Results 41 to 50 of about 200,118 (403)
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Complement system activation occurs in sickle cell disease and other hemolytic disorders, but the pathological relevance and the acquisition of a complement-activating phenotype by host cells during hemolysis remain unclear.
N. Merle +9 more
semanticscholar +1 more source
Analysis on Evaluation Method of Mechanically-Induced Hemolysis of Medical Devices
Zhongguo yiliao qixie zazhiMechanically-induced hemolysis is an important index for evaluating the blood compatibility of medical devices. It mainly evaluates the risk of mechanical hemolysis under simulated clinical use conditions of medical devices.
Jianxiu ZHU, Zhichen ZHAI
doaj +1 more source
Preparation and Biomedical properties of transparent chitosan/gelatin/honey/aloe vera nanocomposite [PDF]
Nanomedicine Research Journal, 2020 Objective(s): Biodegradable polymers are featured with notable potentials for biotechnology and bioengineering purposes. Still, there are limitations in their applicability so that in many cases composite forms are used.
samira samadieh, minoo sadri
doaj +1 more source
Investigating the effect of turbulence on hemolysis through cell-resolved fluid-structure interaction simulations [PDF]
arXiv, 2023 Existing hemolysis algorithms are often constructed for laminar flows that expose red blood cells to a constant rate of shear. It remains an open question whether such models are applicable to turbulent flows, where there is a significant variation in shear rate along cell trajectories. To evaluate the effect of turbulence on hemolysis, we perform cell-
arxiv
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles.
JCI Insight, 2018 In hemolytic diseases, such as sickle cell disease (SCD), intravascular hemolysis results in the release of hemoglobin, heme, and heme-loaded membrane microvesicles in the bloodstream.
N. Merle +25 more
semanticscholar +1 more source
Invisible hemolysis in serum samples interferes in NSE measurement
Tumori, 2020 Introduction: The accuracy of serum neuron-specific enolase (NSE) measurements is critical, particularly in neurologic diseases and cancer. NSE measurements are compromised by slight, even invisible, hemolysis, which can produce apparently higher NSE ...
A. Mastroianni, R. Panella, D. Morelli
semanticscholar +1 more source
Shape Optimization of hemolysis for shear thinning flows in moving domains [PDF]
arXiv, 2023 We consider the $3$D problem of shape optimization of blood flows in moving domains. Such a geometry is adopted to take into account the modeling of rotating systems and blood pumps for instance. The blood flow is described by generalized Navier-Stokes equations, in the particular case of shear-thinning flows.
arxiv
Journal of the American Medical Association (JAMA), 2005 CONTEXT The efficient sequestration of hemoglobin by the red blood cell membrane and the presence of multiple hemoglobin clearance mechanisms suggest a critical need to prevent the buildup of this molecule in the plasma.
R. Rother +3 more
semanticscholar +1 more source
BMC Genomics, 2022 Background Genetic variants have been found to influence red blood cell (RBC) susceptibility to hemolytic stress and affect transfusion outcomes and the severity of blood diseases.
Fang Fang +8 more
doaj +1 more source
PeptideBERT: A Language Model based on Transformers for Peptide Property Prediction [PDF]
arXiv, 2023 Recent advances in Language Models have enabled the protein modeling community with a powerful tool since protein sequences can be represented as text. Specifically, by taking advantage of Transformers, sequence-to-property prediction will be amenable without the need for explicit structural data.
arxiv