Results 41 to 50 of about 82,627 (300)

The evolving landscape of gene therapy for congenital severe hemophilia: a 2024 state of the art

Bleeding, Thrombosis and Vascular Biology
Despite major advances in prophylaxis, no repeated dosing regimen with currently employed extended-half-life or non-factor products replaces the advantages of a long-term cure in persons with severe congenital hemophilia A and B (HA, HB).
Giovanni Di Minno, Gaia Spadarella, Ilenia Lorenza Calcaterra, Giancarlo Castaman, Paolo Simioni, Raimondo De Cristofaro, Cristina Santoro, Flora Peyvandi, Matteo Di Minno   +8 more
doaj   +1 more source

Extrapyramidal movement disorders in patients after stroke

Анналы клинической и экспериментальной неврологии, 2017
Presented are the clinical spectrum and the frequency of mainforms of extrapyramidal movement disorders in patients afterischemic or hemorrhagic stroke.
N. V. Pizova
doaj   +1 more source

Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions.

, 2008
The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease-approaching 90% in many outbreaks.
Bausch, D G, A.G. Sprecher, Paul Boumandouki, Boumandouki, P, Daniel G. Bausch, Jeffs, B, Benjamin Jeffs, Sprecher, A G   +7 more
core   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Treatment of Hemorrhagic Disorders. [PDF]

Annals of Internal Medicine, 1969
Since there have been at least ten other books on bleeding and coagulation disorders published in the 60's, one might well ask, "Why another?" Several answers are forthcoming: (1) Some facets of specific therapy, such as the use of cryoprecipitated antihemophilic factor in classic hemophilia, the use of heparin in defibrination syndromes, and the use ...
  +4 more sources

Angina Bullosa Hemorrhagica: A Rare Case Involving the Ventral Tongue

Clinical Case Reports
Angina bullosa hemorrhagica (ABH) is a rare benign condition characterized by the sudden onset of hemorrhagic blisters in the oral mucosa, often triggered by minor trauma.
Fatemeh Khajehzadeh
doaj   +1 more source

Local Experimental Intracerebral Hemorrhage in Rats

Biomedicines, 2021
(1) Background: Hemorrhagic stroke is a lethal disease, accounting for 15% of all stroke cases. However, there are very few models of stroke with a hemorrhagic etiology. Research work is devoted to studying the development of cerebrovascular disorders in
Ekaterina Vasilevskaya, Aleksandr Makarenko, Galina Tolmacheva, Irina Chernukha, Anastasiya Kibitkina, Liliya Fedulova   +5 more
doaj   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Retrospective analysis on clinical characteristics and venous thromboembolism outcomes using bridging prophylaxis with low molecular weight heparin for thrombophilic women performing oocyte retrieval for assisted reproductive procedures: 15 years of experience

Italian Journal of Medicine
In vitro fertilization (IVF) procedures have been frequently associated with antithrombotic treatment, particularly aspirin or low molecular weight heparin.
Pierpaolo Di Micco, Corrado Lodigiani, Lidia Luciana Rota, Giuseppe Camporese, Ida Strina, Carlo Alviggi   +5 more
doaj   +1 more source

Dynamic Process of Secondary Pulmonary Infection in Mice With Intracerebral Hemorrhage

Frontiers in Immunology, 2021
Stroke is a common central nervous system disease in clinical practice. Stroke patients often have infectious complications, such as pneumonia and infections of the urinary tract and gastrointestinal tract.
Hanyu Zhang, Hanyu Zhang, Yingying Huang, Yingying Huang, Yingying Huang, Xiaojin Li, Xiaojin Li, Xu Han, Xu Han, Jing Hu, Jing Hu, Bin Wang, Bin Wang, Lin Zhang, Lin Zhang, Pengwei Zhuang, Pengwei Zhuang, Yanjun Zhang, Yanjun Zhang   +18 more
doaj   +1 more source