Results 51 to 60 of about 97,351 (209)
Sublytic Terminal Complement Components Induce Eryptosis in Autoimmune Haemolytic Anaemia Related to IgM Autoantibodies [PDF]
BACKGROUND/AIMS: Eryptosis, the suicidal death of red blood cells (RBCs), is characterized by phosphatidylserine (PS) exposure at the cell surface. It can be catalysed by a variety of abnormal conditions and diseases.
Balola, Abdelwahab Hassan Ahmed +3 more
core +1 more source
Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report
Autoimmune hemolytic anemia is a rare hematologic entity in children. Etiologies are mainly viruses or bacteria. We describe here a case of severe warm autoimmune hemolytic anemia (IgG- and C3d-positive direct antiglobulin test) in an immunocompetent 6 ...
Hassan K. Khalifeh +2 more
doaj +1 more source
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency [PDF]
Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, clinically managed by maintaining ...
Ionova, Tatyana +3 more
core +2 more sources
Rh Negative Status and Isoimmunization Update: A Case-Based Approach to Care [PDF]
Prior to the 1970s and the advent of Rho (D) immune globulin (RIG) for Rh negative women, hemolytic disease of the newborn led to morbidity, long-term disabilities, and mortality.
Hanson, Lisa +3 more
core +1 more source
Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes. [PDF]
BackgroundA growing number of realistic in silico models of metabolic functions are being formulated and can serve as 'dry lab' platforms to prototype and simulate experiments before they are performed.
Jamshidi, Neema, Palsson, Bernhard O
core +3 more sources
The array of diagnostic workup for pyrexia of unknown origin (PUO) generally revolves in searching for infections, inflammatory/autoimmune, and endocrine etiologies.
Vikas A Mishra +2 more
doaj +1 more source
The global emergence of clinical diseases caused by enterohemorrhagic Escherichia coli (EHEC) is an issue of great concern. EHEC release Shiga toxins (Stxs) as their key virulence factors, and investigations on the cell-damaging mechanisms toward target ...
Johanna Detzner +2 more
doaj +1 more source
Summary: Hemolytic anemia is a collection of diseases resulting from an exaggeration of the lysis of red blood cells. Hemolysis can be caused by extravacular aggression by drugs or other toxic or by antibodies againt red blood cell.
JAMILA ELHOUDZI
doaj
Tegsedi-Induced Warm Antibody Autoimmune Hemolytic Anemia
Autoimmune hemolytic anemia is a hemolytic disorder in which antibodies attack erythrocytes, causing their destruction. Many medications have been linked to autoimmune hemolytic anemia, such as antibiotics, chemotherapy agents, and nonsteroidal anti ...
Mariela Di Vanna +3 more
doaj +1 more source
Background Drug induced immune hemolytic anemia (DIIHA) is a rare complication and often underdiagnosed. DIIHA is frequently associated with a bad outcome, including organ failure and even death. For the last decades, ceftriaxone has been one of the most
Hans Benno Leicht +5 more
doaj +1 more source

