Pediatric Atypical Hemolytic Uremic Syndrome Advances [PDF]
Atypical hemolytic uremic syndrome (aHUS) is a rare disorder characterized by dysregulation of the alternate pathway. The diagnosis of aHUS is one of exclusion, which complicates its early detection and corresponding intervention to mitigate its high ...
Rupesh Raina +9 more
doaj +3 more sources
Atypical Hemolytic-Uremic Syndrome: A Clinical Review [PDF]
Atypical hemolytic-uremic syndrome (HUS) is a rare life-threatening disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and ischemic injury to organs, especially the kidneys. Microvascular injury and thrombosis are the dominant
Nayer, Ali, Asif, Arif
core +3 more sources
An Atypical Cause Of Atypical Hemolytic Uremic Syndrome [PDF]
Atypical hemolytic syndrome is an extremely rare, life threatening, progressive disease. Approximately one to two cases per million are seen annually in the US (3,4).
Abhinav Sharma +3 more
doaj +2 more sources
Successful use of eculizumab to treat atypical hemolytic uremic syndrome in patients with inflammatory bowel disease [PDF]
Background Atypical hemolytic uremic syndrome is a rare group of disorders that have in common underlying complement amplifying conditions. These conditions can accelerate complement activation that results in a positive feedback cycle.
Ramy M. Hanna +8 more
doaj +3 more sources
Atypical hemolytic-uremic syndrome, manifesting without thrombocytopenia (clinical case) [PDF]
Background. Atypical hemolytic uremic syndrome is an ultra-rare (orphan) disease from the group of thrombotic microangiopathies of progressive course, which is caused by uncontrolled activation of the alternative complement pathway of hereditary or ...
A.A. Dyachkova +3 more
doaj +2 more sources
Eculizumab experience in an adult patient with atypical hemolytic uremic syndrome [PDF]
Atypical hemolytic-uremic syndrome is a disease characterized by nonimmune hemolytic anemia, thrombocytopenia, and renal failure. In this study, we present a case of a patient with atypical hemolytic-uremic syndrome treated successfully with eculizumab ...
Funda Sari +6 more
doaj +2 more sources
SUCCESSFUL TREATMENT FOR ATYPICAL HEMOLYTIC UREMIC SYNDROME IN A PUERPERA [PDF]
Objective: to show the problems of differential diagnosis and treatment of atypical hemolytic-uremic syndrome in a 23-year-old patient.Results. Eculizumab (Soliris), (Alexon Pharmaceuticals Inc., USA) that is a glycosylated humanized monoclonal antibody ...
O. N. Ulitkina +4 more
doaj +3 more sources
Difficulties in diagnosing atypical hemolytic uremic syndrome [PDF]
The paper presents the case of clinical observation of a patient with atypical hemolytic-uremic syndrome (aHUS). aHUS is a disease characterized by an unfavorable prognosis (severe or catastrophic course with rapid development of terminal renal or multi ...
N. V. Fomina +5 more
doaj +2 more sources
Atypical hemolytic uremic syndrome: a brief review [PDF]
Atypical hemolytic uremic syndrome (aHUS) is a disease characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury.
Kuixing Zhang +3 more
doaj +5 more sources
Eculizumab safely reverses neurologic impairment and eliminates need for dialysis in severe atypical hemolytic uremic syndrome [PDF]
Maro Ohanian, Christian Cable, Kathleen HalkaDepartment of Hematology and Oncology, Scott and White Healthcare, The Texas A&M Health Science Center College of Medicine, Temple, TX, USAAbstract: This case report describes how eculizumab reversed ...
Ohanian M, Cable CC, Halka KK
doaj +3 more sources

