Results 91 to 100 of about 82,032 (316)

A homozygous female hemophilia A

Indian Journal of Human Genetics, 2012
Hemophilia A (HA), being an X-linked recessive disorder, females are rarely affected, although they can be carriers.To study the mutation in F8 gene in an extended family with a homozygous female HA.All the seven affected members (six males and one female) were initially screened by Conformation Sensitive Gel Electrophoresis (CSGE) and direct DNA ...
Nair, Preethi S., Shetty, S., Ghosh, Kanjaksha   +2 more
openaire   +3 more sources

A Psychometric Analysis of the Haemophilia Quality of Life Questionnaire for Adults Physical Health Subscale and Total Scores: Data From the Phase 3 XTEND‐1 Trial in Patients With Severe Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Bleeding episodes can impair physical functioning and cause chronic pain in haemophilia A. The Haemophilia Quality of Life Questionnaire for Adults (Haem‐A‐QoL) was administered in XTEND‐1; the Physical Health (PH) subscale evaluated Physical Health/Functioning. Aim To evaluate psychometric properties of Haem‐A‐QoL PH and estimate
Jérôme Msihid, Alfonso Iorio, Amanda Wilson, Nana Kragh, Lauren Nelson, Shanshan Qin, Annemieke Willemze   +6 more
wiley   +1 more source

Prosthesis survival situation and complications following total hip arthroplasty in hemophilic patients: a systematic review

BMC Musculoskeletal Disorders
Background Hemophilic arthropathy, resulting from recurrent joint bleeding in patients with hemophilia, often necessitates total hip arthroplasty (THA) to alleviate pain and improve joint function.
Lei Chen, Shineng Lin, Wenlu Zhou, Yiqing Ling, Zhenyu Shi, Qinwen Ge, Wenbin Liu, Ju Li, Peijian Tong, Huihui Li, Taotao Xu   +10 more
doaj   +1 more source

Nonneutralizing antibodies in Nordic persons with moderate hemophilia A and B (the MoHem study)

Research and Practice in Thrombosis and Haemostasis
Background: The impact of nonneutralizing antibodies (NNAs) in moderate hemophilia is elusive. Objectives: To explore the presence of NNAs in Nordic persons with moderate hemophilia A (MHA) and B (MHB) in relation to treatment modality, clinical outcome,
Ragnhild J. Måseide, MD, PhD, Erik Berntorp, MD, PhD, Jan Astermark, MD, PhD, Anna Olsson, MD, PhD, Maria Bruzelius, MD, PhD, Tony Frisk, MD, PhD, Vuokko Nummi, MD, PhD, Riitta Lassila, MD, PhD, Karin Strandberg, MD, PhD, Geir E. Tjønnfjord, MD, PhD, Pål A. Holme, MD, PhD   +10 more
doaj   +1 more source

Geographic differences in hemophilia-associated AIDS incidence in Pennsylvania. By the Pennsylvania AIDS Surveillance Study Group [PDF]

, 1987

openalex   +1 more source

High-levelexpression of functional recombinant human coagulation factor VII in insect cells [PDF]

: Recombinant coagulation factor VII (FVII) is used as a potential therapeutic intervention in hemophilia patients who produce antibodies against the coagulation factors.
AD Shapiro, Ali Jahanian Najafabadi, Amaneh Mohammadi Roushandeh, B Brenner, B Furie, BG Maick, CR Hay, DA Roth, DE Lynn, DR O’Reilly, G Bray, G Kemball-Cook, HJ Cha, I Nillson, KR Kim, Mahdi Edalati Fathabad, Mahdi Rouhbakhsh, Mahshid Mohammadipour, Mehryar Habibi Roudkenar, MK Miller, Mohamad Ali Shokrgozar, Mohamad Salimi, N Wajih, Nasser Masroori, R Halabian, R Toso, Raheleh Halabian, SM Ruiz, SM Wu, T Li, UK Laemmli   +30 more
core   +1 more source

Predicting Recovery After Joint Bleeding in Persons With Bleeding Disorders

Haemophilia, EarlyView.
ABSTRACT Introduction Joint bleeds are burdensome and recovery differs from bleed to bleed. Identifying predictors of recovery could enable personalized treatment and monitoring; aiming to prevent long‐term joint deterioration, and facilitate faster return to activities. Aim To identify predictors of time to recovery after joint bleeding in people with
Gijs Aertssen, Lize F. D. van Vulpen, Wouter Foppen, Flora H. P. van Leeuwen, Merel A. Timmer   +4 more
wiley   +1 more source

Strategies for Hemophilia Treatment, a literature review of current evidence

مجله دانشگاه علوم پزشکی بیرجند, 2023
Hemophilia is an inherited bleeding disorder caused by malfunctioning or lacking blood coagulation factor VIII (hemophilia A) or IX (hemophilia B). Currently, the main treatments for these X-linked diseases are replacement therapy using periodic and ...
Fahimeh Ghasemi, Nafiseh Erfanian, Samira Karbasi, Alireza Zomorodipour   +3 more
doaj  

Association of inferior vena cava filter placement for venous thromboembolic disease and a contraindication to anticoagulation with 30-day mortality [PDF]

, 2018
Importance: Despite the absence of data from randomized clinical trials, professional societies recommend inferior vena cava (IVC) filters for patients with venous thromboembolic disease (VTE) and a contraindication to anticoagulation therapy.
Brown, David L, Novak, Eric, Saeed, Mohammed J, Turner, Tyson E   +3 more
core   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source