Results 61 to 70 of about 59,490 (296)

Hemolytic uremic syndrome with multiple organ involvement secondary to complement factor H p.Arg1215X mutation

open access: yesThe Turkish Journal of Pediatrics, 2017
Complement mediated hemolytic uremic syndrome which is caused by excessive activation of the alternative complement system is a thrombotic microangiopathy.
Osman Yeşilbaş   +5 more
doaj   +1 more source

Thrombotic microangiopathy and associated renal disorders [PDF]

open access: yes, 2012
Thrombotic microangiopathy (TMA) is a pathological process involving thrombocytopenia, microangiopathic haemolytic anaemia and microvascular occlusion.
Barbour, T   +3 more
core   +1 more source

Pregnancy-Associated Atypical Hemolytic Uremic Syndrome

open access: yesObstetrics and Gynecology, 2019
Pregnancy-associated atypical hemolytic uremic syndrome usually presents in the postpartum period, often after a pregnancy complication, and eculizumab is effective for achieving disease remission.
Megha Gupta   +2 more
semanticscholar   +1 more source

The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506: Clinical significance and comparison with cyclosporine [PDF]

open access: yes, 1993
The histopathological changes in 51 renal allograft biopsies from patients immunosuppressed with FK506 were compared with those seen in 30 needle biopsies obtained from patients on cyclosporine.
Demetris, AJ   +4 more
core   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova   +2 more
wiley   +1 more source

Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome

open access: yesHaematologica, 2017
Paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome are diseases of excess activation of the alternative pathway of complement that are treated with eculizumab, a humanized monoclonal antibody against the terminal complement ...
Xuan Yuan   +8 more
doaj   +1 more source

Shiga toxin/verocytotoxin-producing Escherichia coli infections: practical clinical perspectives [PDF]

open access: yes, 2014
Escherichia coli strains that produce Shiga toxins/verotoxins are rare, but important, causes of human disease. They are responsible for a spectrum of illnesses that range from the asymptomatic to the life-threatening hemolytic-uremic ...
Davis, T. K   +2 more
core   +2 more sources

Eculizumab in atypical hemolytic uremic syndrome: strategies toward restrictive use

open access: yesPediatric nephrology (Berlin, West), 2018
With the introduction of the complement C5-inhibitor eculizumab, a new era was entered for patients with atypical hemolytic uremic syndrome (aHUS).
K. Wijnsma   +3 more
semanticscholar   +1 more source

Concurrent Scrub Typhus, Dengue, and Leptospirosis: A Rare Triple Co‐Infection: A Case Report and Comprehensive Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT In endemic areas, acute undifferentiated febrile illness has a wide differential with overlapping features that can lead to misdiagnosis. Although triple co‐infection with scrub typhus, dengue, and leptospirosis is extremely rare, high clinical suspicion and early detection are vital to avoid delayed treatment, multi‐organ dysfunction, and ...
Sulav Kumar Jha   +5 more
wiley   +1 more source

Pregnancy-Associated Atypical Hemolytic-Uremic Syndrome

open access: yesAmerican Journal of Perinatology Reports, 2016
Précis Introduction Early diagnosis of atypical uremic–hemolytic syndrome may be challenging during the puerperium period. Correct diagnosis and timely management are crucial to improve outcomes.
Antonio F. Saad   +3 more
doaj   +1 more source

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