Results 11 to 20 of about 9,068,395 (264)

PTEN-lipid Binding Assay

open access: yesBio-Protocol, 2013
The lipid and protein interactions are an integral and important part of many cellular signaling pathways. The understanding of the selective and specific interaction of the given lipid molecule with the target protein is required for studying cellular ...
Sridhar Kavela   +2 more
doaj   +1 more source

Cellular stress responses: cell survival and cell death [PDF]

open access: yes, 2010
Cells can respond to stress in various ways ranging from the activation of survival pathways to the initiation of cell death that eventually eliminates damaged cells.
Afshin Samali   +12 more
core   +1 more source

Inhibition of apoptosis prevents West Nile virus induced cell death. [PDF]

open access: yes, 2007
We found that WNV infection induces cell death in the brain-derived tumour cell line T98G by apoptosis under involvement of constituents of the extrinsic as well as the intrinsic apoptotic pathways.
Michaelis, Martin   +10 more
core   +1 more source

Entosis: The emerging face of non-cell-autonomous type IV programmed death

open access: yesBiomedical Journal, 2017
The present review summarizes recent experimental evidences about the existence of the non-cell-autonomous death entosis in physiological and pathophysiological contexts, discusses some aspects of this form of cell death, including morphological ...
Isabelle Martins   +10 more
doaj   +1 more source

Cell arrest and cell death in mammalian preimplantation development [PDF]

open access: yes, 2011
The causes, modes, biological role and prospective significance of cell death in preimplantation development in humans and other mammals are still poorly understood.
Tuna Güngör   +24 more
core   +2 more sources

Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics

open access: yesOncoImmunology, 2017
The expression “immunogenic cell death” (ICD) refers to a functionally unique form of cell death that facilitates (instead of suppressing) a T cell-dependent immune response specific for dead cell-derived antigens. ICD critically relies on the activation
Abhishek D. Garg   +8 more
doaj   +1 more source

Cell-in-cell structure mediates in-cell killing suppressed by CD44

open access: yesCell Discovery, 2022
Penetration of immune cells into tumor cells was believed to be immune-suppressive via cell-in-cell (CIC) mediated death of the internalized immune cells.
Yan Su   +17 more
doaj   +1 more source

The safety of sotagliflozin in the therapy of diabetes mellitus type 1 and type 2: A meta-analysis of randomized trials

open access: yesFrontiers in Endocrinology, 2022
BackgroundDiabetes mellitus (DM) is a global health problem, and it has become a shocking threat in the contemporary era. The objective of this study was to analyze the safety of sotagliflozin in patients with DM systematically and intuitively.MethodsOn ...
Feifei Zhou   +7 more
doaj   +1 more source

Macrophage biology plays a central role during ionizing radiation-elicited tumor response

open access: yesBiomedical Journal, 2017
Radiation therapy is one of the major therapeutic modalities for most solid tumors. The anti-tumor effect of radiation therapy consists of the direct tumor cell killing, as well as the modulation of tumor microenvironment and the activation of immune ...
Qiuji Wu   +5 more
doaj   +1 more source

Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis

open access: yesCell Death and Disease, 2021
Ferroptosis is a type of regulated cell death characterized by ROS accumulation and devastating lipid peroxidation (LPO). The role of acid sphingomyelinase (ASM), a key enzyme in sphingolipid metabolism, in the induction of apoptosis has been studied ...
Faisal Thayyullathil   +6 more
doaj   +1 more source

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