Survival of 125iodine-labeled Factor VIII in normals and patients with classic hemophilia. Observations on the heterogeneity of human Factor VIII. [PDF]
J Over+6 more
openalex +1 more source
The Roles and Clinical Significance of Major Hepatic‐Derived Metabolites in Hepatocellular Carcinoma
ABSTRACT Hepatocellular carcinoma (HCC) is increasingly recognized as a metabolically orchestrated malignancy, in which hepatic‐derived metabolites function not only as byproducts of liver physiology but also as active modulators of tumor biology.
Rui Sun+5 more
wiley +1 more source
Expression and Linkage of Genes for X-linked Hemophilias A and B in the Dog [PDF]
K. M. Brinkhous+3 more
openalex +1 more source
VOLKMANNʼS ISCHEMIC CONTRACTURE IN HEMOPHILIA
Rogers Lee Hill, Barney Brooks
openalex +2 more sources
Characterization and management of patients with hereditary factor X deficiency: A case series
Abstract Background Hereditary factor X deficiency (HFXD) is an ultra‐rare, autosomal recessive bleeding disorder that results in reduced factor X coagulant activity (FX:C). HFXD is traditionally classified by severity as severe (FX:C <1%), moderate (FX:C = 1%–5%), or mild (FX:C = 6%–10%).
Meera Chitlur+4 more
wiley +1 more source
The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B
: Data are needed on minimal factor activity (FA) levels required to prevent bleeding in hemophilia. We aimed to evaluate associations between hemophilia type and FA level and joint bleeding and orthopedic procedures using longitudinal data.
J. Michael Soucie+4 more
doaj
Abstract Plasma‐derived medicinal products (PDMPs), particularly immunoglobulins (Igs), are essential treatments for numerous diseases, often serving as the primary therapeutic option and playing a critical role in patient care. The human origin of these products, however, can lead to supply constraints due to a lack of plasma collection, market ...
Miriam Belmonte+4 more
wiley +1 more source
Pennsylvania state-wide hemophilia program: summary of immediate reactions with the use of factor VIII and factor IX concentrate [PDF]
David Prager+8 more
openalex +1 more source
Techno‐Economic Analysis of Membrane‐Based Purification Platforms for AAV Vector Production
ABSTRACT Technologies for large‐scale manufacturing of viral vectors for gene therapies, such as tangential flow filtration and membrane chromatography, are under development. In these early stages of process development, techno‐economic analyses are useful for identifying membrane properties yielding the greatest impact on process performance. In this
Juan J. Romero+6 more
wiley +1 more source