Results 151 to 160 of about 116,124 (310)

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Evaluation of CFD based hemolysis prediction methods

, 2011
Accurate quantitative evaluation of shear stress-related hemolysis (destruction of red blood cells) could be used to improve blood handling devices, including left ventricular assist devices (LVAD).
Myagmar, Oyuna
core  

Dual‐Stage Microneedle Patch With Lipid Droplet‐Mediated ‘Capture‐Kill’ and Sustained Release for Enhanced Wound Healing

Advanced Science, EarlyView.
We report a lipid‐droplet‐engineered, gallium‐loaded sonodynamic therapeutic platform (LDTG) incorporated into a bilayer microneedle (MN) patch co‐delivering all‐trans retinoic acid (ATRA), termed LDTG A‐MNs, for synergistic antibacterial therapy and accelerated wound repair.
Peng Jiang, Meijun Jiang, Jiapeng Lei, Wen Zhang, Huiyuan Yang, Xueyang Wang, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

Advanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che, Donghong Li, Huan Zhang, Tingting Xu, Juhan Li, Xuanzhou Chen, Louis D. Zhang, Shuguang Wang, Dianwen Song, Dongyong Sha   +9 more
wiley   +1 more source

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

Advanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang, Meng‐Hao Li, Liang Cheng, Tian‐Shou Zhang, Hui Hui, Yan Wang, Hong‐Pu Zhang, Bo‐Wen Liu, Lin Wang, Ying‐Wei Yang   +9 more
wiley   +1 more source

Anesthetic Management of a Pediatric Patient With Glucose-6-Phosphate Dehydrogenase Deficiency Undergoing Emergency Rigid Esophagoscopy: A Case Report. [PDF]

Cureus
Khaliq A, Grancaric N, Girshin M, Mendonca R, Suler BJ.   +4 more
europepmc   +1 more source

A new in vitro method for evaluating intravascular hemolysis

, 1997
The primary focus of this research is to develop an in vitro method that uses an appropriate formulation:blood ratio and contact time to evaluate the degree of hemolysis occurring after an intravenous injection.
Krzyzaniak, Joseph Frances, 1968-
core  

Amplification of Endoplasmic Reticulum Stress via Inhibiting Lipid Droplet Formation to Enhance Chemodynamic Immunotherapy

Advanced Science, EarlyView.
An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai, Shaoru Zhuang, Yang Zhu, Rujiang Ao, Meili Yu, Tingting Cui, Jun Wang, Xuegang Niu, Hongwei Huang, Shanshan Peng, Yu He, Lisen Lin, Huanghao Yang   +12 more
wiley   +1 more source

Stimulation of Eryptosis and Hemolysis by Adrenic Acid Involves Oxidative Stress, Calcium Elevation, and Metabolic Collapse. [PDF]

Int J Mol Sci
Alharthy FH, Alsughayyir J, Alfhili MA.
europepmc   +1 more source

Evidence for alcohol-mediated hemolysis and erythrophagocytosis

Alcohol-related liver disease (ALD) is the most common liver disease worldwide; however, its underlying molecular mechanisms remain poorly understood.
Antonio Riva, Zheng, Chaowen, Ane Zamalloa, Srinivasan, Parthi, Nigel Heaton, Stephan Immenschuh, Immenschuh, Stephan, Ines Silva, Hammad, Seddik, Steven Dooley, Siyuan Li, Parthi Srinivasan, Vanessa Rausch, Chen, Cheng, Guandou Yuan, Yuan, Guandou, Johannes Mueller, Cheng Chen, Adofina, Lissette, Seddik Hammad, He, Songqing, Krishna Menon, Shilpa Chokshi, Heaton, Nigel, Lyu, Huanran, Riva, Antonio, Li, Siyuan, Lissette Adofina, Silva, Ines, Zamalloa, Ane, Mueller, Sebastian, Huanran Lyu, Chokshi, Shilpa, Riva, Antonio; id_orcid, Chaowen Zheng, Rausch, Vanessa, Dooley, Steven, Menon, Krishna, Sebastian Mueller, Mueller, Johannes, Songqing He   +40 more
core   +1 more source