Results 121 to 130 of about 118,583,499 (297)

Concomitant Use of rFVIIa and Emicizumab in People with Hemophilia A with Inhibitors: Current Perspectives and Emerging Clinical Evidence

open access: yesTherapeutics and Clinical Risk Management, 2020
Silvia Linari, Giancarlo Castaman Department of Oncology, Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Florence, ItalyCorrespondence: Giancarlo CastamanDepartment of Oncology, Center for Bleeding Disorders and Coagulation ...
Linari S, Castaman G
doaj  

Acquired hemophilia A

open access: yesHematology, 2006
Acquired hemophilia A is a rare but severe autoimmune bleeding disorder, resulting from the presence of autoantibodies directed against clotting factor VIII. The etiology of the disorder remains obscure, although approximately half of all cases are associated with other underlying conditions.
openaire   +2 more sources

The Burden of Prior Authorizations in Bleeding Disorder Specialty Drugs

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Prior authorizations (PAs) are widely used to control healthcare costs and ensure appropriate use of high‐cost therapies, but they often create undue administrative burdens. In haemophilia care, timely access to specialty medications is critical, yet Haemophilia Treatment Centres (HTCs) must frequently navigate payer‐driven PA ...
Lisa Littner   +3 more
wiley   +1 more source

Identification of people with acquired hemophilia in a large electronic health record database

open access: yes, 2017
Michael Wang,1 Anissa Cyhaniuk,2 David L Cooper,3 Neeraj N Iyer3 1Hemophilia and Thrombosis Center, University of Colorado School of Medicine, Aurora, CO, 2AC Analytic Solutions, Barrington, IL, 3Clinical Development, Medical and Regulatory Affairs, Novo
Wang M, Iyer NN, Cyhaniuk A, Cooper DL
core  

The Haemophilia Health Journey: Experiences and Unmet Care Needs of Caregivers and Their Young Children

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Understanding patients’ and caregivers’ experiences, values and needs is essential to implement patient‐centred care. However, specific insights into how young children with haemophilia and their caregivers experience the entire care trajectory, from diagnosis onwards, remain limited.
Caroline M. A. Mussert   +11 more
wiley   +1 more source

Barriers and perceived limitations to early treatment of hemophilia

open access: yes, 2013
Kapil Saxena Boston Hemophilia Center, Boston Children’s Hospital, Boston, MA, USA Abstract: Early treatment of bleeds in hemophilia patients, both with and without inhibitors, has been shown to be of immense benefit in the overall clinical outcome.
Saxena K
core  

Rituximab for managing acquired hemophilia A in a case of chronic neutrophilic leukemia with the JAK2 kinase V617F mutation

open access: yes, 2012
Shinsaku Imashuku,1 Naoko Kudo,1 Kagekatsu Kubo,1 Katsuyasu Saigo,1 Nanako Okuno,2 Kaoru Tohyama21Division of Hematology, Takasago-seibu Hospital, Takasago, Japan; 2Department of Laboratory Medicine, Kawasaki Medical School, Kurashiki, JapanBackground ...
Tohyama K   +5 more
core  

Population‐Level Real‐World Healthcare Costs in Men and Women With Haemophilia A

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Even with modern prophylaxis options, people living with haemophilia have significantly lower quality of life and joint health outcomes than those without. Aim Our goal was to determine if real‐world health‐system costs are higher for people living with haemophilia A compared to those without and determine how joint‐health state ...
Sam Hirniak   +6 more
wiley   +1 more source

DDAVP Challenges in 170 Children With von Willebrand Disease: Response Classification Varies According to Criteria Used

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Individuals diagnosed with types 1/1C/2A/2M von Willebrand disease (VWD) typically undergo a desmopressin (DDAVP) challenge to assess therapeutic benefit. This involves measuring von Willebrand factor antigen (VWF:Ag), activity (VWF:Act; VWF:RCo/VWF:GPIbM/VWF:Ab), and coagulant factor VIII (FVIII:C) levels 0 (pre), 1, and 4‐h post‐
Michael Shu   +7 more
wiley   +1 more source

Global Diagnostics of Hemophilia and Bleeding Disorders: Insights From World Federation of Hemophilia International External Quality Assessment Scheme Program 2016–2023

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Accurate laboratory diagnosis is essential for the effective management of bleeding disorders. The World Federation of Hemophilia (WFH) International External Quality Assessment Scheme (IEQAS) provides an international platform for comparative evaluation of laboratory performance.
Silmara de Lima Montalvão   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy