Results 81 to 90 of about 16,441 (215)
Objective To evaluate the prognostic utility of circulating interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in patients with Still disease (SD) receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan +8 more
wiley +1 more source
A Case of Hemophagocytic Syndrome due to Tuberculosis: Uncommon Manifestation of a Common Disease
Hemophagocytic syndrome, also known as hemophagocytic lymphohistiocytosis (HLH), is the manifestation of immune dysregulation. It is associated with ineffective but exaggerated immune response and infiltration of active lymphocytes and histiocytes in ...
Arijit Singha +3 more
doaj +1 more source
Severe Thrombocytopenia With Wet Purpura in Brucellosis: A Case Report
ABSTRACT Brucellosis is a zoonotic infection that passes to humans from infected animals via direct contact or the intake of raw milk and its products. The hematologic profile most frequently seen in acute brucellosis includes mild anemia and leukopenia. Severe form of thrombocytopenia and multiple wet purpura over the tongue and buccal mucosa are less
Fatemeh Ravanbakhsh Ghavghani +2 more
wiley +1 more source
Hemophagocytic syndrome in acute respiratory viral infections
This review presents the definition, classification, characteristics of the pathogenesis, diagnostic criteria and description of clinical observations not known to general practitioners hemophagocytic syndrome, which may complicate the severity of acute ...
M. V. Shipilov
core +1 more source
Unusual acute lupus hemophagocytic syndrome – a test of diagnostic criteria: a case report
Background Hemophagocytic lymphohistiocytosis is an aggressive life-threatening syndrome of excessive immune activation. Hemophagocytic lymphohistiocytosis due to systemic lupus erythematosus is described as acute lupus hemophagocytic syndrome.
Wijetunga Mudalige Udai Akalanka Wijetunga +3 more
doaj +1 more source
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra +7 more
wiley +1 more source
Comparison of HScore (A) and the probability of having hemophagocytic syndrome (B) in patients with KFD with and without MAS. HScore, hemophagocytic syndrome score; KFD, Kikuchi-Fujimoto disease; MAS, macrophage activation syndrome.
Dam Kim (3517184) +8 more
core +1 more source
Hematological Oncology, Volume 44, Issue 4, July 2026.
Gianluca Cavallaro +12 more
wiley +1 more source
Epstein-Barr virus (EBV) infection can cause secondary hemophagocytic syndrome and severe chronic active disease. The diseases are characterized by pathologic hyperergic reaction manifested by fever, cytopenia, and multiple organ failure.
Vsevolod Gennadevich Potapenko +1 more
doaj +1 more source
Introduction Hemophagocytic lymphohistiocytosis is an immune-mediated syndrome that typically has a rapidly progressive course that can result in pancytopenia, coagulopathy, multi-system organ failure and death.
Chan Kathryn +4 more
doaj +1 more source

