Results 41 to 50 of about 1,399,338 (302)

Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC [PDF]

open access: yes, 2011
Background: Oral anticoagulant therapy (OAT) with warfarin is the standard of stroke prevention in patients with atrial fibrillation. Approximately 30% of patients with cardioembolic strokes are on OAT at the time of symptom onset.
Förch, Christian   +14 more
core   +2 more sources

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Treatment of Hemorrhagic Disorders [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1969
Since there have been at least ten other books on bleeding and coagulation disorders published in the 60's, one might well ask, "Why another?" Several answers are forthcoming: (1) Some facets of specific therapy, such as the use of cryoprecipitated antihemophilic factor in classic hemophilia, the use of heparin in defibrination syndromes, and the use ...
  +4 more sources

Management of heavy menstrual bleeding in a multidisciplinary young women’s clinic: a Dutch experience

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Heavy menstrual bleeding (HMB) is common in young women. It may lead to iron deficiency with or without anemia, decreased school, work, sport, and social participation, and may be the first sign of underlying bleeding disorders (BDs ...
Yara Dixon   +6 more
doaj   +1 more source

Adverse reaction signals mining and hemorrhagic signals comparison of ticagrelor and clopidogrel: A pharmacovigilance study based on FAERS

open access: yesFrontiers in Pharmacology, 2022
Background: Ticagrelor and clopidogrel are commonly used antiplatelet agents, and we conducted a pharmacovigilance analysis using the Food and Drug Administration Adverse Event Reporting System (FAERS) to provide a reference for safe and reasonable ...
Shu Tang   +4 more
doaj   +1 more source

Ischaemic strokes in patients with pulmonary arteriovenous malformations and hereditary hemorrhagic telangiectasia: associations with iron deficiency and platelets. [PDF]

open access: yes, 2014
25/03/14 meb. OA paper , Ok to add.Background: Pulmonary first pass filtration of particles marginally exceeding ~7 µm (the size of a red blood cell) is used routinely in diagnostics, and allows cellular aggregates forming or entering the circulation in ...
John A Livesey   +38 more
core   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

The evolving landscape of gene therapy for congenital severe hemophilia: a 2024 state of the art

open access: yesBleeding, Thrombosis and Vascular Biology
Despite major advances in prophylaxis, no repeated dosing regimen with currently employed extended-half-life or non-factor products replaces the advantages of a long-term cure in persons with severe congenital hemophilia A and B (HA, HB).
Giovanni Di Minno   +8 more
doaj   +1 more source

Extrapyramidal movement disorders in patients after stroke

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Presented are the clinical spectrum and the frequency of mainforms of extrapyramidal movement disorders in patients afterischemic or hemorrhagic stroke.
N. V. Pizova
doaj   +1 more source

Nutritional Supplementation of Naturally Occurring Vitamin D to Improve Hemorrhagic Stroke Outcomes

open access: yesFrontiers in Neurology, 2021
Vitamin D deficiency, if left untreated, is associated with bone disorders, cardiovascular damage, and an increased risk of ischemic stroke. While there are various nutritional options for the natural intake of vitamin D, we hope to elucidate the ...
Rani Ashouri   +6 more
doaj   +1 more source

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