Results 31 to 40 of about 8,636 (197)

Overcoming technical challenges when treating atypical hemolytic uremic syndrome with therapeutic plasma exchange [PDF]

International Journal of Nephrology and Renovascular Disease, 2013
Edward Zimbudzi Department of Nephrology, Monash Health, Monash Medical Centre, Victoria, Australia Abstract: Atypical hemolytic uremic syndrome (aHUS) is a very rare, life-threatening, progressive disease that frequently has a genetic component and in ...
Zimbudzi E
doaj   +1 more source

Case Report: Lipoprotein Glomerulopathy Complicated by Atypical Hemolytic Uremic Syndrome. [PDF]

, 2021
Lipoprotein glomerulopathy (LPG) is a rare inherited disease caused by mutations in the APOE gene, encoding apolipoprotein E (apoE). Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) characterized by overactivation of the ...
Bresin, Elena, Hirt-Minkowski, Patricia, Neuhaus, Thomas J, Kollbrunner, Lara, Jehle, Andreas W, Sanz, Javier, Hopfer, Helmut   +6 more
core   +1 more source

Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome [PDF]

, 2021
Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement ...
Alfonso Jose Gonzalez-Vergara (10467822), John Fredy Nieto-Rios (5788220), Diana Carolina Bello-Marquez (4750176), Lina Maria Serna-Higuita (5788226)   +3 more
core   +1 more source

Delayed and sequencial hemolytic uremic syndrome as a complication of Gemcitabine therapy [PDF]

, 2022
Gemcitabine is a widely used drug in the treatment of diverse malignancies and its use has been approved by the US Food and Drug Administration. This drug has been associated with a rare adverse event, the Hemolytic Uremic Syndrome (HUS), characterized ...
Paulo Marcelo Gehm Hoff, Renata Colombo Bonadio, Paulo Henrique Amor-Divino, Rafaela Lopes da Silva Naves, Thaís Sampaio Corrêa de Almeida   +4 more
core   +1 more source

Transplantation in Atypical Hemolytic Uremic Syndrome [PDF]

Seminars in Thrombosis and Hemostasis, 2010
Atypical hemolytic uremic syndrome (aHUS) is a disease characterized by overactivation of complement. Recurrence following renal transplantation is determined by a genetic predisposition. Genetic screening of all individuals with aHUS should be performed prior to listing for transplantation. Individuals with isolated mutations in MCP have a low risk of
Kavanagh D, Richards A, Goodship T, Jalanko H   +3 more
openaire   +3 more sources

Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]

, 2010
Atypical haemolytic uraemic syndrome (aHUS) is associated with a poor prognosis with regard to survival at presentation, recovery of renal function and transplantation.
Sam Machin, ?, ?, Machin, Sam, Tim H. J. Goodship, Goodship, Tim H J, Stephen J. Wigmore, Taylor, C Mark, Wigmore, Stephen J, C. Mark Taylor   +8 more
core   +1 more source

The genetics of atypical hemolytic uremic syndrome [PDF]

Medizinische Genetik, 2018
Abstract Atypical hemolytic uremic syndrome (aHUS) is a disorder characterized by thrombocytopenia and microangiopathic hemolytic anemia due to endothelial injury. aHUS is felt to be caused by defective complement regulation due to underlying genetic mutations in complement regulators or activators, most often of the alternative pathway.
Feitz, W.JC., van de Kar, N.CA.J., Orth-Höller, D., van den Heuvel, L.PJ.W., Licht, C.   +4 more
openaire   +3 more sources

Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]

, 2010
Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Douglas, K.W., Green, R., Douglas, Kenneth W., Pollock, K.G.J., Pollock, Kevin G.J., Catlow, Jamie, Young, D., Catlow, J., Young, David, Green, Rachel   +9 more
core   +1 more source

Atypical hemolytic uremic syndrome [PDF]

Hematology, 2016
AbstractAtypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) that affects multiple organs and the kidneys in particular. aHUS can be sporadic or familial and is most commonly caused by dysregulation of the alternative complement pathway.
openaire   +2 more sources

Atypical Hemolytic Uremic Syndrome

Pediatric Clinics of North America, 2018
Atypical hemolytic uremic syndrome is a rare life-threatening disease of unregulated complement activation. Untreated, the prognosis is generally poor; more than one-half of patients die or develop end-stage renal disease within 1 year. Atypical hemolytic uremic syndrome is characterized by thrombotic microangiopathy with evidence of hemolysis ...
Bradley P. Dixon, Ralph A. Gruppo
  +7 more sources