Results 131 to 140 of about 82,032 (316)

Clinical Features And Laboratory Patterns In A Cohort Of Consecutive Argentinian Patients With Von Willebrand's Disease [PDF]

, 2001
Background and Objectives. von Willebrand's disease (vWD) is a bleeding disorder with variable clinical expression. Our aim was to classify patients with vWD and to determine the phenotype in their relatives. Design and Methods.
Blanco, A. N., Farias, Cristina Elena, Kempfer, Ana Catalina, Lazzari, María Ángela, Meschengieser, S. S., Salviu, M. J., Woods, Adriana Inés   +6 more
core  

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Functional evaluation of joint in moderate to severe hemophilia patients treated with on-demand factor replacement: insights from a single hemophilia treatment center in Bangladesh

The Egyptian Journal of Internal Medicine
Background Hemophilia patients are prone to spontaneous or post-traumatic bleeding, particularly in joints and various other body sites. The high incidence of joint hemorrhages in hemophilia patients underscores the importance of routine joint ...
Sujan Ghosh, Sanzina Sadia Tory, Humayra Nazneen, Nurul Farhad, Salwa Islam, Mohammad Jahid Hasan, Akhil Ranjan Biswas   +6 more
doaj   +1 more source

Hemophilia is associated with accelerated biological aging

Haematologica
Hemophilia is a rare X-linked bleeding disorder caused by mutations in the F8 or F9 gene (hemophilia A or B), leading to deficient factor VIII or IX proteins, respectively.
Marina Trappl, Rafaela Vostatek, Manuel Salzmann, Daniel Kraemmer, Johanna Gebhart, Philipp Hohensinner, Ingrid Pabinger, Cihan Ay   +7 more
doaj   +1 more source

Impact of mild to severe hemophilia on education and work by US men, women, and caregivers of children with hemophilia B: The Bridging Hemophilia B Experiences, Results and Opportunities into Solutions (B‐HERO‐S) study [PDF]

, 2017
Susan Cutter, Don Molter, Spencer Dunn, Susan S. Hunter, Skye Peltier, Kimberly Haugstad, Neil Frick, Natalia Holot, David L. Cooper   +8 more
openalex   +1 more source

Final Analysis of the Phase 1/2 Trial of Valoctocogene Roxaparvovec for Severe Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Valoctocogene roxaparvovec is an adeno‐associated virus vector serotype 5 (AAV5)‐mediated gene therapy for severe haemophilia A (HA). Aim Report the final safety and efficacy results of the phase 1/2 trial of valoctocogene roxaparvovec. Methods An open‐label phase 1/2 trial (NCT02576795) enrolled adult males with severe HA (factor
Priyanka Raheja, Savita Rangarajan, Will Lester, Bella Madan, Glenn F. Pierce, Emily Symington, Carolyn Millar, Dane Osmond, Mingjin Li, Konstantia‐Maria Chavele   +9 more
wiley   +1 more source

Evaluation of Safety and Efficacy of Emicizumab Prophylaxis in Egyptian Pediatric Patients with Hemophilia A

Turkish Journal of Hematology
Objective: Hemophilia A (HA) is a hereditary X-linked bleeding disorder secondary to deficiency of the clotting factor VIII (FVIII). Emicizumab is a monoclonal antibody that replaces the function of the activated FVIII and prevents bleeding in HA ...
Tamer Hassan, Marwa Zakaria, Manar Fathy, Ahmed Farag, Eman Abdelhady, Dalia Gameil, Mustafa Abu Hashem   +6 more
doaj   +1 more source

Management of hydrocephalus in infants with severe hemophilia A: report of 2 cases [PDF]

, 2018
Stephen M. Bergin, Amy L. Dunn, Luke Smith, Annie Drapeau   +3 more
openalex   +1 more source

Positioning of non-factor replacement therapy in the hemophilia treatment

, 2022
Michio Sakai
openalex   +2 more sources

Hemophilia A [PDF]

The Biomedical & Life Sciences Collection, 2020
  +4 more sources