Results 121 to 130 of about 31,863 (238)
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta +2 more
wiley +1 more source
Management of bleeds in people living with hemophilia A or B without inhibitors and receiving marstacimab: A plain language summary of publication from the BASIS study. [PDF]
Kim HK.
europepmc +1 more source
ABSTRACT Background Acquired hemophilia A (AHA) is a rare autoimmune bleeding disorder requiring prompt hemostatic control and sustained prevention of rebleeding. Recombinant porcine factor VIII (rpFVIII, susoctocog alfa) controls acute bleeding, while emicizumab provides prophylaxis. Real‐world data on their sequential use are limited.
Yusuke Yamada +2 more
wiley +1 more source
[Impact of effective health information acquisition on hemophilia-related health literacy among caregivers of underage hemophilia patients]. [PDF]
Yuan R +6 more
europepmc +1 more source
ABSTRACT Background Real‐world data on low‐dose emicizumab in young children with hemophilia A are limited. Methods This multicenter retrospective study included 26 children (median age: 2.2 years) receiving individualized low‐dose emicizumab (2019–2025).
Guichi Zhou +9 more
wiley +1 more source
Occult Hemophilia B and Plastic Surgery: Preventing Bleeding Events. [PDF]
Cárdenas-Camarena L +2 more
europepmc +1 more source
ABSTRACT Introduction Patients with haemophilia (PWH) undergoing invasive procedures are at increased risk of periprocedural bleeding, and optimal haemostatic response (HR) depends on patient‐ and procedure‐related factors. We aimed to evaluate variables associated with HR in PWH undergoing invasive procedures.
Jose Antonio Sanchez Salas +3 more
wiley +1 more source
Long-term effect of marstacimab on joints that bleed frequently in people living with severe hemophilia without inhibitors: A plain language summary of publication. [PDF]
Kim HK.
europepmc +1 more source

