myeloprolifératifs". [PDF]

Haematologica
Maaziz N, Girodon F.
europepmc   +1 more source

ON THE STRUCTURE OF PROTEINS: CATTLE HEMOGLOBIN, EGG ALBUMIN, CATTLE FIBRIN, AND GELATIN

, 1937
Max Bergmann, Carl Niemann
openalex   +1 more source

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Advanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu, Min Feng, Yi Chen, Hong‐Lin Jia, Qi Zhang, Ming Tong, Yan‐Xi Li, Yu Zhao, Xin‐Xin Liu, Shi‐Feng Cao, Zheng‐kai Wang, Hou‐wei Li, Xue Liu, Yan Zhang   +13 more
wiley   +1 more source

Base editing HbS to HbG-Makassar improves hemoglobin function supporting its use in sickle cell disease. [PDF]

Nat Commun
Kostamo Z, Ortega MA, Xu C, Feliciano PR, Budak E, Lam D, Winton V, Jenkins R, Venugopal A, Zhang M, Jamieson J, Coisman B, Goldsborough K, Hernandez B, Kanne CK, Evans EN, Zgodny J, Zhang Y, Darazim J, Patel A, Pendergast MA, Manis J, Hartigan AJ, Ciaramella G, Lee SJ, Chu SH, Sheehan VA.   +26 more
europepmc   +1 more source

RATIO OF SICKLE-CELL ANEMIA HEMOGLOBIN TO NORMAL HEMOGLOBIN IN SICKLEMICS

, 1951
Ibert C. Wells, Harvey A. Itano
openalex   +1 more source

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

Advanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao, Yijia Yin, Fangyuan Shuai, Waishan Lam, Tao Zhou, Yaxin Xie, Xuesong He, Xianglong Han   +7 more
wiley   +1 more source

Rapid preparation of bioactive composites for transforaminal lumbar interbody fusion. [PDF]

Sci Rep
Ding B, Wang X, Zhao C, Zhao J.
europepmc   +1 more source

Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure‐Based Virtual Screening

Advanced Science, EarlyView.
Pancreatic cancer is a highly aggressive malignancy with limited treatment options. CLK4 regulates alternative splicing, contributing to cancer progression. This study establishes a computational model to identify CLK4 inhibitors, leading to compound 150441 (IC50: 21.4 nm).
Chun‐Lin Yang, Yi‐Wen Wu, Huang‐Ju Tu, Yun‐Hsuan Yeh, Tony Eight Lin, Tzu‐Ying Sung, Mu‐Chun Li, Shih‐Chung Yen, Jui‐Hua Hsieh, Ming‐Chin Yu, Sen‐Yung Hsieh, Hsing‐Pang Hsieh, Shiow‐Lin Pan, Kai‐Cheng Hsu   +13 more
wiley   +1 more source

Wandering about allostery. [PDF]

Biol Direct
Brunori M.
europepmc   +1 more source