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Liver Involvement in Children with Hemolytic Uremic Syndrome: Clinical Significance and Prognostic Value [PDF]

Children
Background/Objectives: Hemolytic uremic syndrome is a thrombotic microangiopathy characterized by hemolytic anemia, thrombocytopenia, and acute kidney injury.
Ezgi Kıran Taşcı, Bora Kunay, Eylem Tazegül Çokgezer, Ezgi Yavuz, Doğan Barut, Pınar Yazıcı Özkaya, Kübra Cebeci, Sevgin Taner, İpek Kaplan Bulut, Miray Karakoyun   +9 more
doaj   +2 more sources

Atypical hemolytic uremic syndrome : update on the complement system and what is new [PDF]

, 2010
Atypical hemolytic uremic syndrome (aHUS) is a rare disease of microangiopathic hemolytic anemia, thrombocytopenia, and predominant renal impairment. It is characterized by the absence of Shiga toxin-producing bacteria as a triggering factor.
Dickenmann, Michael, Hirt-Minkowski, Patricia, Schifferli, Jürg A.   +2 more
core   +3 more sources

The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease [PDF]

, 2015
Atypical hemolytic uremic syndrome (aHUS) is characterized by complement attack against host cells due to mutations in complement proteins or autoantibodies against complement factor H (CFH).
Abarrategui-Garrido, Adams, Adrian Goldman, Arnab Bhattacharjee, Baker, Barbara Uzonyi, Bhattacharjee, Bhattacharjee, Blanc, Blaum, Castiblanco-Valencia, Dragon-Durey, Dragon-Durey, Dragon-Durey, Emsley, Eszter Trojnár, Eyler, Ferreira, Freddo, Fritzler, Goicoechea de Jorge, Harald Seeberger, Hebecker, Heinen, Herbert, Herbert, Hofer, Holmes, Jokiranta, Józsi, Józsi, Józsi, Kabsch, Kajander, Lehtinen, Manuelian, McCarthy, McCoy, Meri, Mihály Józsi, Moore, Morgan, Noris, Oppermann, Pangburn, Robert Kolodziejczyk, Roumenina, Satu Hyvärinen, Sinha, Stefanie Reuter, Strobel, Strobel, Sánchez-Corral, Sánchez-Corral, T. Sakari Jokiranta, Venables, Zipfel, Zipfel, Zoltán Prohászka, Ágnes Szilágyi   +59 more
core   +3 more sources

Complement Alternative Pathway Dominance in Atypical Hemolytic Uremic Syndrome Revealed by Endothelial Bioassays. [PDF]

Kidney Int Rep
Santarsiero D, Gastoldi S, Guaschino V, Bresin E, Pagani I, Pasini A, Romano E, Benigni A, Remuzzi G, Noris M, Aiello S.   +10 more
europepmc   +2 more sources

Does pre-incubation in selective-enrichment media improve the detection of diarrheagenic Escherichia coli using the RIDA®GENE PCR?

International Journal of Medical Microbiology, 2023
We aimed to investigate whether a selective pre-PCR enrichment step improves test performance of RIDA®GENE EHEC/EPEC to detect diarrheagenic Escherichia coli from stool samples.
Neele J. Froböse, Ioana D. Olaru, Julia Sophie Schneider, Wenlan Zhang, Alexander Mellmann, Franziska Schuler, Tobias Grebe, Frieder Schaumburg   +7 more
doaj   +1 more source

Complement‐driven hemolytic uremic syndrome

American journal of hematology/oncology, 2023
Overactivation of the complement alternative pathway drives the pathogenesis of primary atypical hemolytic uremic syndrome (aHUS). Genetically‐determined or acquired dysregulation of the complement is frequently identified in patients with aHUS ...
J. Léon, Marie-Bénédicte LeStang, R. Sberro-Soussan, A. Servais, D. Anglicheau, V. Frémeaux-Bacchi, J. Zuber   +6 more
semanticscholar   +1 more source

Atypical Hemolytic Uremic Syndrome Precipitated by Recurrent Pancreatitis

Annals of Internal Medicine: Clinical Cases, 2022
Atypical hemolytic uremic syndrome presents with negative direct antiglobulin test microangiopathic hemolytic anemia, acute kidney injury, and thrombocytopenia in the absence of diarrhea.
Nivine El-Hor, Kyle Kondrat, Suresh Balasubramanian   +2 more
doaj   +1 more source

Pharmacological Management of Atypical Hemolytic Uremic Syndrome in Pediatric Patients: Current and Future

Pediatric Drugs, 2023
Atypical hemolytic uremic syndrome is a thrombotic microangiopathy characterized by hemolysis, thrombocytopenia, and acute kidney injury, usually caused by alternative complement system overactivation due to pathogenic genetic variants or antibodies to ...
Evgenia Gurevich, D. Landau
semanticscholar   +1 more source

Hemolytic Uremic Syndrome: A Case Report

Journal of Nepal Medical Association, 2023
Thrombotic microangiopathy is a pathological condition comprised of microvascular thrombosis involving any body organ leading to thrombocytopenia, coombs-negative hemolytic anemia, and end-organ damage.
Sandesh Gaire, Mandira Shrestha, Chaitanya Darshan Bhattarai, Susajjan Dhungana, Surakshya Gyawali, Arun Bajgain   +5 more
doaj   +1 more source

Pneumococcal Hemolytic Uremic Syndrome in Children in Sweden. [PDF]

JAMA Netw Open
Hildenwall H, Georgieva V, Luthander J, Ladfors SW, Sartz L, Chromek M.   +5 more
europepmc   +2 more sources