Results 31 to 40 of about 92,935 (295)

Nocturnal Hypoxemia Rather Than Obstructive Sleep Apnea Is Associated With Decreased Red Blood Cell Deformability and Enhanced Hemolysis in Patients With Sickle Cell Disease

Frontiers in Physiology, 2021
Background: Although obstructive sleep apnea (OSA) could act as a modulator of clinical severity in sickle cell disease (SCD), few studies focused on the associations between the two diseases.Research Question: The aims of this study were: (1) to explore
Emeric Stauffer, Emeric Stauffer, Emeric Stauffer, Emeric Stauffer, Solène Poutrel, Solène Poutrel, Giovanna Cannas, Alexandra Gauthier, Alexandra Gauthier, Alexandra Gauthier, Romain Fort, Romain Fort, Romain Fort, Romain Fort, Yves Bertrand, Céline Renoux, Céline Renoux, Céline Renoux, Philippe Joly, Philippe Joly, Philippe Joly, Camille Boisson, Camille Boisson, Arnaud Hot, Laure Peter-Derex, Laure Peter-Derex, Vincent Pialoux, Thierry PetitJean, Thierry PetitJean, Philippe Connes, Philippe Connes   +30 more
doaj   +1 more source

Joule‐Assisted Nanotherapeutic Urethral Stent (JANUS) for Spatiotemporal Theragenerative Treatment of Urethral Strictures

Advanced Functional Materials, EarlyView.
Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na, Yubeen Park, Hyun Lee, Song Hee Kim, Seojoon Bang, Hyeong Seok Kang, Chan Ho Moon, Ju Yeong Gwon, Jong Hwa Seo, Min‐Ho Kang, Soo‐Hong Lee, Gi Doo Cha, Wooram Park, Heemin Kang, Jung‐Hoon Park, Hyun‐Do Jung   +15 more
wiley   +1 more source

The Emerging 4D Printing of Shape‐Memory Thermomorphs for Self‐Adaptative Biomedical Implants

Advanced Functional Materials, EarlyView.
4D printing enables the creation of smart implants that adapt to changing conditions in the human body over time. At the core of this technology are shape‐memory thermomorphs (SMTMs). This review offers an in‐depth analysis of 4D printing with SMTMs, emphasizing the latest advancements in smart materials, stimuli, programming principles, and their ...
Aixiang Ding, Fang Tang, Eben Alsberg
wiley   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Eco‐Fabricated Nanowave‐Textured Implants Drive Microtubule‐Assisted Nuclear Mechanotransduction and Chromatin Modification: Biophysical Priming for Osteogenesis and Bone Regeneration

Advanced Functional Materials, EarlyView.
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong, Ji‐Young Yoon, Junyong Ahn, Byunghak Lee, Sung‐Min Park, Jae‐Heon Kim, Buuvee Bayarkhangai, Yu Jin Kim, Sak Lee, Jonathan C. Knowles, Moon‐Young Kim, DongJun Lee, Sang‐Hoon Rhee, Hae‐Hyoung Lee, Hae‐Won Kim, Jung‐Hwan Lee   +15 more
wiley   +1 more source

Hemolysis and its outcome following percutaneous closure of cardiac defects among children and adolescents: a prospective study

Italian Journal of Pediatrics, 2019
Background Transcatheter closure of intracardiac defects might be complicated by intravascular hemolysis. We evaluated hemolysis and its outcome after transcatheter closure of these defects.
Hamid Amoozgar, Romeileh Soltani, Mohammadreza Edraki, Nima Mehdizadegan, Hamid Mohammadi, Gholamhossein Ajami, Mohammad Borzouee, Amir Naghshzan, Kambiz Keshavarz   +8 more
doaj   +1 more source

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

PENGARUH HEMOLISIS TERHADAP KADAR SERUM GLUTAMATE PYRUVATE TRANSAMINASE (SGPT) SEBAGAI SALAH SATU PARAMETER FUNGSI HATI

Journal of Muhammadiyah Medical Laboratory Technologist, 2017
PENGARUH HEMOLISIS TERHADAP KADAR SERUM GLUTAMATE PYRUVATE TRANSAMINASE (SGPT) SEBAGAI SALAH SATU PARAMETER FUNGSI HATI   Hartono Kahar1 1) Prodi Ilmu Patologi Klinik, Fakultas Kedokteran, Universitas Airlangga hartonokahar123@gmail.com Abstract SGPT ...
hartono kahar
doaj  

Pediatric hemolysis in emergency departments: Prevalence, risk factors, and clinical implications.

PLoS ONE
ObjectiveThis study aimed to analyze the prevalence, risk factors, and clinical implications of hemolyzed laboratory samples in the pediatric emergency department (ED), a subject on which existing data remains scarce.MethodsWe conducted a multi-site ...
Nicholas Mielke, Ray Lee, Amit Bahl
doaj   +1 more source

Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury

Frontiers in Pharmacology, 2019
Massive intravascular hemolysis is associated with acute kidney injury (AKI). Nuclear factor erythroid-2-related factor 2 (Nrf2) plays a central role in the defense against oxidative stress by activating the expression of antioxidant proteins.
Alfonso Rubio-Navarro, Cristina Vázquez-Carballo, Melania Guerrero-Hue, Cristina García-Caballero, Carmen Herencia, Eduardo Gutiérrez, Claudia Yuste, Ángel Sevillano, Manuel Praga, Javier Egea, Javier Egea, Javier Egea, Pablo Cannata, Isabel Cortegano, Belén de Andrés, María Luisa Gaspar, Susana Cadenas, Patrycja Michalska, Patrycja Michalska, Rafael León, Rafael León, Alberto Ortiz, Jesús Egido, Juan Antonio Moreno, Juan Antonio Moreno   +24 more
doaj   +1 more source