Results 1 to 10 of about 17,178,165 (354)
CellCell death supports morphogenesis during development and homeostasis after birth by removing damaged or obsolete cells. It also curtails the spread of pathogens by eliminating infected cells. Cell death can be induced by the genetically programmed suicide mechanisms of apoptosis, necroptosis, and pyroptosis, or it can be a consequence of dysregulated ...
Kim Newton +3 more
openaire +4 more sources
International Journal of Cell Biology, 2014 N ...
GIAMPIETRI, Claudia +2 more
openaire +6 more sources
Copper induces cell death by targeting lipoylated TCA cycle proteins
Science, 2022 Copper is an essential cofactor for all organisms, and yet it becomes toxic if concentrations exceed a threshold maintained by evolutionarily conserved homeostatic mechanisms. How excess copper induces cell death, however, is unknown.
P. Tsvetkov +17 more
semanticscholar +1 more source
Biology of Sex Differences, 2023 Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in Western countries, evolving into metabolic dysfunction-associated steatohepatitis (MASH) with a sexual dimorphism. Fertile women exhibit lower MASLD risk than men,
Carlos Cuño-Gómiz +7 more
doaj +1 more source
Prostate apoptosis response-4 and tumor suppression: it’s not just about apoptosis anymore
Cell Death and Disease, 2021 The tumor suppressor prostate apoptosis response-4 (Par-4) has recently turned ‘twenty-five’. Beyond its indisputable role as an apoptosis inducer, an increasing and sometimes bewildering, new roles for Par-4 are being reported.
Anees Rahman Cheratta +5 more
doaj +1 more source
Measurement and models accounting for cell death capture hidden variation in compound response. [PDF]
, 2020 Cancer cell sensitivity or resistance is almost universally quantified through a direct or surrogate measure of cell number. However, compound responses can occur through many distinct phenotypic outcomes, including changes in cell growth, apoptosis, and
Bae, Song Yi +5 more
core +1 more source
Necroptosis, pyroptosis and apoptosis: an intricate game of cell death
Cellular & Molecular Immunology, 2021 Cell death is a fundamental physiological process in all living organisms. Its roles extend from embryonic development, organ maintenance, and aging to the coordination of immune responses and autoimmunity.
D. Bertheloot, E. Latz, B. S. Franklin
semanticscholar +1 more source
Scientific Reports, 2021 In cancer cells only, TLR3 acquires death receptor properties by efficiently triggering the extrinsic pathway of apoptosis with Caspase-8 as apical protease.
Marie-Anaïs Locquet +6 more
doaj +1 more source
Cells, 2022 Immunogenic cell death (ICD) is a functionally unique form of cell death that promotes a T-cell-dependent anti-tumor immune response specific to antigens originating from dying cancer cells.
Dmitri V. Krysko +5 more
doaj +1 more source
Biology Direct, 2022 Background Rodents, such as mice, are vulnerable targets, and potential intermediate hosts, of SARS-CoV-2 variants of concern, including Alpha, Beta, Gamma, and Omicron.
Yichao Zhu +9 more
doaj +1 more source