Results 151 to 160 of about 118,583,499 (297)

Challenges in Hemophilia Care and Requirements for Pediatric-to-Adult Transition: Single-Center Experience from a Resource-Limited Setting. [PDF]

Patient Prefer Adherence
Sirachainan N, Kempka K, Tiengtrakulthong A, Chantrathammachart P, Angchaisuksiri P, Chuansumrit A.   +5 more
europepmc   +1 more source

Population Pharmacokinetics of Plasma‑Derived Factor X Using Clotting and Chromogenic Assays: A WAPPS‑Hemo Model

Haemophilia, EarlyView.
ABSTRACT Background Hereditary factor X (FX) deficiency is a rare autosomal recessive bleeding disorder for which individualized pharmacokinetic (PK) assessment can support optimized prophylactic management. The WAPPS‐Hemo platform enables population pharmacokinetic (PopPK) individualized PK predictions based on sparse sampling.
Dagmar M. Hajducek, Pierre Chelle, Manuela Scarpellini, Andrea Edginton, Alfonso Iorio   +4 more
wiley   +1 more source

Canadian emicizumab registry: a blueprint for the future. [PDF]

Blood Adv
Hermans C.
europepmc   +1 more source

Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson, Roy Khalife, Kelsey Uminski   +2 more
wiley   +1 more source

Of mice and FVIIIa mimetics: new hemophilia A models for in vivo evaluation. [PDF]

Blood Adv
Samelson-Jones BJ, Leyes Porello SE.
europepmc   +1 more source

100 Years of von Willebrand Disease (VWD): Comparison of Historical and Contemporary von Willebrand Factor (VWF) Activity Assays in the Laboratory Identification of VWD

Haemophilia, EarlyView.
Abstract Introduction von Willebrand disease (VWD) is a prevalent bleeding disorder resulting from deficiencies and/or defects in von Willebrand factor (VWF). Accurately diagnosing VWD, particularly distinguishing between qualitative defects (types 2A, 2B, 2 M, and 2N) and quantitative defects (types 1 and 3), poses challenges that have significant ...
Emmanuel J. Favaloro, Sandya Arunachalam, Mahzuza Salwa, Ronny Vong, Leonardo Pasalic   +4 more
wiley   +1 more source

Feasibility and perceptions among hemophilia patients and doctors towards ultrasound for the assessment of subclinical abnormalities in hemophilic joints. [PDF]

Medicine (Baltimore)
Ye M, Zhou H, Zhao Y, Chen R, Gao H, Gao S, Yang L, Li Y, Zeng X, Chen C, Zhou Y.   +10 more
europepmc   +1 more source

Ultrasound Versus Magnetic Resonance Imaging for Haemophilic Arthropathy: A Systematic Review With Meta‐Analysis of Diagnostic Accuracy Across Joint Pathologies

Haemophilia, EarlyView.
ABSTRACT Introduction Haemophilic arthropathy (HA) is a debilitating consequence of recurrent intra‐articular bleeding. While magnetic resonance imaging (MRI) is the established gold standard for joint assessment, musculoskeletal ultrasound (US) has emerged as a point‐of‐care alternative.
George Triantafyllou, Konstantina Bolou, Aikaterini Michalopoulou, Athina Dettoraki, Nikolaos‐Achilleas Arkoudis, Maria Piagkou, Olympia Papakonstantinou, Helen Pergantou   +7 more
wiley   +1 more source

Toward Value-Based Reimbursement for Hemophilia A in the UAE: A Multi-Stakeholder Perspective. [PDF]

J Mark Access Health Policy
Al Dallal S, Abuieda H, AlZain N, Farouq Q, Raman S, Mahmoud S, Al Naeem W, Osman A.   +7 more
europepmc   +1 more source

Radiosynoviorthesis in People With Haemophilia—Pain‐Related and Clinical Outcomes: A Prospective Controlled Cohort Study

Haemophilia, EarlyView.
ABSTRACT Introduction Radiosynoviorthesis (RSO) may alleviate pain and clinical symptoms in people with haemophilia (PwH), however, controlled longitudinal data on these outcomes remain limited. Aim To evaluate the effects of RSO on pain, joint health, swelling, and treatment satisfaction over twelve months. Methods Patients with an indication for RSO (
Alexander Schmidt, Pia Möllers, Jamil Hmida, Marius Brühl, Barbara Boddenberg‐Pätzold, Hermann Eichler, Georg Goldmann, Björn Habermann, Susan Halimeh, Johannes Oldenburg, Heinrich Richter, Fabian Tomschi, Andreas C. Strauss, Thomas Hilberg   +13 more
wiley   +1 more source