Results 271 to 280 of about 11,283,851 (345)

2D copper nanozyme patches facilitate bone regeneration via interfacial modulation of osteoclast‐osteoblast dynamics

open access: yesBMEMat, EarlyView.
This study develops a nano‐enzyme patch (ezPatch) targeting bone interfaces. Utilizing ligand‐to‐metal charge transfer (LMCT) catalysis and bone‐targeting ligands on copper nanosheets, ezPatch simultaneously scavenges reactive oxygen species (ROS) and generates oxygen in situ at bone‐losing sites.
Yi Chen   +12 more
wiley   +1 more source

Multiquery Similarity Searching Models: An Alternative Approach for Predicting Hemolytic Activity from Peptide Sequence

open access: green
Kevin Castillo-Mendieta   +7 more
openalex   +2 more sources
Some of the next articles are maybe not open access.

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Hemolytic Activity of Antimicrobial Peptides

Methods in molecular biology, 2016
For antimicrobial peptides to be interesting for systemic applications, they must show low toxicity against erythrocytes. In this chapter, we describe a protocol for measuring the ability of AMPs to lyse human red blood cells, using melittin as positive control.
Oddo, Alberto, Hansen, Paul Robert
openaire   +3 more sources

The effect of structural modification of antimicrobial peptides on their antimicrobial activity, hemolytic activity, and plasma stability

Journal of Peptide Science, 2021
In this article, a series of modifications were made on an antimicrobial peptide F2,5,12W, including altering the amino acid sequence, introducing cysteine and other typical amino acids, developing peptide dimers via disulfide bonds, and conjugating with
Taoran Wang   +8 more
semanticscholar   +1 more source

New indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity.

Peptides, 2020
To create a broad-spectrum peptide biocide, we synthesized 45 analogs of antimicrobial peptide indolicidin (H-Ile-Leu-Pro-Trp-Lys-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-NH2).
M. Smirnova   +8 more
semanticscholar   +1 more source

HLPpred-Fuse: improved and robust prediction of hemolytic peptide and its activity by fusing multiple feature representation

Bioinform., 2020
MOTIVATION Therapeutic peptides failing at clinical trials could be attributed to their toxicity profiles like hemolytic activity, which hamper further progress of peptides as drug candidates.
M. Hasan   +5 more
semanticscholar   +1 more source

Hemolytic activity of Serratia marcescens

Archives of Microbiology, 1985
A cell-bound hemolytic activity was found in several strains of Serratia marcescens. One Serratia cell per ten erythrocytes was sufficient to cause complete lysis of human erythrocytes within 2 h in the liquid assay. The hemolytic activity resided in the membrane fraction and could be inactivated by incubating cells with proteases.
V, Braun   +3 more
openaire   +2 more sources

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