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An Atypical Cause Of Atypical Hemolytic Uremic Syndrome [PDF]
Marshall Journal of Medicine, 2016 Atypical hemolytic syndrome is an extremely rare, life threatening, progressive disease. Approximately one to two cases per million are seen annually in the US (3,4).
Abhinav Sharma +3 more
doaj +2 more sources
The Complement System in Post‐Transplant Kidney Injury
Organ Medicine, EarlyView.
Mengsi Hu
wiley +1 more source
Immunological Reviews, Volume 342, Issue 1, September 2026.ABSTRACT Post‐translational modifications (PTMs) of proteins are essential to maintain homeostasis as many cellular processes rely on reversible PTMs. However, several PTMs, particularly irreversible PTMs in the extracellular space, can contribute to tissue dysfunction, inflammation, and may even trigger the development of autoimmunity against PTM ...
Marleen M. J. van Greevenbroek +1 more
wiley +1 more source
Clinical Pharmacology: Advances and Applications, 2011 Maro Ohanian, Christian Cable, Kathleen HalkaDepartment of Hematology and Oncology, Scott and White Healthcare, The Texas A&M Health Science Center College of Medicine, Temple, TX, USAAbstract: This case report describes how eculizumab reversed ...
Ohanian M, Cable CC, Halka KK
doaj
Nephrology, Volume 31, Issue S2, September 2026.ABSTRACT The Thai Transplantation Society developed these clinical practice guidelines to establish a comprehensive standard for immunosuppressive therapy in adult kidney transplantation. While rooted in evidence‐based medicine, the objective of this document extends beyond local application, serving as a practical model for low‐to‐middle‐income ...
Suwasin Udomkarnjananun +12 more
wiley +1 more source
Exercise‐induced vasculitis with histological and genetic evidence of complement involvement
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Massimo Cugno +6 more
wiley +1 more source
Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Difficulties in diagnosing atypical hemolytic uremic syndrome
Сибирский научный медицинский журнал, 2020 The paper presents the case of clinical observation of a patient with atypical hemolytic-uremic syndrome (aHUS). aHUS is a disease characterized by an unfavorable prognosis (severe or catastrophic course with rapid development of terminal renal or multi ...
N. V. Fomina +5 more
doaj +1 more source
A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance
Annals of Clinical and Translational Neurology, Volume 13, Issue 7, Page 1518-1523, July 2026.ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley +1 more source
Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?
European Journal of Immunology, Volume 56, Issue 7, July 2026.Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni +4 more
wiley +1 more source