Autoimmune hemolytic anemia (AHA) is characterized by the production of Coombs' antibodies, which are responsible for the destruction of red blood cells (RBCs). Analysis of both monoclonal anti-RBC autoantibodies derived from autoimmune New Zealand black mice and transgenic mice expressing a pathogenic IgM anti-RBC autoantibody has considerably ...
openaire +3 more sources
Problem of the diagnosis of acquired hemolytic anemia in childhood
Autoimmune hemolytic anemia is a heterogeneous group of diseases that are associated with decompensated acquired hemolysis. Autoimmune hemolytic anemia in children is most commonly observed after a viral illness. However, it is quite a rare disorder with
S.O. Nykytyuk +4 more
doaj +1 more source
Thrombotic Thrombocytopenic Purpura, Moschcowitz Syndrome [PDF]
The authors present a case of a 16-year-old boy, who was referred to the hospital due to thrombocytopenia, anemia, proteinuria and hyperbilirubinemia. Based on the clinical picture and the laboratory data, thrombotic thrombocytopenic purpura (TTP) was ...
Czinyéri, Judit +4 more
core
Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report
Autoimmune hemolytic anemia is a rare hematologic entity in children. Etiologies are mainly viruses or bacteria. We describe here a case of severe warm autoimmune hemolytic anemia (IgG- and C3d-positive direct antiglobulin test) in an immunocompetent 6 ...
Hassan K. Khalifeh +2 more
doaj +1 more source
A case of asymptomatic pancytopenia with clinical features of hemolysis as a presentation of pernicious anemia [PDF]
Pernicious anemia is an autoimmune disease with a variety of clinical presentations. We describe a case of pernicious anemia presenting with pancytopenia with hemolytic features.
Venkateswara K. Kollipara +3 more
doaj +1 more source
Mycoplasma suis infection in suckling pigs on a Belgian farm [PDF]
Mycoplasma suis (formerly known as Eperythrozoon suis) is an epicellular bacterium that affects porcine red blood cells. M. suis infections occur worldwide and are associated with weakness and anemia in suckling and weaned pigs, and reproductive ...
De Busser, Emily Valerie +5 more
core +1 more source
Characterisation of the Immunophenotype of Dogs with Primary Immune-Mediated Haemolytic Anaemia [PDF]
Immune-mediated haemolytic anaemia (IMHA) is reported to be the most common autoimmune disease of dogs, resulting in significant morbidity and mortality in affected animals.
A Corato +65 more
core +11 more sources
Rh Negative Status and Isoimmunization Update: A Case-Based Approach to Care [PDF]
Prior to the 1970s and the advent of Rho (D) immune globulin (RIG) for Rh negative women, hemolytic disease of the newborn led to morbidity, long-term disabilities, and mortality.
Hanson, Lisa +3 more
core +1 more source
Oncologic Emergencies: Immune-Based Cancer Therapies and Complications [PDF]
Cancer therapies have undergone several recent advancements. Current cancer treatments include immune-based therapies comprised of checkpoint inhibitors, and adoptive immunotherapy; each treatment has the potential for complications that differ from ...
Brém, Elizabeth +2 more
core
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency [PDF]
Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, clinically managed by maintaining ...
Ionova, Tatyana +3 more
core +2 more sources

