Results 321 to 330 of about 200,118 (403)

Non‐Amphiphilic Antimicrobial Polymers

open access: yesAngewandte Chemie International Edition, Accepted Article.
Antimicrobial resistance (AMR) is a severe threat to modern health care and must be addressed to prevent millions of deaths in the coming decades. Antimicrobial polymers (APs) do not provoke resistances and are promising alternatives to conventional antibiotics. Classic APs possess an amphiphilic structure (cationic and hydrophobic). Herein we question
Alain M. Bapolisi   +15 more
wiley   +1 more source

Preparation, Characterization, and Antimicrobial Activities of Ceragenins Incorporated Into Polyvinyl Alcohol/Gelatin/Sodium Alginate‐Based Hydrogels for Treatment of Burn Wounds

open access: yesJournal of Applied Polymer Science, EarlyView.
ABSTRACT Ceragenins are synthetic molecules that mimic antimicrobial peptides (AMPs) in the human immune system. They feature a bile acid‐based structure with appended positively charged groups that disrupt bacterial cell membranes, leading to microbial cell death or inactivation.
Nawal Aljayyousi   +6 more
wiley   +1 more source

Antifibrotic effects of specific targeting of the 5‐hydroxytryptamine 2B receptor (5‐HT2BR) in murine models and ex vivo models of scleroderma skin

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh   +12 more
wiley   +1 more source

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