Results 31 to 40 of about 89,871 (313)

Hemolysis after Oral Artemisinin Combination Therapy for Uncomplicated Plasmodium falciparum Malaria

Emerging Infectious Diseases, 2016
Episodes of delayed hemolysis 2–6 weeks after treatment of severe malaria with intravenous artesunate have been described. We performed a prospective observational study of patients with uncomplicated malaria to investigate whether posttreatment ...
Florian Kurth, Tilman Lingscheid, Florian Steiner, Miriam S. Stegemann, Sabine Bélard, Nikolai Menner, Peter Pongratz, Johanna Kim, Horst von Bernuth, Beate Mayer, Georg Damm, Daniel Seehofer, Abdulgabar Salama, Norbert Suttorp, Thomas Zoller   +14 more
doaj   +1 more source

Microstreaming by ultrasound contrast microbubble between two parallel walls: shear stress and streamlines [PDF]

arXiv, 2022
Acoustic microstreaming has several industrial, therapeutic, and biomedical applications - Acoustic cleaning, micromixing, microfluid transport, hemolysis, sonoporation. The acoustic microstreaming due to the oscillation of ultrasound contrast microbubbles in the middle of the gap between two parallel walls is studied numerically. Axisymmetric Boundary
arxiv  

Factors in Hemolysis [PDF]

Journal of Infectious Diseases, 1908
During an investigation in hemolysis, extending over about three years, a number of unsuspected phenomena have been encountered. The discovery of these phenomena has modified the original comparatively simple concept of hemolytic serum, so that in place of the two components at first regarded as the only active substances in such serum, at least a ...
openaire   +2 more sources

Interesting case of G6PD deficiency anemia with severe hemolysis

Asian Journal of Transfusion Science, 2013
Severe hemolysis was observed in a critically ill patient with G6Pd deficiency where the causative trigger could not be identified. We describe one young patient with severe hemolysis treated with two cycles of plasmapheresis which proved to be an ...
Anupam Chhabra, David Raj, Pankaj N Choudhary, Ashok Grover   +3 more
doaj   +1 more source

Nocturnal Hypoxemia Rather Than Obstructive Sleep Apnea Is Associated With Decreased Red Blood Cell Deformability and Enhanced Hemolysis in Patients With Sickle Cell Disease

Frontiers in Physiology, 2021
Background: Although obstructive sleep apnea (OSA) could act as a modulator of clinical severity in sickle cell disease (SCD), few studies focused on the associations between the two diseases.Research Question: The aims of this study were: (1) to explore
Emeric Stauffer, Emeric Stauffer, Emeric Stauffer, Emeric Stauffer, Solène Poutrel, Solène Poutrel, Giovanna Cannas, Alexandra Gauthier, Alexandra Gauthier, Alexandra Gauthier, Romain Fort, Romain Fort, Romain Fort, Romain Fort, Yves Bertrand, Céline Renoux, Céline Renoux, Céline Renoux, Philippe Joly, Philippe Joly, Philippe Joly, Camille Boisson, Camille Boisson, Arnaud Hot, Laure Peter-Derex, Laure Peter-Derex, Vincent Pialoux, Thierry PetitJean, Thierry PetitJean, Philippe Connes, Philippe Connes   +30 more
doaj   +1 more source

Analysis of the suitability of an effective viscosity to represent interactions between red blood cells [PDF]

arXiv, 2023
Many methods to computationally predict red blood cell damage have been introduced, and among these are Lagrangian methods which track the cells along their pathlines. Such methods typically do not explicitly include cell-cell interactions. Due to the high volume fraction of red blood cells in blood, these interactions could impact cell mechanics and ...
arxiv  

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source

Purinergic Receptor Antagonists Inhibit Hemolysis Induced by Clostridium perfringens Alpha Toxin

Pathogens
Clostridium perfringens alpha toxin (CPA), which causes yellow lamb disease in sheep and gas gangrene and food poisoning in humans, is produced by all types of C. perfringens and is the major virulence determinant of C. perfringens type A.
Zishuo Guo, Nan Yue, Ming Chen, Jiaxin Li, Ruomei Lv, Jing Wang, Tingting Liu, Jing Huang, Shan Gao, Yanwei Li, Bing Yuan, Jinglin Wang, Lin Kang, Bin Ji, Wenwen Xin   +14 more
doaj   +1 more source

HEMOLYSIS AND AGGLUTINATION IN TRANSPLANTATION [PDF]

Journal of the American Medical Association, 1915
In studies of the conditions incident to the cause of autolysis and the dissolution of the transplant, we devoted especial attention to the influence of hemolysis and agglutination on transplants. No question is more timely than that concerning the causes of their absorption. Most authors lay great stress on the importance of eliminating the two great
openaire   +3 more sources

Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding

FEBS Open Bio, EarlyView.
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla, Faiza Abbas, Luigia Rossi, Mauro Magnani, Sara Biagiotti   +4 more
wiley   +1 more source