Results 51 to 60 of about 97,351 (209)

Sublytic Terminal Complement Components Induce Eryptosis in Autoimmune Haemolytic Anaemia Related to IgM Autoantibodies [PDF]

open access: yes, 2019
BACKGROUND/AIMS: Eryptosis, the suicidal death of red blood cells (RBCs), is characterized by phosphatidylserine (PS) exposure at the cell surface. It can be catalysed by a variety of abnormal conditions and diseases.
Balola, Abdelwahab Hassan Ahmed   +3 more
core   +1 more source

Infantile Cytomegalovirus-Associated Severe Warm Autoimmune Hemolytic Anemia: A Case Report

open access: yesChildren, 2017
Autoimmune hemolytic anemia is a rare hematologic entity in children. Etiologies are mainly viruses or bacteria. We describe here a case of severe warm autoimmune hemolytic anemia (IgG- and C3d-positive direct antiglobulin test) in an immunocompetent 6 ...
Hassan K. Khalifeh   +2 more
doaj   +1 more source

Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency [PDF]

open access: yes, 2018
Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, clinically managed by maintaining ...
Ionova, Tatyana   +3 more
core   +2 more sources

Rh Negative Status and Isoimmunization Update: A Case-Based Approach to Care [PDF]

open access: yes, 2003
Prior to the 1970s and the advent of Rho (D) immune globulin (RIG) for Rh negative women, hemolytic disease of the newborn led to morbidity, long-term disabilities, and mortality.
Hanson, Lisa   +3 more
core   +1 more source

Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes. [PDF]

open access: yes, 2009
BackgroundA growing number of realistic in silico models of metabolic functions are being formulated and can serve as 'dry lab' platforms to prototype and simulate experiments before they are performed.
Jamshidi, Neema, Palsson, Bernhard O
core   +3 more sources

Vitamin B12 and vitamin D deficiencies: An unusual cause of fever, severe hemolytic anemia and thrombocytopenia

open access: yesJournal of Family Medicine and Primary Care, 2015
The array of diagnostic workup for pyrexia of unknown origin (PUO) generally revolves in searching for infections, inflammatory/autoimmune, and endocrine etiologies.
Vikas A Mishra   +2 more
doaj   +1 more source

Valid Presumption of Shiga Toxin-Mediated Damage of Developing Erythrocytes in EHEC-Associated Hemolytic Uremic Syndrome

open access: yesToxins, 2020
The global emergence of clinical diseases caused by enterohemorrhagic Escherichia coli (EHEC) is an issue of great concern. EHEC release Shiga toxins (Stxs) as their key virulence factors, and investigations on the cell-damaging mechanisms toward target ...
Johanna Detzner   +2 more
doaj   +1 more source

Hemolytic anemia

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2014
Summary: Hemolytic anemia is a collection of diseases resulting from an exaggeration of the lysis of red blood cells. Hemolysis can be caused by extravacular aggression by drugs or other toxic or by antibodies againt red blood cell.
JAMILA ELHOUDZI
doaj  

Tegsedi-Induced Warm Antibody Autoimmune Hemolytic Anemia

open access: yesAnnals of Internal Medicine: Clinical Cases
Autoimmune hemolytic anemia is a hemolytic disorder in which antibodies attack erythrocytes, causing their destruction. Many medications have been linked to autoimmune hemolytic anemia, such as antibiotics, chemotherapy agents, and nonsteroidal anti ...
Mariela Di Vanna   +3 more
doaj   +1 more source

Ceftriaxone-induced hemolytic anemia with severe renal failure: a case report and review of literature

open access: yesBMC Pharmacology and Toxicology, 2018
Background Drug induced immune hemolytic anemia (DIIHA) is a rare complication and often underdiagnosed. DIIHA is frequently associated with a bad outcome, including organ failure and even death. For the last decades, ceftriaxone has been one of the most
Hans Benno Leicht   +5 more
doaj   +1 more source

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