Clinical characteristics and outcome of patients with autoimmune hemolytic anemia (AIHA) uniformly defined as primary by a diagnostic work-up [PDF]
Primary autoimmune hemolytic anemia (P-AIHA) is a relatively uncommon and hetereogeneous disease characterized by the destruction of red blood cells due to anti-erythrocyte autoantibodies (AeAbs) in the absence of an associated disease [1–3].
ARMIENTO, DANIELE+15 more
core +1 more source
Mixed autoimmune hemolytic anemia in a 2-year-old girl
Immune hemolytic anemia is diagnosed when it exhibits the clinical symptoms and laboratory findings of hemolytic anemia, such as pallor, jaundice, anemia, high indirect bilirubin, increased reticulocyte count, and a positive direct antiglobulin test ...
Asim Abdullah Alamri+5 more
doaj +1 more source
Iron metabolism of intestinal mucosa in various blood diseases [PDF]
For the investigation of iron metabolism in the intestinal mucosa in various blood diseases, intestinal biopsy (duodenum) was performed on 10 healthy controls and 35 cases with various blood diseases.
Kimura, Ikuro+2 more
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When the environment and mutations affect organ systems [PDF]
Atypical hemolytic uremic syndrome (aHUS) is a rare thrombotic microangiopathy (TMA) with a genetic predisposition. Like other TMAs, it presents clinically with thrombocytopenia and microangiopathic hemolytic anemia, which is accompanied by disruption of
Abu Ghanimeh, Mouhanna+3 more
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ACVIM consensus statement on the diagnosis of immune‐mediated hemolytic anemia in dogs and cats
Immune‐mediated hemolytic anemia (IMHA) is an important cause of morbidity and mortality in dogs. IMHA also occurs in cats, although less commonly.
O. Garden+21 more
semanticscholar +1 more source
Bovine hemolytic anemia has a negative impact on animal welfare and productivity due to its associated clinical symptoms. Hemolysis is generally known to cause reticulocytosis, increased indirect bilirubin, decreased concentration of haptoglobin, and ...
Youngwoo Jung+8 more
doaj +1 more source
ACVIM consensus statement on the treatment of immune‐mediated hemolytic anemia in dogs
Immune‐mediated hemolytic anemia (IMHA) causes severe anemia in dogs and is associated with considerable morbidity and mortality. Treatment with various immunosuppressive and antithrombotic drugs has been described anecdotally and in previous studies ...
J. Swann+7 more
semanticscholar +1 more source
Aplastic Crisis as Primary Manifestation of Systemic Lupus Erythematosus [PDF]
Aplastic crisis is an unusual feature of systemic lupus erythematosus (SLE). We report the case of a 54-year-old woman presenting with both (extravascular) Coombs-positive hemolytic anemia and laboratory findings of bone marrow hyporegeneration with ...
Alger M+23 more
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Autoimmune hemolytic anemia (AIHA) may be the first manifestation of systematic lupus erythematosus (SLE). Antierythrocyte antibodies in SLE are mainly warm-type Immunoglobulin G (IgG), but mixed-type AIHA is also reported.
Vajihe Marsusi+5 more
doaj
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency [PDF]
Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, clinically managed by maintaining ...
Ionova, Tatyana+3 more
core +2 more sources