Results 41 to 50 of about 952,590 (241)

Synergistic anti-SARS-CoV-2 activity of repurposed anti-parasitic drug combinations

BMC Pharmacology and Toxicology, 2022
Background COVID-19 pandemic has claimed millions of lives and devastated the health service system, livelihood, and economy in many countries worldwide.
Kunlakanya Jitobaom, Chompunuch Boonarkart, Suwimon Manopwisedjaroen, Nuntaya Punyadee, Suparerk Borwornpinyo, Arunee Thitithanyanont, Panisadee Avirutnan, Prasert Auewarakul   +7 more
doaj   +1 more source

Risk factors associated with sustained circulation of six zoonotic arboviruses: a systematic review for selection of surveillance sites in non-endemic areas

Parasites & Vectors, 2019
Arboviruses represent a significant burden to public health and local economies due to their ability to cause unpredictable and widespread epidemics. To maximize early detection of arbovirus emergence in non-endemic areas, surveillance efforts should ...
Helen J. Esser, Ramona Mögling, Natalie B. Cleton, Henk van der Jeugd, Hein Sprong, Arjan Stroo, Marion P. G. Koopmans, Willem F. de Boer, Chantal B. E. M. Reusken   +8 more
doaj   +1 more source

Hemorrhagic Fever with Renal Syndrome, Russia

Emerging Infectious Diseases, 2019
In Russia, 131,590 cases of hemorrhagic fever with renal syndrome caused by 6 different hantaviruses were reported during 2000–2017. Most cases, 98.4%, were reported in western Russia.
E. Tkachenko, A. Ishmukhametov, T. Dzagurova, A. Bernshtein, V. G. Morozov, A. Siniugina, S. Kurashova, A. Balkina, P. Tkachenko, D. Kruger, B. Klempa   +10 more
semanticscholar   +1 more source

Crimean-Congo Hemorrhagic Fever [PDF]

Journal of Special Operations Medicine, 2015
In mid-September 2009, a 22-year-old critically ill Soldier was medically evacuated from a treatment facility in southern Afghanistan to Landstuhl Regional Medical Center in Germany. Despite the efforts of the team at Landstuhl, this patient died and became the US military's first known victim of Crimean-Congo hemorrhagic fever (CCHF).
Sara, Shayan, Mohammad, Bokaean, Mona Ranjvar, Shahrivar, Sadegh, Chinikar   +3 more
openaire   +4 more sources

Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever

Scientific Reports, 2019
Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-borne bunyavirus, can cause a life-threatening hemorrhagic syndrome in humans but not in its animal host.
Sergio E. Rodriguez, R. Cross, Karla A. Fenton, D. Bente, C. Mire, T. Geisbert   +5 more
semanticscholar   +1 more source

Evaluation of biochemical and haematological changes in dengue fever and dengue hemorrhagic fever in Sri Lankan children: a prospective follow up study

BMC Pediatrics, 2019
BackgroundSeries of biochemical and haematological changes occur during the course of dengue infection, which vary depending on the clinical disease. The patterns of change are not well documented and identifying these patterns in children with dengue ...
Grace Angeline Malarnangai Kularatnam, E. Jasinge, S. Gunasena, D. Samaranayake, M. Senanayake, V. Wickramasinghe   +5 more
semanticscholar   +1 more source

Dengue virus NS1 secretion is regulated via importin-subunit β1 controlling expression of the chaperone GRp78 and targeted by the clinical drug ivermectin

mBio, 2023
Dengue virus (DENV) is a major human pathogen. An important pathogenicity factor is non-structural protein 1 (NS1) required for viral replication and secreted from infected cells.
Solène Denolly, Hongbo Guo, Miriam Martens, Anna Płaszczyca, Pietro Scaturro, Vibhu Prasad, Kessiri Kongmanas, Nuntaya Punyadee, Adisak Songjaeng, Dumrong Mairiang, Andreas Pichlmair, Panisadee Avirutnan, Ralf Bartenschlager   +12 more
doaj   +1 more source

Recent advances in understanding Crimean–Congo hemorrhagic fever virus

F1000Research, 2018
Crimean-Congo hemorrhagic fever virus (CCHFV) is a widely distributed hemorrhagic fever virus and the cause of hemorrhagic disease in Africa, Southern and Eastern Europe, the Middle East, India and Asia.
David W. Hawman, H. Feldmann
semanticscholar   +1 more source

Prospective forecasts of annual dengue hemorrhagic fever incidence in Thailand, 2010–2014

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Dengue hemorrhagic fever poses a major problem for public health officials in Thailand. The number and location of cases vary dramatically from year to year, which makes planning prevention and treatment activities before the dengue season ...
S. Lauer, K. Sakrejda, E. Ray, L. Keegan, Qifang Bi, P. Suangtho, S. Hinjoy, S. Iamsirithaworn, S. Suthachana, Yongjua Laosiritaworn, D. Cummings, J. Lessler, N. Reich   +12 more
semanticscholar   +1 more source

Unmasking the role of mast cells in dengue

eLife, 2013
Immune cells called mast cells can hinder rather than help the body's response to dengue virus, which suggests that mast cell products could be used as biomarkers to identify severe forms of the disease.
Panisadee Avirutnan, Ponpan Matangkasombut   +1 more
doaj   +1 more source