Results 41 to 50 of about 60,975 (303)

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Microangiopathic Hemolytic Anemia

, 2014
This image demonstrates the presence of schistocytes and decreased platelets in microangiopathic hemolytic ...
Fraser, Marion
core   +1 more source

Hemolytic, Anemia-Inducing Substance in Cancer Tissue [PDF]

, 1960
In 1959 we discovered that a hemolytic, anemia-inducing substance is produced in the animals exposed to X-rays. Since then we have found that when this substnce is injeted intravenously into animals, there occur disturbances in the blood, spleen and bone
Nobuki, Sigeo, Siaku, Takeru, Akagi, Keiko, Tanimoto, Junichi, Keiko AKAGI, Kojima, Sumikazu, Siaku, Midori, Midori SIAKU, Michio YAMAMOTO, Takeru SIAKU, Yamamoto, Michio, Iguti, Yosiko, Yosiko IGUTI, Junichi TANIMOTO, Sigeo NOBUKI, Sumikazu KOJIMA   +15 more
core   +1 more source

Metformin-Induced Hemolytic Anemia [PDF]

Medical Principles and Practice, 2013
<b><i>Objective:</i></b> To report a rare side effect of metformin, an oral antidiabetic drug that is used for the treatment of type 2 diabetes mellitus. <b><i>Clinical Presentation and Intervention:</i></b> A 17-year-old boy was hospitalized for receiving acute lymphoblastic leukemia treatment that was ...
Kirkiz, Serap, Yarali, Nese, Tunc, Bahattin, Arman Bilir, Ozlem   +3 more
openaire   +4 more sources

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Better 10‐Year Cerebrovascular Outcome After Transplant Than on Standard‐Care in Sickle Cell Anemia: DREPAGREFFE Trial

American Journal of Hematology, EarlyView.
ABSTRACT Management of cerebral vasculopathy in sickle cell anemia (SCA) includes standard‐care, that is, chronic transfusion (CT) or hydroxyurea, and hematopoietic cell transplantation (HCT). DREPAGREFFE‐1 (December 2010/June 2013), a French multicenter trial, was the first prospective trial comparing standard‐care to match sibling donor (MSD)‐HCT in ...
Francoise Bernaudin, Suzanne Verlhac, Elisabeth Ducros‐Miralles, Cécile Arnaud, Isabelle Genty, Marie Petras, Catherine Paillard, Gonzalo De Luna, Benoit Meunier, Isabelle Thuret, Annie Kamdem, Corinne Pondarré, Giovanna Cannas, Christelle Chantalat‐Auger, Nadia Firah, Sophie Pertuisel, Laure Joseph, Florence Missud, Mariane de Montalembert, Corinne Guitton, Claire Pluchart, Valentine Brousse, Monique Elmaleh, Vincent Gajdos, Emmanuella Leveillé, Ekaterina Belozertseva, Mabel Gaba, Catherine Poirot, Virginie Barraud‐Lange, Philippe Chadebech, France Pirenne, Myriam Bernaudin, Bénédicte Neven, Pierre Frange, Marie Angoso, Karima Yakouben, Bénédicte Bruno, Nathalie Dhédin, Jean‐Hugues Dalle, Regis Peffault Delatour, Camille Jung   +40 more
wiley   +1 more source

A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report

Frontiers in Immunology
Contrast medium is frequently associated with allergic reactions and kidney dysfunction. However, contrast media can induce hemolytic anemia with a broad spectrum of hemolytic manifestations.
Sabine Hermann, Karina Althaus, Migdat Mustafi, Beate Mayer, Peter Rosenberger, Helene Anna Haeberle, Alice Bernard   +6 more
doaj   +1 more source

Cold agglutinin-induced hemolytic anemia during room temperature fluid resuscitation: a case report

Journal of Medical Case Reports, 2021
Background Cold agglutinin disease can cause the agglutination of red blood cells and hemolytic anemia due to cold temperature. Herein, we report a case of progressive hemolytic anemia due to cold agglutinin disease during fluid resuscitation and in the ...
Yosuke Kawai, Miyoshi Deguchi, Naoko Mizouchi, Satoru Yoshida, Ken Kumagai, Yasuo Hirose   +5 more
doaj   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Case Report: Acute hepatitis A virus infection presenting with direct antiglobulin test-negative autoimmune hemolytic anemia and α-thalassemia trait [version 2; peer review: 2 approved, 1 approved with reservations]

F1000Research
Reports from the literature have discussed patients presenting Hepatitis A virus infection with hemolytic anemia, specifically with glucose-6-phosphate dehydrogenase deficiency. However, autoimmune hemolytic anemia (AIHA) has been rarely reported.
Habiba Debbabi, Eya Chakroun, Haythem Yacoub, Nadia Maamouri, Hela Kchir, Hajer Hassine, Dhouha Cherif   +6 more
doaj   +1 more source