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Atypical hemolytic uremic syndrome [PDF]

Orphanet Journal of Rare Diseases, 2011
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin-HUS and even if some authors include secondary aHUS due to Streptococcus pneumoniae
Frémeaux-Bacchi Véronique, Loirat Chantal   +1 more
doaj   +3 more sources

Pregnancy-Associated Atypical Hemolytic-Uremic Syndrome

American Journal of Perinatology Reports, 2016
Précis Introduction Early diagnosis of atypical uremic–hemolytic syndrome may be challenging during the puerperium period. Correct diagnosis and timely management are crucial to improve outcomes.
Antonio F. Saad, Jorge Roman, Aaron Wyble, Luis D. Pacheco   +3 more
doaj   +3 more sources

A Case of Severe Pre‐Eclampsia Complicated by HELLP Syndrome and Extensive Hepatic Infarction

Clinical Case Reports
Extensive hepatic infarction is a rare but potentially fatal complication of HELLP syndrome and is often difficult to recognize because of nonspecific clinical manifestations.
Tiange Xia, Fei Gao, Fengming Liang, Yang Shao   +3 more
doaj   +2 more sources

Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland [PDF]

Kidney International, 2017
Factor H autoantibodies can impair complement regulation, resulting in atypical hemolytic uremic syndrome, predominantly in childhood. There are no trials investigating treatment, and clinical practice is only informed by retrospective cohort ...
Vicky Brocklebank, Stephen D MarkS, Atif Awan   +2 more
exaly   +3 more sources

Atypical Hemolytic Uremic Syndrome Precipitated by Recurrent Pancreatitis

Annals of Internal Medicine: Clinical Cases, 2022
Atypical hemolytic uremic syndrome presents with negative direct antiglobulin test microangiopathic hemolytic anemia, acute kidney injury, and thrombocytopenia in the absence of diarrhea.
Nivine El-Hor, Kyle Kondrat, Suresh Balasubramanian   +2 more
doaj   +1 more source

Clostridioides difficile-Associated Atypical Hemolytic-Uremic Syndrome Successfully Treated With Eculizumab: A Case Report and Literature Review

Critical Care Explorations, 2021
BACKGROUND:. Clostridioides difficile infection is a rare precipitant for patients to develop atypical hemolytic-uremic syndrome, of which the pathogenesis remains unclear. Previous reports suggest activation of cytokine storm from binding of cyotoxins A
Michael N. Moulton, DO, Carl L. Kay, MD, Joshua T. Romain, MD, Benjamin D. Morrow, MD, Gilda M. Bobele, MD   +4 more
doaj   +1 more source

Hemolytic Uremic Syndrome: A Case Report

Journal of Nepal Medical Association, 2023
Thrombotic microangiopathy is a pathological condition comprised of microvascular thrombosis involving any body organ leading to thrombocytopenia, coombs-negative hemolytic anemia, and end-organ damage.
Sandesh Gaire, Mandira Shrestha, Chaitanya Darshan Bhattarai, Susajjan Dhungana, Surakshya Gyawali, Arun Bajgain   +5 more
doaj   +1 more source

Case series: coronavirus disease 2019 infection as a precipitant of atypical hemolytic uremic syndrome: two case reports

Journal of Medical Case Reports, 2021
Background Atypical hemolytic uremic syndrome is an exceedingly rare thrombotic microangiopathy caused by accelerated activation of the alternative complement pathway.
Christine J. Kurian, Zachary French, Patrick Kukulich, Matthew Lankiewicz, Sushil Ghimire, Omar H. Maarouf, Sanaa Rizk, Ruben Rhoades   +7 more
doaj   +1 more source

A novel missense mutation in complement factor I predisposes patients to atypical hemolytic uremic syndrome: a case report

Journal of Medical Case Reports, 2022
Background Atypical hemolytic uremic syndrome, also called the nondiarrheal form of hemolytic uremic syndrome, is a rare disease characterized by the triad of thrombocytopenia, Coomb’s test-negative microangiopathic hemolytic anemia, and acute renal ...
Xin Wei, Juan Li, Xiaojiang Zhan, Luxia Tu, Haowen Huang, Ying Wang   +5 more
doaj   +1 more source

Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

Brazilian Journal of Nephrology, 2020
Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement ...
Diana Carolina Bello-Marquez, John Fredy Nieto-Rios, Lina Maria Serna-Higuita, Alfonso Jose Gonzalez-Vergara   +3 more
doaj   +2 more sources