Results 1 to 10 of about 301,593 (214)
The odds and implications of coinheritance of hemophilia A and B [PDF]
Research and Practice in Thrombosis and Haemostasis, 2020 We report 2 patients with coinheritance of the X‐linked bleeding disorders hemophilia A and hemophilia B. We describe the family pedigrees, clinical features, and genotyping.
Corinne Karch +7 more
doaj +4 more sources
Carrier Detection in Hemophilia B. [PDF]
Thrombosis and Haemostasis, 1977 We examined 37 obligatory carriers of hemophilia B and 40 normal women. The levels of both factor IX activity and factor IX antigen were determined. The factor IX antigen levels were assayed in an inhibitor neutralization test in which a rabbit antiserum was used.
E Briët +3 more
openalex +2 more sources
A Case of Acquired Hemophilia A and Congenital Hemophilia B. [PDF]
Cureus, 2022 Congenital hemophilia B is a rare, inherited X-linked bleeding disorder caused by a deficiency of factor IX (FIX). Acquired hemophilia A is a rare, acquired bleeding disorder which presents as new onset bleeding in older adults due to the development of autoantibodies against factor VIII (FVIII).
Fortier JC +4 more
europepmc +2 more sources
Total Hip Arthroplasty for Avascular Necrosis in a Patient With Hemophilia B. [PDF]
Arthroplast TodayAvascular necrosis (AVN) of the femoral head accounts for up to 10% of all total hip arthroplasties performed annually. Typically associated with intravascular coagulation, AVN is extremely rare in patients with bleeding disorders such as hemophilia B ...
Dandamudi S +4 more
europepmc +2 more sources
The frequency of complications in a cohort of patients diagnosed with hemophilia A and hemophilia B receiving prophylactic treatment in Colombia: A retrospective noninterventional study. [PDF]
PLoS One, 2023 IntroductionHemophilia A and B are disorders associated with the deficit of coagulation factors VIII and IX.ObjectiveWas to determine the incidence of complications in a cohort of patients diagnosed with moderate and severe hemophilia A or B under ...
Machado Alba JE +9 more
europepmc +2 more sources
Hemophilia B in a Crossbred Maltese Dog
Journal of Veterinary Medical Science, 2006 A crossbred Maltese dog, 6-year-old, male, was presented to us for examination due to coagulopathy. On examination of blood coagulation screening tests, activated partial thromboplastin time (APTT) was markedly prolonged (63.6 sec). Therefore, a defect in the intrinsic pathway of coagulation was suspected. An additional serum test was also examined and
Makoto Nakata, Manabu Sakai, Takeo Sakai
openalex +5 more sources
BMC Health Services Research, 2022 Background Hemophilia care in mainland China has been greatly improved since the establishment of the Hemophilia Treatment Center Collaborative Network of China (HTCCNC), and most of drugs for hemophilia have been covered by basic medical insurance ...
Zhengwei Huang +6 more
doaj +1 more source
Managing Relevant Clinical Conditions of Hemophilia A/B Patients
Hematology Reports, 2023 The Medical Directors of nine Italian Hemophilia Centers reviewed and discussed the key issues concerning the replacement therapy of hemophilia patients during a one-day consensus conference held in Rome one year ago. Particular attention was paid to the
Massimo Morfini +9 more
doaj +1 more source
Seroprevalence to adeno‐associated virus type 6 in people with hemophilia B from a UK adult cohort
Research and Practice in Thrombosis and Haemostasis, 2022 Background Gene therapy shows promise as a potential “cure” for hemophilia A and B. Adeno‐associated virus (AAV) vectors are the leading platform to deliver modified genetic code of factor VIII or IX to the liver effecting endogenous production.
Sara Boyce +9 more
doaj +1 more source
Haematologica, 2020 Hemophilia B is an X-linked recessive bleeding disorder caused by abnormalities in the coagulation factor IX gene. Without prophylactic treatment, patients experience frequent spontaneous bleeding episodes.
Jiahuan Chen +14 more
doaj +1 more source