Results 61 to 70 of about 80,797 (257)

THE ROLE OF BLEEDING HISTORY AND CLINICAL MARKERS FOR THE CORRECT DIAGNOSIS OF VWD

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2013
Quantification of the bleeding severity by use of bleeding assessment tools (BAT) and bleeding score (BS) has been consistently shown to improve the clinical diagnosis of von Willebrand disease (VWD) while helping researchers establish phenotype/genotype
Alberto Tosetto
doaj   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

open access: yesAdvanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang   +12 more
wiley   +1 more source

EPIDEMIOLOGY OF STROKE IN THE GISSAR REGION OF TAJIKISTAN

open access: yesПаёми Сино, 2019
Objective: To study the epidemiological features of stroke in the Gissar region of Tajikistan. Methods: This study was carried out between 2015 and 2016 at the Gissar Central District Hospital, where inpatient treatment was carried out for patients ...
M.T. GANIEVA   +2 more
doaj   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

open access: yesAdvanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown   +3 more
wiley   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung   +19 more
wiley   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

open access: yesAdvanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He   +10 more
wiley   +1 more source

Vitamin K-dependent coagulopathy in neonatological and pediatric practice: controversial issues and clinical analysis [PDF]

open access: yesРМЖ. Мать и дитя
A.L. Zaplatnikov1,2, A.V. Dmitriev1,3, B.D. Babaev1, A.A. Dement'ev1, Zh.L. Chabaidze1, I.D. Maikova2, M.V. Leshik1, D.N. Smirnov1 1Russian Medical Academy of Continuous Professional Education, Moscow,   Russian Federation 2Z.A ...
A.L. Zaplatnikov   +7 more
doaj  

A rare case of post-operative bleeding in cataract surgery – An eye opener

open access: yesIndian Journal of Ophthalmology. Case Reports
Ocular surgery in patients with bleeding disorders is challenging due to the high risk of hemorrhagic complications. This case report of a patient with chronic decompensated liver disease, who presented with incessant postoperative bleeding, served as a ...
Meera B Rahim   +5 more
doaj   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

open access: yesAdvanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang   +11 more
wiley   +1 more source

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