Results 231 to 240 of about 22,643,381 (355)

Prevalence and Clinical Correlation of Intron 22 Inversion in Hemophilia A in Northeast India. [PDF]

Cureus
Barman R, Sarma A, Ahmed Z, Dutta A.
europepmc   +1 more source

IQ Survey Results on Current Industry Practices: Part 2—Quantitative Evaluations of Immunogenicity Assessment

Clinical Pharmacology &Therapeutics, Volume 117, Issue 6, Page 1605-1613, June 2025.
All biotherapeutics have the potential to induce an immunogenic response and generate anti‐drug antibodies (ADAs), especially when administered as multiple doses over prolonged periods. However, a clinically meaningful effect of ADAs can be difficult to identify to communicate the impact of immunogenicity on drug exposure, safety and efficacy outcomes ...
Susan Richards, Insa Winzenborg, Doreen Luedtke, Tao Niu, Lora Hamuro, Karey Kowalski, Jocelyn H. Leu, Jianning Yang, Vaishnavi Ganti, Indranil Bhattacharya, Ivelina Gueorguieva, Nael Mostafa, Christine Grimaldi, Benjamin Wu   +13 more
wiley   +1 more source

Case Report: Severe hemophilia B patient with inhibitor and anaphylaxis reaction to FIX, successfully managed with concizumab prophylaxis therapy. [PDF]

Front Pediatr
Bonetti E, Esposto MP, Zaccaron A, Guardo C, Caddeo G, Chinello M, Balter R, Pezzella V, Vitale V, Cesaro S.   +9 more
europepmc   +1 more source

(6) IMMUNOLOGICAL STUDIES ON HEMOPHILIA A, CARRIERS OF HEMOPHILIA A AND von WILLEBRAND'S DISEASE

, 1975
T. Kamiya, Junzo ISHIGURO, K Koie, Hidehiko SAITO   +3 more
openalex   +2 more sources

Anti-inhibitor Coagulant Complex (Autoplex) for treatment of factor VIII inhibitors in hemophilia [PDF]

, 1980
C F Abildgaard, J. A. Penner, EJ Watson-Williams   +2 more
openalex   +1 more source

New horizons in the pharmacological management of venous thromboembolism

HemaSphere, Volume 9, Issue 6, June 2025.
Abstract Many patients suffer from venous thromboembolism (VTE) and its consequences. Despite substantial advancements with the introduction of direct oral anticoagulants (DOACs), patients and clinicians still encounter challenges in the acute and long‐term management of VTE, such as recurrent events, anticoagulant‐related bleeding complications, and ...
Andreas Verstraete, Quentin Van Thillo, Thomas Vanassche, Peter Verhamme   +3 more
wiley   +1 more source

Hemophilia B With Intracranial Hemorrhage Rehabilitation in High-Dependency Unit: A Case Report. [PDF]

Clin Case Rep
Feng X, Zhu H, Han L, Xu H, He L.
europepmc   +1 more source

Isolation and characterization of a human T cell leukemia virus type II from a hemophilia-A patient with pancytopenia. [PDF]

, 1985
V. S. Kalyanaraman, R.B. Narayanan, Paul Feorino, R Ramsey, E.L. Palmer, Terence Chorba, Sarah J McDougal, Jane P. Getchell, Brian P. Holloway, A. Harrison   +9 more
openalex   +1 more source

Nonsense Mutations in Rare and Ultra‐Rare Human Disorders: An Overview

IUBMB Life, Volume 77, Issue 6, June 2025.
ABSTRACT Over 7000 rare diseases have been described, collectively affecting 350 million people worldwide. Most of these conditions result from nonsense mutations, representing approximately 10% of all genetic mutations associated with human inherited diseases.
Emanuele Vitale, Davide Ricci, Federica Corrao, Ignazio Fiduccia, Ilenia Cruciata, Pietro Salvatore Carollo, Alessio Branchini, Laura Lentini, Ivana Pibiri   +8 more
wiley   +1 more source

Life-Threatening Pharyngolaryngeal Hematoma in a Patient With Hemophilia A. [PDF]

Cureus
Yanagihara K, Mochizuki Y, Katsube A, Kamio T, Akiyama M.   +4 more
europepmc   +1 more source