Results 21 to 30 of about 17,178,165 (354)

Alternative cell death pathways and cell metabolism [PDF]

, 2013
While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells.
Fulda, Simone
core   +2 more sources

GPX4 in cell death, autophagy, and disease

Autophagy, 2023
Selenoprotein GPX4 (glutathione peroxidase 4), originally known as PHGPX (phospholipid hydroperoxide glutathione peroxidase), is the main oxidoreductase in the use of glutathione as a reducing agent in scavenging lipid peroxidation products.
Yangchun Xie, Rui Kang, D. Klionsky, D. Tang   +3 more
semanticscholar   +1 more source

PTEN-lipid Binding Assay

Bio-Protocol, 2013
The lipid and protein interactions are an integral and important part of many cellular signaling pathways. The understanding of the selective and specific interaction of the given lipid molecule with the target protein is required for studying cellular ...
Sridhar Kavela, Swapnil Shinde, Subbareddy Maddika   +2 more
doaj   +1 more source

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Cell Death and Differentiation, 2018
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives.
L. Galluzzi, I. Vitale, S. Aaronson, J. Abrams, D. Adam, P. Agostinis, E. Alnemri, L. Altucci, I. Amelio, D. Andrews, M. Annicchiarico-Petruzzelli, A. Antonov, E. Arama, E. Baehrecke, N. Barlev, N. Bazan, F. Bernassola, M. Bertrand, K. Bianchi, M. V. Blagosklonny, K. Blomgren, C. Borner, P. Boya, C. Brenner, M. Campanella, E. Candi, D. Carmona‐Gutierrez, F. Cecconi, F. K. Chan, N. Chandel, E. Cheng, J. Chipuk, J. Cidlowski, A. Ciechanover, G. Cohen, M. Conrad, J. Cubillos-Ruiz, P. Czabotar, V. D’Angiolella, T. Dawson, V. Dawson, V. de Laurenzi, R. De Maria, K. Debatin, R. Deberardinis, M. Deshmukh, N. Di Daniele, F. Di Virgilio, V. Dixit, S. Dixon, C. Duckett, B. Dynlacht, W. El-Deiry, J. Elrod, G. Fimia, S. Fulda, A. García-Sáez, Abhishek D Garg, C. Garrido, E. Gavathiotis, P. Golstein, E. Gottlieb, D. Green, L. Greene, H. Gronemeyer, A. Gross, G. Hajnóczky, J. Hardwick, I. Harris, M. Hengartner, C. Hetz, H. Ichijo, M. Jäättelä, B. Joseph, P. Jost, P. Juin, W. Kaiser, M. Karin, T. Kaufmann, O. Kepp, A. Kimchi, R. Kitsis, D. Klionsky, R. Knight, Sharad Kumar, Sam W. Lee, J. Lemasters, B. Levine, A. Linkermann, S. Lipton, R. Lockshin, C. López-Otín, S. Lowe, Tom Luedde, E. Lugli, M. MacFarlane, F. Madeo, M. Malewicz, W. Malorni, G. Manic, J. Marine, Seamus J. Martin, J. Martinou, J. Medema, P. Mehlen, P. Meier, S. Melino, Edward A. Miao, J. Molkentin, U. Moll, C. Muñoz-Pinedo, S. Nagata, G. Núñez, A. Oberst, M. Oren, M. Overholtzer, M. Pagano, T. Panaretakis, M. Pasparakis, J. Penninger, David M. Pereira, S. Pervaiz, M. Peter, M. Piacentini, P. Pinton, J. Prehn, H. Puthalakath, G. Rabinovich, M. Rehm, R. Rizzuto, C. Rodrigues, D. Rubinsztein, T. Rudel, K. Ryan, E. Sayan, L. Scorrano, F. Shao, Yufang Shi, J. Silke, H. Simon, A. Sistigu, B. Stockwell, A. Strasser, G. Szabadkai, S. Tait, D. Tang, Nektarios Tavernarakis, A. Thorburn, Y. Tsujimoto, B. Turk, T. Vanden Berghe, P. Vandenabeele, M. V. Vander Heiden, A. Villunger, H. Virgin, K. Vousden, D. Vučić, E. Wagner, H. Walczak, D. Wallach, Ying Wang, J. Wells, Will Wood, Junying Yuan, Z. Zakeri, B. Zhivotovsky, L. Zitvogel, G. Melino, G. Kroemer   +168 more
semanticscholar   +1 more source

Cuproptosis: p53-regulated metabolic cell death?

Cell Death and Differentiation, 2023
Cuproptosis is a novel type of copper-induced cell death that primarily occurs in cells that utilize oxidative phosphorylation as the main metabolic pathway to produce energy.
Chen Xiong, H. Ling, Qian Hao, Xiang Zhou   +3 more
semanticscholar   +1 more source

Cell-in-cell structure mediates in-cell killing suppressed by CD44

Cell Discovery, 2022
Penetration of immune cells into tumor cells was believed to be immune-suppressive via cell-in-cell (CIC) mediated death of the internalized immune cells.
Yan Su, Hongyan Huang, Tianzhi Luo, You Zheng, Jie Fan, He Ren, Meng Tang, Zubiao Niu, Chenxi Wang, Yuqi Wang, Zhengrong Zhang, Jianqing Liang, Banzhan Ruan, Lihua Gao, Zhaolie Chen, Gerry Melino, Xiaoning Wang, Qiang Sun   +17 more
doaj   +1 more source

The convergence of radiation and immunogenic cell death signaling pathways. [PDF]

, 2012
Ionizing radiation (IR) triggers programmed cell death in tumor cells through a variety of highly regulated processes. Radiation-induced tumor cell death has been studied extensively in vitro and is widely attributed to multiple distinct mechanisms ...
Barcellos-Hoff, Mary H, Demaria, Sandra, Formenti, Silvia C, Golden, Encouse B, Pellicciotta, Ilenia   +4 more
core   +2 more sources

Entosis: The emerging face of non-cell-autonomous type IV programmed death

Biomedical Journal, 2017
The present review summarizes recent experimental evidences about the existence of the non-cell-autonomous death entosis in physiological and pathophysiological contexts, discusses some aspects of this form of cell death, including morphological ...
Isabelle Martins, Syed Qasim Raza, Laurent Voisin, Haithem Dakhli, Frédéric Law, Dorine De Jong, Awatef Allouch, Maxime Thoreau, Catherine Brenner, Eric Deutsch, Jean-Luc Perfettini   +10 more
doaj   +1 more source

The safety of sotagliflozin in the therapy of diabetes mellitus type 1 and type 2: A meta-analysis of randomized trials

Frontiers in Endocrinology, 2022
BackgroundDiabetes mellitus (DM) is a global health problem, and it has become a shocking threat in the contemporary era. The objective of this study was to analyze the safety of sotagliflozin in patients with DM systematically and intuitively.MethodsOn ...
Feifei Zhou, Feifei Zhou, Nannan Du, Nannan Du, Lulin Zhou, Chenxi Wang, He Ren, Qiang Sun   +7 more
doaj   +1 more source

Programmed cell death [PDF]

WormBook, 2005
Programmed cell death is an integral component of C. elegans development. Genetic studies in C. elegans have led to the identification of more than two dozen genes that are important for the specification of which cells should live or die, the activation of the suicide program, and the dismantling and removal of dying cells.
Barbara, Conradt, Ding, Xue
openaire   +2 more sources