Results 31 to 40 of about 9,068,395 (264)
SIRT1 inhibits mitochondrial hyperfusion associated mito-bulb formation to sensitize oral cancer cells for apoptosis in a mtROS-dependent signalling pathway
Cell Death and Disease, 2023 SIRT1 (NAD-dependent protein deacetylase sirtuin-1), a class III histone deacetylase acting as a tumor suppressor gene, is downregulated in oral cancer cells.Srimanta Patra, Amruta Singh, Prakash P. Praharaj, Nitish K. Mohanta, Mrutyunjay Jena, Birija S. Patro, Ali Abusharha, Shankargouda Patil, Sujit K. Bhutia +8 moredoaj +1 more sourceSpatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation
Nature Communications, 2020 Lysosomes are intracellular organelles containing degradative enzymes, and leakage of lysosomal contents into the cell is thought to trigger cell death.Saara Hämälistö, Jonathan Lucien Stahl, Elena Favaro, Qing Yang, Bin Liu, Line Christoffersen, Ben Loos, Claudia Guasch Boldú, Johanna A. Joyce, Thomas Reinheckel, Marin Barisic, Marja Jäättelä +11 moredoaj +1 more sourceUrsolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells
Cells, 2022 Cancer is one of the leading causes of death worldwide, thus the search for new cancer therapies is of utmost importance. Ursolic acid is a naturally occurring pentacyclic triterpene with a wide range of pharmacological activities including anti ...Ditte L. Fogde, Cristina P. R. Xavier, Kristina Balnytė, Lya K. K. Holland, Kamilla Stahl-Meyer, Christoffel Dinant, Elisabeth Corcelle-Termeau, Cristina Pereira-Wilson, Kenji Maeda, Marja Jäättelä +9 moredoaj +1 more sourceMolecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
, 2018 Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives.Gross, Atan, Vucic, Domagoj, Piacentini, Mauro, Altucci, Lucia, Adam, Dieter, Tsujimoto, Yoshihide, Wang, Ying, Elrod, John W, Pagano, Michele, Wells, James A, Garrido, Carmen, Thorburn, Andrew, De Maria, Ruggero, Lipton, Stuart A, Lockshin, Richard A, Rodrigues, Cecilia M P, Nagata, Shigekazu, Pasparakis, Manolis, Overholtzer, Michael, Blomgren, Klas, Boya, Patricia, Szabadkai, Gyorgy, Villunger, Andreas, Green, Douglas R, Andrews, David W, Gottlieb, Eyal, Lemasters, John J, Vitale, Ilio, Conrad, Marcus, Golstein, Pierre, Hardwick, J Marie, Sayan, Emre, Arama, Eli, Zakeri, Zahra, Muñoz-Pinedo, Cristina, Klionsky, Daniel J, Amelio, Ivano, Yuan, Junying, Bernassola, Francesca, Bianchi, Katiuscia, Silke, John, Fimia, Gian Maria, Dawson, Ted M, Kepp, Oliver, Strasser, Andreas, Knight, Richard A, Tang, Daolin, Vousden, Karen H, Karin, Michael, Nuñez, Gabriel, Harris, Isaac S, Zitvogel, Laurence, Lee, Sam W, Hengartner, Michael O, Linkermann, Andreas, Mehlen, Patrick, Wood, Will, MacFarlane, Marion, Penninger, Josef M, Panaretakis, Theocharis, García-Sáez, Ana J, Kumar, Sharad, Juin, Philippe P, Pereira, David M, Scorrano, Luca, DeBerardinis, Ralph J, Garg, Abhishek D, Kaiser, William J, Prehn, Jochen H M, Kroemer, Guido, Di Daniele, Nicola, Hetz, Claudio, Dynlacht, Brian D, Oberst, Andrew, Barlev, Nickolai A, Antonov, Alexey V, Fulda, Simone, Aaronson, Stuart A, Bazan, Nicolas G, Chipuk, Jerry E, De Laurenzi, Vincenzo, Vander Heiden, Matthew G, El-Deiry, Wafik S, Virgin, Herbert W, Cubillos-Ruiz, Juan R, Malewicz, Michal, Rudel, Thomas, Melino, Gerry, Czabotar, Peter E, Luedde, Tom, Marine, Jean-Christophe, Blagosklonny, Mikhail V, Chan, Francis K-M, Tait, Stephen W G, Jost, Philipp J, Levine, Beth, Kaufmann, Thomas, Alnemri, Emad S, Dawson, Valina L, Pinton, Paolo, Kitsis, Richard N, Ryan, Kevin M, Sistigu, Antonella, Hajnoczky, Gyorgy, Baehrecke, Eric H, Cheng, Emily H, Dixon, Scott J, Carmona-Gutierrez, Didac, Ichijo, Hidenori, López-Otín, Carlos, Rizzuto, Rosario, Kimchi, Adi, Joseph, Bertrand, Medema, Jan Paul, Duckett, Colin S, Tavernarakis, Nektarios, Cecconi, Francesco, Pervaiz, Shazib, Greene, Lloyd A, Stockwell, Brent R, Miao, Edward A, Moll, Ute M, Abrams, John M, Vanden Berghe, Tom, Wagner, Erwin F, Lowe, Scott W, Ciechanover, Aaron, Melino, Sonia, Vandenabeele, Peter, Agostinis, Patrizia, Molkentin, Jeffery D, Brenner, Catherine, Martin, Seamus J, Peter, Marcus E, Cohen, Gerald M, Gronemeyer, Hinrich, Madeo, Frank, Gavathiotis, Evripidis, Dixit, Vishva M, Galluzzi, Lorenzo, Puthalakath, Hamsa, Jäättelä, Marja, Rehm, Markus, Campanella, Michelangelo, Shao, Feng, Wallach, David, Meier, Pascal, Borner, Christoph, Candi, Eleonora, Walczak, Henning, Cidlowski, John A, Chandel, Navdeep S, Deshmukh, Mohanish, Martinou, Jean-Claude, Rabinovich, Gabriel A, Lugli, Enrico, Malorni, Walter, Di Virgilio, Francesco, Rubinsztein, David C, Zhivotovsky, Boris, Oren, Moshe, Annicchiarico-Petruzzelli, Margherita, Shi, Yufang, Simon, Hans-Uwe, Turk, Boris, Manic, Gwenola, Bertrand, Mathieu J M, Debatin, Klaus-Michael, D'Angiolella, Vincenzo +168 morecore +2 more sourcesSolid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
Pediatric Blood &Cancer, EarlyView.ABSTRACT
Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach +18 morewiley +1 more sourceEvolution of apoptosis-like programmed cell death in unicellular protozoan parasites [PDF]
, 2011 Apoptosis-like programmed cell death (PCD) has recently been described in multiple taxa of unicellular protists, including the protozoan parasites Plasmodium, Trypanosoma and Leishmania.Sarah E Reece, Szymon Kaczanowski, Reece, Sarah E., Kaczanowski Szymon, Kaczanowski, S., Reece, S.E., Reece Sarah E, Mohammed Sajid, Sajid Mohammed, Sajid, M., Reece, Sarah, Sajid, Mohammed, Kaczanowski, Szymon +12 morecore +1 more sourceEvidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup +15 morewiley +1 more source
