Results 61 to 70 of about 1,197,936 (217)

Unsupervised Global CBC/RUO/CPD Phenotyping Identifies Haematological Clusters Enriched for Thrombocytopenia Severity and Mechanisms

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Thrombocytopenia has heterogeneous mechanisms, including peripheral destruction, consumption, and reduced marrow production. This study developed an unsupervised global complete blood count/research‐use‐only/cell population data (CBC/RUO/CPD) phenotyping model and evaluated post hoc whether thrombocytopenia severity and clinically
Mohammad A. Altememi, Emmanuel J. Favaloro, Md Zahidul Islam, Sara Ng, Danny Hsu, Abishek B. Santhakumar   +5 more
wiley   +1 more source

Pregnancy-associated hemolytic uremic syndrome

Saudi Journal of Kidney Diseases and Transplantation, 2020
Pregnancy-associated hemolytic uremic syndrome (P-aHUS) is not an uncommon condition. It is considered a medical emergency that is associated with a high risk of mortality and serious morbidity.
Sami Alobaidi, Ammar AlDabbagh, Amany Alamoudi, Murad Almowarey, Ahmed Akl   +4 more
doaj   +1 more source

Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors

Internal Medicine Journal, EarlyView.
Abstract Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence‐based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting.
Katherine A. Buzzard, Michael Barnett, Heidi Beadnall, Mirasol Forcadela, Lesley‐Ann Hall, Victoria G. Hall, Todd Hardy, Danny Hsu, Paul Kinsella, Mastura Monif, Sudarshini Ramanathan, Stephen W. Reddel, Sean Riminton, Douglas F. Johnson   +13 more
wiley   +1 more source

Síndrome hemolítico-urémico.

Acta Médica Portuguesa, 1999
The microangiopathic thrombotic syndromes--thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS)--are characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal dysfunction, fever and central nervous system ...
P A Rodrigues, J Machado, O Cardoso, J Cruz, F Carvalho, M da Costa, R Proença   +6 more
doaj   +1 more source

Glycated albumin: An old yet new biomarker in people with diabetes and the potential for novel applications

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Glycated albumin (GA), the product of nonenzymatic glycation of serum albumin, reflects the mean glucose levels over the preceding approximately 2 weeks, bridging the gap between daily self‐monitoring of blood glucose and the roughly 3‐month window covered by glycated hemoglobin (HbA1c) measurement.
Masakazu Aihara, Naoto Kubota
wiley   +1 more source

Successful use of eculizumab to treat atypical hemolytic uremic syndrome in patients with inflammatory bowel disease

Thrombosis Journal, 2019
Background Atypical hemolytic uremic syndrome is a rare group of disorders that have in common underlying complement amplifying conditions. These conditions can accelerate complement activation that results in a positive feedback cycle.
Ramy M. Hanna, Noah Merin, Richard M. Burwick, Lama Abdelnour, Umut Selamet, Beshoy Yanny, Patrick Bui, Mary Fouad, Ira Kurtz   +8 more
doaj   +1 more source

Phenotypic manifestation of homozygous partial deletion of the chromosome 1 segment spanning CFHR3 region

Медицинская иммунология, 2020
This article presents two clinical cases of patients with a homozygous deletion of segment of chromosome 1, which covers regions of genes associated with complement factor H, in particular CFHR3.
I. A. Tuzankina, M. A. Bolkov, N. S. Zhuravleva, Yu. O. Vaseneva, Kh. Shinvari, O. V. Schipacheva   +5 more
doaj   +1 more source

The Complement System in Post‐Transplant Kidney Injury

Organ Medicine, EarlyView.
Mengsi Hu
wiley   +1 more source

Cancer‐Related Microangiopathic Haemolytic Anemia Revealing Occult Metastatic Gastrointestinal Signet‐Ring Cell Carcinoma: A Clinicopathological Case Report and Practical Differential Diagnostic Approach

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This case highlights key laboratory red flags and a failure to respond to standard treatment, both of which should prompt urgent investigation for occult malignancy in patients presenting with cancer‐related microangiopathic hemolytic anemia (CR‐MAHA).
Danijela Jovanovic, Snezana Sretenovic, Dalibor Jovanovic, Milena Ilic, Predrag Djurdjevic   +4 more
wiley   +1 more source

When Liver Disease Misleads the Diagnosis: Two Cases of TAFRO Syndrome With Porto‐Sinusoidal Vascular Disease

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Background TAFRO syndrome is a rare inflammatory disorder whose hepatic manifestations may mimic decompensated cirrhosis. Cases: We report two women with TAFRO syndrome associated with portal‐sinusoidal vascular disorder (PSVD), a rare cause of non‐cirrhotic portal hypertension. In both cases, liver biopsy excluded cirrhosis and confirmed PSVD.
Laura Dassy, Fanny Poletti, Kaoutar Hafraoui, Marie Lejeune, Joan Somja, Patrick Collins, Julien Guiot, Ivan Theate, Jo Caers, Jean Delwaide, Astrid Marot, Virginie Putzeys, Gaëlle Vertenoeil   +12 more
wiley   +1 more source