Results 1 to 10 of about 2,171,591 (317)
Structural and Functional Basis of JAMM Deubiquitinating Enzymes in Disease
Biomolecules, 2022 Deubiquitinating enzymes (DUBs) are a group of proteases that are important for maintaining cell homeostasis by regulating the balance between ubiquitination and deubiquitination.
Xin Pan +5 more
doaj +1 more source
Criticality in EAP Education in Iran: a missing link [PDF]
Journal of English Language Teaching and Learning, 2022 Despite its importance, a review of the related literature reveals not many studies have examined criticality in EAP. Accordingly, in the present study, whether critical approaches were followed in Iranian EAP classes were investigated among EAP teachers
Hassan Soodmand Afshar, Shadi Donyaie
doaj +1 more source
Harnessing Protein-Ligand Interaction Fingerprints to Predict New Scaffolds of RIPK1 Inhibitors
Molecules, 2022 Necroptosis has emerged as an exciting target in oncological, inflammatory, neurodegenerative, and autoimmune diseases, in addition to acute ischemic injuries.
Natália Aniceto +6 more
doaj +1 more source
p38 MAPK inhibitors, IKK2 inhibitors, and TNFα inhibitors in COPD [PDF]
Current Opinion in Pharmacology, 2012 COPD represents a major respiratory disorder, causing significant morbidity and mortality throughout the world. While therapies exist for COPD, they are not always effective, and many patients experience exacerbations and morbidity despite current therapies.
Audreesh, Banerjee +2 more
openaire +2 more sources
Corrosion inhibitors for basic environments [PDF]
, 2021 Nowadays, corrosion control of metals, whose area of use is increasing day by day, has technical, economic, and environmental importance. The most preferred of the various methods used to prevent corrosion is the addition of a suitable inhibitor to the ...
Yıldız, Mehmet +3 more
core +3 more sources
Cryo-electron Microscopy Structure and Transport Mechanism of a Wall Teichoic Acid ABC Transporter
mBio, 2020 The wall teichoic acid (WTA) is a major cell wall component of Gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), a common cause of fatal clinical infections in humans. Thus, the indispensable ABC transporter TarGH, which
Li Chen +11 more
doaj +1 more source
Molecules, 2022 Cancer is a multifactorial disorder caused by several aberrations in gene expression that generate a homeostatic imbalance between cell division and death [...]
Alessandra Ammazzalorso +1 more
openaire +3 more sources
Materials Research Express, 2023 The prevalence of catastrophic structural member failure caused by steel corrosion in civil infrastructure underscores the importance of reducing reinforcement corrosion to enhance overall infrastructure costs, reliability, and sustainable development ...
Smrithy Subash +3 more
doaj +1 more source
Frontiers in Immunology, 2020 Hemophilia A is a genetic disorder that results in the deficiency of functional factor VIII protein, which plays a key role in blood coagulation. Currently, the majority of hemophilia A patients are treated with repeated infusions of factor VIII protein.
Alex C. Chen +5 more
doaj +1 more source
Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
Frontiers in Oncology, 2022 Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA and its derivatives have been used for many centuries due to their natural healing and medicinal properties.
Manzar Alam +8 more
doaj +1 more source