Results 61 to 70 of about 884,735 (335)

Clinical Management of Postpartum Hemorrhage in Community Birthing Hospitals in Vermont: A Gap Analysis to Promote Best Practice [PDF]

, 2020
Purpose: Despite advances in research and medical technology, the rates of postpartum hemorrhage (PPH) continue to rise. Annually, these preventable events are the cause of one-fourth of maternal deaths worldwide.
Greene, Rachel
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Minimal long-term neurobehavioral impairments after endovascular perforation subarachnoid hemorrhage in mice [PDF]

, 2017
Cognitive deficits are among the most severe and pervasive consequences of aneurysmal subarachnoid hemorrhage (SAH). A critical step in developing therapies targeting such outcomes is the characterization of experimentally-tractable pre-clinical models ...
Brody, David L, Fanizzi, Claudia, Gangolli, Mihika, Kummer, Terrance T, Sauerbeck, Andrew D, Zipfel, Gregory J   +5 more
core   +2 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Genetic polymorphisms associated with upper gastrointestinal bleeding: A systematic review protocol

Revista de Ciências Farmacêuticas Básica e Aplicada, 2020
Gastrointestinal bleedings (GIB) are one of the most frequent adverse drug reactions.  Among the GIB upper gastrointestinal bleeding (UGIB) stands out due to their high mortality.
Marcela Forgerini, Rosa C. Lucchetta, Patricia de Carvalho Mastroianni   +2 more
doaj  

Subarachnoid Hemorrhage from Posterior Cerebral Artery Aneurysm during Puerperium – Case Report and Review of Literature [PDF]

, 2012
Subarachnoid hemorrhages (SAH) due to true aneurysms of the Posterior Cerebral Artery (PCA) during puerperium in young and healthy females are extremely rare.
Brawanski, Alexander, Mark, Karl-Heinz, Rennert, Janine, Schebesch, Karl-Michael, Schödel, Petra   +4 more
core   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Isolated Gastric Varix Bleeding Caused by Splenic Vein Obstruction: Two Case Reports

Journal of the Korean Society of Radiology, 2023
Isolated left-sided portal hypertension is a rare clinical syndrome caused by splenic veno-occlusive disease. Splenic vein thrombosis and extrinsic compression causes proximal splenic vein hypertension, and the splenic blood flows into the superior ...
Juyoung Pak, Sangjoon Lee, Hyoung Nam Lee, Dongho Hyun, Sung-Joon Park, Youngjong Cho   +5 more
doaj   +1 more source

Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]

, 2014
Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas, Jung, Grace, Kautz, Léon, Nemeth, Elizabeta, Rivella, Stefano, Valore, Erika V   +5 more
core   +1 more source

Primary intracerebral hemorrhage and subarachnoid hemorrhage

Journal of Stroke and Cerebrovascular Diseases, 1999
Intracerebral hemorrhage (ICH) constitutes about 13% of stroke cases in the United States. I In Asian populations, the frequency may be as high as 30% of all strokes. 2 The United States age-adjusted incidence of ICH is 10 to 15 per 100,000 per year and doubles with each decade after age 45.
Issam A. Awad, Anthony J. Furlan, Saleem I. Abdulrauf   +2 more
openaire   +3 more sources