Results 41 to 50 of about 26,824 (289)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Are sex differences in blood cell count and hemoglobin moderated by the 2D:4D ratio? A cross‐sectional study in a Ghanaian population

Health Science Reports, 2023
Background and Aims There are sex differences in blood cell count and hemoglobin (HGB) in adulthood due to differences in the levels of circulating sex hormones. The second‐to‐fourth digit ratio (2D:4D) is the putative marker of prenatal hormone exposure.
Moses Banyeh, Thea Kangkpi, Simon B. Bani, Kervin Edinam Zogli, Muniru Mohammed Tanko, Peter Eugene Atuahene, Aisha Yaaba Iddrisu, Christine Ekor, Emmanuel Osei Akoto, Nafiu Amidu   +9 more
doaj   +1 more source

Tertiary conformational transition constant of guinea pig haemoglobin determined from the reaction of 5,5′-dithiobis (2-nitrobenzoate) with CysF9[93]β and CysH3[125]β [PDF]

, 2013
We have determined Kequ, the equilibrium constant for the reaction of 5,5′-dithiobis(2-nitrobenzoate) — DTNB — with the CysF9*93+β and CysH3*125+β sulphydryl groups of various derivatives of guinea pig haemoglobin at 25oC.
Adeogun, I. A., Okonjo, K. O., Yusuff, O.   +2 more
core   +1 more source

Anisotropic coarse-grained statistical potentials improve the ability to identify native-like protein structures [PDF]

, 2003
We present a new method to extract distance and orientation dependent potentials between amino acid side chains using a database of protein structures and the standard Boltzmann device.
Bagci, Bahar, Banavar, Ben-Naim, Berman, Betancourt, D. Thirumalai, Dima, Duan, Eisenberg, Ferrara, Fiebig, Gatchell, Gay, Godzik, Hendlich, Humphrey, J. E. Straub, Keskin, Kussell, Lee, Lee, Lee, Levitt, Liwo, Liwo, Liwo, Meller, Meller, Miyazawa, N.-V. Buchete, Plaxco, Richards, Samudrala, Samudrala, Shen, Sippl, Sippl, Soyer, Steinhardt, Tanaka, ten Wolde, ten Wolde, Thomas, Tobi, Tobi, Tsai, van Duijneveldt, Vendruscolo, Vorobjev, Vorobjev   +50 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Neocytolysis: How to Get Rid of the Extra Erythrocytes Formed by Stress Erythropoiesis Upon Descent From High Altitude

Frontiers in Physiology, 2018
Neocytolysis is the selective destruction of those erythrocytes that had been formed during stress-erythropoiesis in hypoxia in order to increase the oxygen transport capacity of blood.
Heimo Mairbäurl
doaj   +1 more source

Hemoglobin genotype has minimal influence on the physiological response of juvenile atlantic cod (Gadus morhua) to environmental challenges

, 2009
Hemoglobin (Hb) polymorphism in cod is associated with temperature‐related differences in biogeographical distribution, and several authors have suggested that functional characteristics of the various hemoglobin isoforms (HbIs) directly influence ...
Afonso, L. O. B., Busby, C. D., Gamperl, A. K., Hall, J. R., Hori, T. S. F.   +4 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Determination of Beta Thalassemia trait and abnormal Hemoglobin variant frequency

Iberoamerican Journal of Medicine
Introduction: Hemoglobinopathies are among the most common hereditary disorders globally, classified into thalassemias and abnormal hemoglobins. Abnormal hemoglobins arise from genetic alterations like point mutations, insertions, or deletions, with Hb S,
Miraç Seher Helvacı, Melih Tekinay, Okan Yılmaz, Mustafa Şahin, Öngen İpek, Eren Vurgun, Okan Dikker, Hüseyin Dağ   +7 more
doaj   +1 more source

A comparative study of norethisterone and combined oral contraceptive pill in the treatment of dysfunctional uterine bleeding

CHRISMED Journal of Health and Research, 2019
Background: A significant percentage of women in India suffer from dysfunctional uterine bleeding (DUB), which has a negative impact on physical and social life.
Sayantan Sen, Tapan Kumar Mandal, Arijit Dutta, Himel Mondal, Tufan Khalua   +4 more
doaj   +1 more source