Results 121 to 130 of about 83,381 (315)
PROTHROMBIN IN ENZYMOLOGY, THROMBOSIS AND HEMOPHILIA [PDF]
G. I. C. Ingram
openalex +1 more source
The Mirage of Factor Equivalence: Examining the Complexities of Non‐Factor Therapies in Haemophilia
ABSTRACT Background This article provides a critical analysis of the ‘factor equivalence’ concept as applied to non‐factor therapies (NFTs) for haemophilia, highlighting its limitations and clinical implications. Although factor equivalence estimates serve as a comparative tool for evaluating pro‐coagulant effects across different therapies, they may ...
Yesim Dargaud +2 more
wiley +1 more source
INDUCTION OF TOLERANCE BY ORAL ADMINISTRATION OF FACTOR VIII AND TREATMENT OF HEMOPHILA [PDF]
Disclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a Subject a therapeutically effective amount of the deficient anti gen, wherein the antigen is not present in a liposome.
Alpan, Oral +3 more
core +1 more source
Measurement of the Effectiveness of (AHG) Therapy in Hemophilia [PDF]
J A Penner
openalex +1 more source
The UK Infected Blood Inquiry: A Personal Reflection
Haemophilia, EarlyView.
Peter R. Foster
wiley +1 more source
ABSTRACT Introduction Haemophilia A and B are hereditary bleeding disorders that require multidisciplinary perioperative management. Data on orthopaedic surgery outcomes with extended‐half‐life (EHL) recombinant Fc‐fusion factor VIII (rFVIIIFc) and factor IX (rFIXFc) products remain limited.
Luigi Piero Solimeno +10 more
wiley +1 more source
F8 Variants and Inhibitor Development in a Multiethnic Cohort of Nonsevere Haemophilia A
ABSTRACT Background Neutralising antibodies (inhibitors) against factor VIII can result in severe bleeding in persons with nonsevere haemophilia A (NSHA). The INSIGHT study of 1112 persons with NSHA in a predominantly White population identified 19 different F8 missense variants that were associated with inhibitor development. Objective To describe the
Ming Y. Lim +3 more
wiley +1 more source
CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome. [PDF]
Multiple genome-wide studies have identified associations between outcome of human immunodeficiency virus (HIV) infection and polymorphisms in and around the gene encoding the HIV co-receptor CCR5, but the functional basis for the strongest of these ...
Anderson, Stephen K +30 more
core
Defibrination Syndrome Developed after Replacement Therapy with PPSB in a Case of Hemophilia B. [PDF]
Mutsuyoshi Kazama +4 more
openalex +1 more source

