Results 41 to 50 of about 8,636 (197)

Hemolytic uremic syndrome related to Shiga-like toxin-producing Escherichia coli with encephalitis hiding a human herpesvirus-6 infection: a case report

Journal of Medical Case Reports, 2021
Background Cardiac and neurological involvement in hemolytic uremic syndrome are life-threatening complications. The most frequent complications of cardiac involvement in hemolytic uremic syndrome are myocarditis and cardiac dysfunction due to fluid ...
Sophie Mounier, Arthur Gavotto, Julie Tenenbaum, Pierre Meyer, Marc Fila, Julien Baleine   +5 more
doaj   +1 more source

Pregnancy-Induced Atypical Hemolytic Uremic Syndrome. [PDF]

Cureus
Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy that causes anemia, thrombocytopenia, and acute renal failure. In aHUS, a triggering event can lead to dysregulation of the complement immune system, leading to a cascade of events resulting in clot formation, capillary thrombosis, and renal dysfunction.
Den Boef A, Parekh S, O'Brien MC, Liu S, Jacob R.   +4 more
europepmc   +3 more sources

Atypical Hemolytic-Uremic Syndrome: Genetic Basis, Clinical Manifestations, and a Multidisciplinary Approach to Management [PDF]

, 2023
Keval Yerigeri,1 Saurav Kadatane,2 Kai Mongan,3 Olivia Boyer,4 Linda LG Burke,5 Sidharth Kumar Sethi,6 Christoph Licht,7 Rupesh Raina8 1Department of Internal Medicine-Pediatrics, Case Western Reserve University/The MetroHealth System, Cleveland, OH, USA;
Boyer O, Burke LL, Yerigeri K, Sethi SK, Kadatane S, Mongan K, Licht C, Raina R   +7 more
core  

Atypical hemolytic uremic syndrome

Journal of Allergy and Clinical Immunology
Hemolytic uremic syndromes are a heterogeneous group of conditions with differing underlying pathophysiology. These all result in pathologic features of thrombotic microangiopathy (TMA), which cause endothelial damage and organ injury. TMAs manifest with a microangiopathic hemolytic anaemia, thrombocytopenia, and commonly acute kidney injury.
Patrick R. Walsh, David Kavanagh
  +5 more sources

Purtscher-Like Retinopathy Associated with Atypical Hemolytic Uremic Syndrome [PDF]

, 2017
A 25-year-old woman presented with acute bilateral blurred vision and history of headache, dizziness, and syncope for three days. Her visual acuity was 20/60 in both eyes.
Mesut Ayer, Ozturk, Savaş, Ustaoglu, Melih, Solmaz, Nilgun, Savaş Öztürk, Ayer, Mesut, Feyza Önder, Nilgün Solmaz, Melih Ustaoğlu, Onder, Feyza   +9 more
core   +1 more source

Phenotypic manifestation of homozygous partial deletion of the chromosome 1 segment spanning CFHR3 region

Медицинская иммунология, 2020
This article presents two clinical cases of patients with a homozygous deletion of segment of chromosome 1, which covers regions of genes associated with complement factor H, in particular CFHR3.
I. A. Tuzankina, M. A. Bolkov, N. S. Zhuravleva, Yu. O. Vaseneva, Kh. Shinvari, O. V. Schipacheva   +5 more
doaj   +1 more source

Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome

Haematologica, 2017
Paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome are diseases of excess activation of the alternative pathway of complement that are treated with eculizumab, a humanized monoclonal antibody against the terminal complement ...
Xuan Yuan, Eleni Gavriilaki, Jane A. Thanassi, Guangwei Yang, Andrea C. Baines, Steven D. Podos, Yongqing Huang, Mingjun Huang, Robert A. Brodsky   +8 more
doaj   +1 more source

Use of eculizumab in pregnancy-associated atypical hemolytic uremic syndrome [PDF]

, 2018
Pregnancy-associated atypical hemolytic uremic syndrome (p-aHUS) is a rare disorder, with an estimated incidence of 1 in 25,000 pregnancies [Fakhouri F, Roumenina L, Provot F, Sallee M, Caillard S, Couzi L, et al.
Lawrence D. Platt, Neil S. Silverman, Meenal Misal, Megha Gupta, Christina S. Han   +4 more
core   +1 more source

Case Series of 3 Patients Diagnosed With Atypical Hemolytic Uremic Syndrome Successfully Treated With Steroids, Plasmapheresis, and Rituximab

Canadian Journal of Kidney Health and Disease, 2017
Rationale: Atypical hemolytic uremic syndrome, which has a high probability of chronic kidney disease, morbidity, and mortality, needs to be promptly recognized when patients present with microangiopathic hemolysis.
Jeffery M. Patterson, Lauren Bolster, Loree Larratt   +2 more
doaj   +1 more source

Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon? [PDF]

, 2012
BACKGROUND AND OBJECTIVES: Atypical hemolytic uremic syndrome is a disease associated with mutations in the genes encoding the complement regulators factors H and I.
Pietro Roversi, Hunze, EM, Christine M. Hayes, Timothy H. J. Goodship, Susan Lea, Bennaceur, K, Kevin J. Marchbank, Eva-Maria Hunze, Marchbank, KJ, Moore, Iain, Strain, Lisa, David Kavanagh, Ward, Roy, Marchbank, Kevin J., Lea, Susan, Moore, I, Nick Plant, Roy Ward, Corina Nailescu, Lea, S, Strain, L, Goodship, TH, Anderson, H, Karim Bennaceur, Plant, N, Bennaceur, Karim, Hayes, CM, Iain Moore, Hayes, Christine M., Pappworth, IY, Isabel Y. Pappworth, Kavanagh, David, Plant, Nick, Anderson, Holly, Nailescu, Corina, Hunze, Eva-Maria, Goodship, Timothy H. J., Nailescu, C, Pappworth, Isabel Y., Holly Anderson, Ward, R, Kavanagh, D, Roversi, Pietro, Lisa Strain, Roversi, P   +44 more
core   +1 more source