Results 31 to 40 of about 2,113,177 (314)
Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites [PDF]
, 2011 Apoptosis-like programmed cell death (PCD) has recently been described in multiple taxa of unicellular protists, including the protozoan parasites Plasmodium, Trypanosoma and Leishmania.
Sarah E Reece +12 more
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Neuron, 1998 We thank J.-F. Brunet, P. G. H. Clarke, O. deLapeyriere, P. Golstein, J.-C. Martinou, C. Mulle, and R. W. Oppenheim for thoughtful comments on the manuscript and C. Waldmann for artwork. In a short review such as this, it is not possible to establish precedence for all ideas or mechanisms, many of which originate from (or are still confined to) studies
Pettmann, Brigitte +1 more
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Programmed cell death in type II neuroblast lineages is required for central complex development in the Drosophila brain [PDF]
, 2012 Background: The number of neurons generated by neural stem cells is dependent upon the regulation of cell proliferation and by programmed cell death.
Heinrich Reichert +5 more
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Cell Death and Disease, 2023 SIRT1 (NAD-dependent protein deacetylase sirtuin-1), a class III histone deacetylase acting as a tumor suppressor gene, is downregulated in oral cancer cells.
Srimanta Patra +8 more
doaj +1 more source
Cells, 2022 Cancer is one of the leading causes of death worldwide, thus the search for new cancer therapies is of utmost importance. Ursolic acid is a naturally occurring pentacyclic triterpene with a wide range of pharmacological activities including anti ...
Ditte L. Fogde +9 more
doaj +1 more source
Journal of Nuclear Medicine, 2014 There is currently a need for imaging methods capable of detecting cell death in tissues and the early onset of tumor cell death resulting from therapy. However, to date, no probe has been approved for routine imaging of cell death in the clinic. The challenge is to identify hallmarks of cell death, which have clinical relevance, and then to develop ...
André A, Neves, Kevin M, Brindle
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The mutualistic fungus Piriformospora indica colonizes Arabidopsis roots by inducing an endoplasmic reticulum stress-triggered caspase-dependent cell death [PDF]
, 2012 In Arabidopsis thaliana roots, the mutualistic fungus Piriformospora indica initially colonizes living cells, which die as the colonization proceeds. We aimed to clarify the molecular basis of this colonization-associated cell death.
Zechmann, B. +4 more
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Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation
Nature Communications, 2020 Lysosomes are intracellular organelles containing degradative enzymes, and leakage of lysosomal contents into the cell is thought to trigger cell death.
Saara Hämälistö +11 more
doaj +1 more source
Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1. [PDF]
, 2012 Melanoma is an often fatal form of skin cancer which is remarkably resistant against radio- and chemotherapy. Even new strategies that target RAS/RAF signaling and display unprecedented efficacy are characterized by resistance mechanisms.
Berking, Carola +18 more
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The International Journal of Developmental Biology, 2015 Currently, it is widely acknowledged that a proactive anticancer immunosurveillance mechanism takes part in the rejection of neoplastic lesions before they progress towards a benign or malignant tumour. However in cases of very aggressive neoplastic lesions consisting of cells with high mutational diversity, cancer cell variants might be formed that ...
Garg, Abhishek +3 more
openaire +4 more sources