Results 291 to 300 of about 90,177 (337)

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

Erythrocyte lifespan for predicting moderate and severe anemia in advanced gastric cancer patients post-anti-tumor therapeutics: a prospective study. [PDF]

BMC Cancer
Yu X, Su L, Lu R, Zhao S, Lin R, Ye X.
europepmc   +1 more source

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

Advanced Science, EarlyView.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang, Kanella M. Cohen, Liqiang Chen, Xiaowo Kang, Chang Liu, Megan E. Demouth, Wenxia Jiang, Alexander R. Maldeney, Rong Tong, Zunlong Ke, Kartik Chandran, Wei Luo, Qian Yin   +12 more
wiley   +1 more source

High-Oxygen-Affinity Hemoglobins-Case Series and Review of the Literature. [PDF]

J Clin Med
Komninaka V, Flevari P, Ntelaki EE, Yfanti E, Androutsakos T, Ntanasis-Stathopoulos I, Terpos E.   +6 more
europepmc   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Metabolic engineering of yeast to efficiently synthesize heme and hemoproteins: recent advance and prospects. [PDF]

FEMS Yeast Res
Yu H, Wang Y, Wang Y, Niu Y, Zhou J, Li J, Chen J, Du G, Zhao X.   +8 more
europepmc   +1 more source

A retrospective analysis of clinical characteristics and risk factors of renal anemia in elderly patients on maintenance hemodialysis. [PDF]

Medicine (Baltimore)
Juan L, Wei L.
europepmc   +1 more source

Effects of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors on Relationship Between B-Type Natriuretic Peptide and Hemoglobin Levels in Patients With Cardiorenal Anemia Syndrome. [PDF]

Cardiovasc Ther
Yoshitake T, Hashimoto T, Matsushima S, Ikuta K, Yamamoto S, Suenaga T, Nakashima S, Kai T, Misumi K, Shinohara K, Fujino T, Katsuki S, Hosokawa K, Kinugawa S, Abe K.   +14 more
europepmc   +1 more source

Reference Intervals for Research Parameters of Reticulocyte Hemoglobin and Platelet Clumps in Healthy Korean Adults

Miyoung Kim, Sangkyoon Hong, Nan Young Kim, Kibum Jeon, Jiwon Lee, Han-Sung Kim, Hee Jung Kang, Young Kyung Lee   +7 more
openalex   +2 more sources

Mechanisms of Globin Gene Regulation in Mammals. [PDF]

Annu Rev Genet
Hardison RC.
europepmc   +1 more source