Results 51 to 60 of about 89,871 (313)
Pediatric hemolysis in emergency departments: Prevalence, risk factors, and clinical implications.
PLoS ONEObjectiveThis study aimed to analyze the prevalence, risk factors, and clinical implications of hemolyzed laboratory samples in the pediatric emergency department (ED), a subject on which existing data remains scarce.MethodsWe conducted a multi-site ...
Nicholas Mielke, Ray Lee, Amit Bahl
doaj +1 more source
Journal of Pharmacopuncture, 2022 Objectives: Sweet bee venom (sBV) is purified from Apis mellifera, containing a high level of melittin—its main component. It has been used as a therapeutic agent for pain relief and anti-inflammation, as well as for treating neuronal abnormalities ...
Yu-Na Hwang +4 more
doaj +1 more source
Automated CFD shape optimization of stator blades for the PediaFlow pediatric ventricular assist device [PDF]
arXiv, 2022 PediaFlow is a miniature mixed-flow ventricular assist device for neonates and toddlers. PediaFlow has a fully magnetically levitated rotor which improves biocompatibility, but the increased length of the rotor creates a long annular passage where fluid energy is lost.
arxiv
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Hemolysis and its impact on cell-free microRNA biomarkers
Frontiers in Genetics, 2013 Cell-free microRNAs in plasma and serum have become a promising source of biomarkers for various diseases. Despite rapid progress in this field, there remains a lack of consensus regarding optimal quantification methods, reference genes and quality ...
Michaela B Kirschner +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.High glucose‐ and acid‐responsive hydrogel with dynamic covalent bond solubilized with flavonoids (Gel‐Flavonoids) is designed for diabetic wound healing. The Gel‐Flavonoids adapt to irregular wound shapes and release antioxidants in high‐glucose environments, effectively reducing reactive oxygen species.
Qiang Zeng +9 more
wiley +1 more source
Advanced Materials, EarlyView.A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen +7 more
wiley +1 more source
Oxidative hemolysis of erythrocytes [PDF]
Biochemistry and Molecular Biology Education, 2006 AbstractThis exercise for students will allow them to simultaneously observe lipid peroxidation and consequent hemolysis of rat erythrocytes and the effect of sodium azide, a catalase inhibitor, on these processes. It will also demonstrate a protective action of antioxidants, the therapeutically used N‐acetylcysteine and albumins present in plasma.
Lidia Włodek, Dorota Kusior
openaire +3 more sources
Advanced Materials, EarlyView.Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu +9 more
wiley +1 more source
MicromachinesMicrofluidic devices promise to overcome the limitations of conventional hemodialysis and oxygenation technologies by incorporating novel membranes with ultra-high permeability into portable devices with low blood volume.
Nayeem Imtiaz +4 more
doaj +1 more source