Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan+3 more
wiley +1 more source
Hepatic Abscess With Clostridium perfringens Bacteremia Leading to Hemolysis: A Case Report. [PDF]
Collins Ii J+4 more
europepmc +1 more source
Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza+26 more
wiley +1 more source
Association between hematological disorders and gallbladder stones: A review of current evidence. [PDF]
Qu ZJ, Wang YN, Liu YH, Duan RH.
europepmc +1 more source
Cefuroxime axetil dosing regimens and probability of target attainment in adults and children
Aims Cefuroxime axetil exists in several dosage forms for oral administration, and is indicated for treatment of respiratory, genitourinary, skin and soft tissue infections. Evolving patterns of bacterial susceptibility, expressed as increasing minimum inhibitory concentrations (MICs), warrant monitoring of antibiotic efficacy.
Sven C. van Dijkman+3 more
wiley +1 more source
<i>In vitro</i> feasibility of bovine and canine whole blood and commercially prepared canine packed red blood cells as a source of xenotransfusion in swine (<i>Sus scrofa domestica</i>). [PDF]
Diaz V+6 more
europepmc +1 more source
Paediatric rare diseases: Can large language models assist off‐label prescribing?
Aims To evaluate the effectiveness and reliability of large language models (LLMs) in retrieving and synthesizing biomedical information to support off‐label drug prescribing in paediatric rare diseases, and to compare their performance with human‐authored references in terms of scientific rationale, adverse events and drug interactions.
Anna Flamigni+3 more
wiley +1 more source
Editorial: Current treatment strategies and integrative medicine for management of pain in sickle cell disease. [PDF]
Richardson KA+3 more
europepmc +1 more source
Correction: Multi-enzymatic biomimetic cerium-based MOFs mediated precision chemodynamic synergistic antibacteria and tissue repair for MRSA-infected wounds. [PDF]
Chen S+10 more
europepmc +1 more source
Exposure to sub-zero temperatures down to -11 °C does not impact packed red cells storage quality. [PDF]
Derkenne C+16 more
europepmc +1 more source