Results 61 to 70 of about 21,561 (293)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

EFFECT OF MODIFIED ULTRAFILTRATION ON HEMODYNAMICS IN PEDIATRIC CARDIAC SURGERY AT ARMED FORCES INSTITUTE OF CARDIOLOGY/ NATIONAL INSTITUTE OF HEART DISEASES (AFIC/NIHD)

Pakistan Armed Forces Medical Journal, 2020
Objective: To observe the effect of modified ultrafiltration on hemodynamics of pediatric patients. Study Design: A descriptive cross-sectional study. Place and Duration of Study: Pediatric Cardiac Surgery department, AFIC/NIHD Rawalpindi, from Jun
Muneeb Ur Rehman, Tariq Rao, Naila Niaz, Shahid Nafees, Naseem Azad, Muhammad Shoaib Umar   +5 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

The Effect of Hemoglobin and Body Mass Index on the Outcomes of COVID-19: A Prospective Cohort Study [PDF]

Journal of Community Health Research
Background: Previous studies indicated the risk factors for COVID-19. Malnutrition is one of the main causes of immune system failure. This study aims to investigate the effect of nutritional status on the outcomes of COVID-19 in participants of Yazd ...
Shirin Hasanizadeh, Hadis Varaee, Fatemeh Mirjalili, Azadeh Najarzadeh, Masoud Mirzaei   +4 more
doaj  

Deep Learning Model-Based Detection of Anemia from Conjunctiva Images [PDF]

Healthcare Informatics Research
Objectives Anemia is characterized by a reduction in red blood cells, leading to insufficient levels of hemoglobin, the molecule responsible for carrying oxygen.
Najmus Sehar, Nirmala Krishnamoorthi, C. Vinoth Kumar   +2 more
doaj   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Quantitation of hemoglobins by immunodiffusion: Specific antibodies to hemoglobins A1, S and F

, 1974
A simple and sensitive immunochemical method for quantifying hemoglobins A1, S and F is described. Antibodies to human hemoglobins A1, S and F were obtained in goats and after cross absorption were shown to be specific for thei corresponding hemoglobins.
E. Headings, Verle, Shukla, Suresh B.
core   +1 more source

Hemoglobins of the Cutthroat Trout \u3cem\u3eSalmo clarki\u3c/em\u3e [PDF]

, 1983
Nine hemoglobins have been isolated from the blood of cutthroat trout. All nine hemoglobins bind oxygen cooperatively and appear to be tetramers with molecular weights of -64,000.
Southard, Jonathan N.
core   +1 more source