Results 121 to 130 of about 68,267 (269)

Patient and parent preferences for characteristics of prophylactic treatment in hemophilia

Patient Preference and Adherence, 2015
Roberto Furlan,1 Sangeeta Krishnan,2 Jeffrey Vietri3 1Advanced Methods, Kantar Health, Epsom, Surrey, UK; 2Global Health Economics and Outcomes Research, Biogen, MA, USA; 3Health Outcomes, Kantar Health, Milan, Italy Introduction: New longer-acting ...
Furlan R, Krishnan S, Vietri J
doaj  

Real‐World Use of Emicizumab in Patients With Acquired Haemophilia A: An Interim Safety Analysis of a Large‐Scale Post‑Marketing Surveillance Study

Haemophilia, EarlyView.
ABSTRACT Introduction Acquired haemophilia A (AHA) is a rare autoimmune disorder where the development of autoantibodies to factor (F)VIII neutralise its function, leading to bleeding. Emicizumab has been approved for treating AHA in Japan. Aim This post‐marketing study was performed to primarily examine the use and safety of emicizumab, and indirectly
Midori Shima, Katsuyuki Fukutake, Yoshiyuki Ogawa, Yuta Kamei, Chiaki Sugita, Akinori Yuri, Ryota Kobayashi, Akiko Ioka, Tadashi Matsushita   +8 more
wiley   +1 more source

Investigator‐Led Research to Improve the Diagnostic Assessment of Platelet Function Disorders: Reflections on the Challenges and Rewards

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley   +1 more source

Postpartum Acquired Hemophilia A in Two Women With Previously Undiagnosed Carrier Status for von Willebrand Disease Type 2N and Heterozygous p.R854Q Mutation

Haemophilia, EarlyView.
Maria Weise, Tristan Klöter, Maren Keller, Sirak Petros, Christian Pfrepper   +4 more
wiley   +1 more source

Representation, medical examination, and the effectiveness of underwriting: Evidence from a life and health insurance company

Risk Management and Insurance Review, EarlyView.
Abstract This study examines whether underwriting methods—representation, medical examination, extra premiums, and coverage—effectively mitigate adverse selection using data from an insurance company. Regarding representation, we focus on statements disclosing pre‐existing medical conditions.
Chia‐Ling Ho, Gene Lai, Chen‐Hsu Liao, Zifen Zeng   +3 more
wiley   +1 more source

CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022)

Bleeding, Thrombosis and Vascular Biology
Background and Aims: Intracerebral hemorrhage (ICH) is a severe and life-threatening complication in patients with hemophilia, often resulting in high mortality and long-term neurological impairment.
doaj   +1 more source

Cryoprecipitate utilisation, shortages and institutional policies in the United States: A survey of practices and policies

Transfusion Medicine, EarlyView.
Abstract Background Since the COVID‐19 pandemic, demand for blood products has remained high, while donations have declined. Institutional policies guiding the use of these products may affect their availability, utilisation and waste. We surveyed blood banks (BBs) in the United States (U.S.) to assess policies and practices related to cryoprecipitate ...
Chinelo P. Onyenekwu, Mariam Ratiani, Jenna Wade, Angela Treml   +3 more
wiley   +1 more source

Prevalence of Hemophilia and Clinicodemographic Characteristics of Hemophilic Patients Aged ≤ 18 Years in Thi-Qar, Iraq

Global Pediatric Health
Objectives . This study aims to determine the prevalence of hemophilia in Thi-Qar, Iraq and study clinical and demographic characteristics of patients with hemophilia. Methods .
Ghada Mansoor Abood FICMS, Raid Kareem Dehiol FICMS, Hayfaa Mohammed Mones FIBMS   +2 more
doaj   +1 more source

Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy

Transfusion, EarlyView.
Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna, Gael B. Morrow, Gang Xu, Lewis Timms, Naveed Akbar, Michael Laffan, Robin P. Choudhury, Nicola Curry   +7 more
wiley   +1 more source

The impact of rapid infusers on the hemostatic potential of cryoprecipitate products

Transfusion, EarlyView.
Abstract Background In cases of massive transfusion, intravenous access can be limited. Additionally, delivering different products through separate lines and infusion methods adds unnecessary steps. RBC, plasma, and whole blood (WB) are delivered via rapid infusers; cryoprecipitate (CRYO) is infused through separate access and is not approved with ...
Connor D. Purvis, Samantha Redden, Andrew Jacobson, Yao‐Wei Wang, Julie Campbell, Jessica Cardenas, Jan‐Michael Van Gent, Bryan A. Cotton   +7 more
wiley   +1 more source