Results 111 to 120 of about 31,863 (238)

A Phase I/II Study of Ibrutinib Plus Trastuzumab in HER2‐Positive Metastatic Breast Cancer

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Ibrutinib has demonstrated inhibition of ErbB/HER tyrosine kinases in preclinical models. This Phase I/II study investigated the safety, efficacy, and immunomodulatory effects of ibrutinib in combination with trastuzumab in patients with HER2‐positive metastatic breast cancer (MBC) whose disease had progressed on ado‐trastuzumab emtansine ...
Joyce O'Shaughnessy, Andrea Glidden, Tracy Locke, Amy Scales, Elizabeth Gatewood, Jean‐Philippe Blanck, Jessica Castaneda‐Gill, Sharlin Patel, Yolanda D. Mahnke, Xuan Wang, Page Blas   +10 more
wiley   +1 more source

Stereotactic electroencephalogram lead placement in patient with hemophilia B: illustrative case. [PDF]

J Neurosurg Case Lessons
Lee GA, Giermasz A, Kanth KM, Abrute V, Brandman DM.   +4 more
europepmc   +1 more source

Sustained Effectiveness of Lanadelumab in Preventing Hereditary Angioedema Attacks: The ENABLE Study

Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.
ABSTRACT Background Lanadelumab has been approved for hereditary angioedema (HAE) long‐term prophylaxis since 2018. The Phase 4, prospective ENABLE Study (NCT04130191) evaluated the long‐term effectiveness and safety of lanadelumab in clinical practice across Europe and the Middle East.
Andrea Zanichelli, Walter A. Wuillemin, Markus Magerl, Andreas Recke, Mauro Cancian, Emel Aygören‐Pürsün, Ramón Lleonart Bellfill, Aharon Kessel, Tamar Kinaciyan, Robin Lochbaum, Mona Al‐Ahmad, Irmgard Andresen, Maureen Watt, Natalie Khutoryansky, Daniel N. Castaner, Inmaculada Martinez‐Saguer   +15 more
wiley   +1 more source

The impact of whole lung irradiation in lung metastatic rhabdomyosarcoma: A pooled analysis of two European trials and one European registry

Cancer, Volume 132, Issue 15, 1 August 2026.
ABSTRACT Background Lung metastases in patients with metastatic rhabdomyosarcoma (RMS) have not been treated uniformly across Europe. This provides comparison of the impact of whole lung irradiation (WLI). Methods Lung‐metastatic patients included in the Cooperative Weichteilsarkom Studiengruppe‐IV 2002, European Pediatric Soft Tissue Sarcoma Study ...
Amadeus T. Heinz, Philip Heesen, Johannes H. M. Merks, Véronique Minard‐Colin, Martin Ebinger, Alison L. Cameron, Semi Harrabi, Henry Mandeville, Reineke A. Schoot, Jörg Fuchs, Gabriela Guillen, Ewa Koscielniak, Julia C. Chisholm, Monika Sparber‐Sauer, Gianni Bisogno   +14 more
wiley   +1 more source

Effect of marstacimab in young people living with severe hemophilia A or moderate to severe hemophilia B without inhibitors: A plain language summary from the BASIS study. [PDF]

Ther Adv Hematol
Patel P.
europepmc   +1 more source

Redefining the role of the transfusion medicine physician in the era of advanced cellular therapies

Transfusion, EarlyView.
Eric A. Gehrie, Kevin J. Land
wiley   +1 more source

Open‐Label, Balanced, Randomized, Single‐Dose, Three‐Treatment, Three‐Sequence, Three‐Period, Three‐Way Crossover Oral Bioequivalence Study of Desmopressin Acetate Oral Solution

Clinical Pharmacology in Drug Development, Volume 15, Issue 8, August 2026.
ABSTRACT Desmopressin is first‐line therapy for central diabetes insipidus, also known as arginine vasopressin deficiency, but presents dosing challenges due to its narrow therapeutic index. This open‐label, randomized, three‐way crossover study evaluated the bioequivalence of a new desmopressin acetate oral solution (50 mcg/mL) compared to ...
Adam Christensen, Axay Parth, Mansi Kotak, Danka Radosavjevic, Catherine Gorman Moore, Byung‐Woun Seo   +5 more
wiley   +1 more source

Cross-cultural validation and reliability of the Korean version of the Haemophilia Activities List. [PDF]

Blood Res
Kim SE, Shim YJ, Yoon HJ, Park SK, Yoo KY, Choi EJ, Kim JY.   +6 more
europepmc   +1 more source

Development of an ultrasound‐guided fascia iliaca compartment block programme for hip fracture analgesia in the accident and emergency department: A model from north lantau hospital

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background Patients with hip fracture presenting at accident and emergency department (AED) of North Lantau Hospital (NLTH) require transfer to a tertiary centre, and the repeated bed transfers involved are painful to the patients. Ultrasound‐guided fascia iliaca compartment block (FICB) is a regional anaesthetic technique for effective opioid‐
Man Ting Lau, Tin Man Hui, Oi Fung Wong, Shing Ko, Wai Ling Irene Lo, Kin Fai Khu, Sing Hing Choi, Yee Ngor Tsui, Yuen Sum Wong   +8 more
wiley   +1 more source

Hemophilia in the Era of Advanced Therapies: Structural Monitoring, the Role of Musculoskeletal Ultrasound, and a Proposed Multidisciplinary Care Model-A Structured Narrative Review. [PDF]

Diagnostics (Basel)
Querol-Giner F, Querol-Giner M, Pérez-Alenda S, Querol-Fuentes F.   +3 more
europepmc   +1 more source