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Nephron, 1973
The clinical and pathological characteristics of the acute stage of the HUS are described on the basis of 678 patients and the study of 52 autopsies and 3 kidney biopsies.
Sojo Et +4 more
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The clinical and pathological characteristics of the acute stage of the HUS are described on the basis of 678 patients and the study of 52 autopsies and 3 kidney biopsies.
Sojo Et +4 more
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The Hemolytic Uremic Syndromes [PDF]
, 1989 This paper is about a number of disorders occurring in children and adults that, although they have different etiologies and variable clinical expression, share three constant features: acquired hemolytic anemia, thrombocytopenia and renal damage, and one common histological lesion mostly referred to as thrombotic microangiopathy, a term introduced by ...
W. Proesmans, R. Eeckels
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Current Problems in Pediatrics, 1993
HUS is one of the most common causes of acute renal failure in childhood. D+ HUS is the most common form and usually follows an episode of hemorrhagic colitis due to VTEC or S. dysenteriae type 1. The SLT elaborated by these organisms is responsible for the endothelial damage that is the initial insult in the pathogenesis of the acute renal failure ...
Bernard S. Kaplan +2 more
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HUS is one of the most common causes of acute renal failure in childhood. D+ HUS is the most common form and usually follows an episode of hemorrhagic colitis due to VTEC or S. dysenteriae type 1. The SLT elaborated by these organisms is responsible for the endothelial damage that is the initial insult in the pathogenesis of the acute renal failure ...
Bernard S. Kaplan +2 more
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Pediatric Clinics of North America, 1976
It is becoming increasingly apparent that the hemolytic uremic syndrome is a heterogenic and heterogeneous syndrome. There has been a dramatic reduction in the number of patients who die in the acute phase of the illness. Any claims for the use of heparin and streptokinase must be measured against the improved results which are now being obtained with ...
Bernard S. Kaplan +2 more
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It is becoming increasingly apparent that the hemolytic uremic syndrome is a heterogenic and heterogeneous syndrome. There has been a dramatic reduction in the number of patients who die in the acute phase of the illness. Any claims for the use of heparin and streptokinase must be measured against the improved results which are now being obtained with ...
Bernard S. Kaplan +2 more
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The hemolytic uremic syndromes
Current Opinion in Critical Care, 2005Recent studies have provided a better understanding of the molecular mechanisms responsible for hemolytic uremic syndromes. In this review, we summarize biochemical and genetic data that may lead to new clinical approaches.The structures and modes of action of Shiga toxins have been deciphered.
Jessica Caprioli +2 more
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The Indian Journal of Pediatrics, 1984
There have been major advances in the understanding of pathogenesis and management of hemolytic uremic syndrome in the last decade. Since the consensus paper published in 2009 by the European Pediatric Study Group in 2009, there have been four prospective trials and multiple case reports on effective terminal blockade with Eculizumab, an international ...
A K Shah, K R Sheth
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There have been major advances in the understanding of pathogenesis and management of hemolytic uremic syndrome in the last decade. Since the consensus paper published in 2009 by the European Pediatric Study Group in 2009, there have been four prospective trials and multiple case reports on effective terminal blockade with Eculizumab, an international ...
A K Shah, K R Sheth
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Pediatrics in Review, 2001
The hemolytic-uremic syndrome (HUS) has been recognized for more than 45 years and consists of the combination of hemolytic anemia, thrombocytopenia, and acute renal failure. HUS occurs predominantly in children younger than 4 years of age. It is the most frequent cause of acute renal failure in children.
Frank G. Boineau, James J. Corrigan
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The hemolytic-uremic syndrome (HUS) has been recognized for more than 45 years and consists of the combination of hemolytic anemia, thrombocytopenia, and acute renal failure. HUS occurs predominantly in children younger than 4 years of age. It is the most frequent cause of acute renal failure in children.
Frank G. Boineau, James J. Corrigan
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The Journal of Pediatrics, 1964
The combination of acute renal failure, thrombocytopenia, and hemolytic anemia associated with distorted erythrocytes (“burr” cells) constitutes the hemolytic-uremic syndrome. These observations of the natural history of 58 affected infants and children represent the largest single group studied.
Carlos A. Gianantonio +4 more
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The combination of acute renal failure, thrombocytopenia, and hemolytic anemia associated with distorted erythrocytes (“burr” cells) constitutes the hemolytic-uremic syndrome. These observations of the natural history of 58 affected infants and children represent the largest single group studied.
Carlos A. Gianantonio +4 more
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New England Journal of Medicine, 1969
The association of acute hemolytic anemia, thrombocytopenia and renal failure was described by Casser et al.1 in 1955. Since that time, several hundred cases have been reported, mainly in children. In adults, the hemolytic-uremic syndrome is often associated with pregnancy.
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The association of acute hemolytic anemia, thrombocytopenia and renal failure was described by Casser et al.1 in 1955. Since that time, several hundred cases have been reported, mainly in children. In adults, the hemolytic-uremic syndrome is often associated with pregnancy.
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The Hemolytic-Uremic Syndrome Is a Syndrome
New England Journal of Medicine, 1978The article in this week's issue of the Journal by Koster and his colleagues raises important questions not only about the pathogenesis of the hemolytic-uremic syndrome but, perhaps more importantl...
Keith N. Drummond, Bernard S. Kaplan
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