Results 21 to 30 of about 59,728 (193)

Vasopressors: Do they have any role in hemorrhagic shock?

Journal of Anaesthesiology Clinical Pharmacology, 2017
The priority in the management of patients with traumatic hemorrhagic shock is to control the bleeding with simultaneous volume resuscitation to maintain adequate tissue perfusion.
Babita Gupta, Neha Garg, Rashmi Ramachandran   +2 more
doaj   +1 more source

Protective effect of pericytes against vascular leakage in rats with hemorrhagic shock

Di-san junyi daxue xuebao, 2020
Objective To investigate the protective effect of pericytes (PCs) against vascular leakage in rats with hemorrhagic shock. Methods Sixty-four 12- to 24-week-old SD rats weighing 200~220 g were randomized equally into sham-operated group, hemorrhagic ...
HE Shuangshuang, ZHU Yu, ZHOU Henan, WANG Hongchen, LI Tao, LIU Liangming   +5 more
doaj   +1 more source

Hydrogen sulfide in posthemorrhagic shock mesenteric lymph drainage alleviates kidney injury in rats [PDF]

Brazilian Journal of Medical and Biological Research, 2015
Posthemorrhagic shock mesenteric lymph (PHSML) is a key factor in multiple organ injury following hemorrhagic shock. We investigated the role of hydrogen sulfide (H2S) in PHSML drainage in alleviating acute kidney injury (AKI) by administering D,L ...
B. Han, Z.G. Zhao, L.M. Zhang, S.G. Li, C.Y. Niu   +4 more
doaj   +3 more sources

Recruitment of neutrophils across the blood-brain barrier: the role of posttraumatic hepatic ischemia [PDF]

Acta Cirúrgica Brasileira, 2003
PURPOSE: To study the effects of total hepatic ischemia, and reperfusion on the accumulation of neutrophils in the brain of rats submitted to normovolemic conditions as well as to controlled hemorrhagic shock state.
Mario Mantovani, Mauro José Fontelles, Elcio Shiyoiti Hirano, Rosana Celestina Morandin, André Almeida Schenka   +4 more
doaj   +1 more source

Oxygen Regime and Exchange of Ammonia in the Sensomotor Cortex of Cats During Blood Loss and Hyperbaric Oxygenation

Общая реаниматология, 2020
Purpose. To study the effect of hyperbaric oxygenation (HBO) on the oxygen regime and ammonia metabolism in the neurons of cat cortex in hemorrhagic shock.Material and methods. Experiments were performed on 164 cats (males).
V. N. Yakovlev, P. N. Savilov
doaj   +1 more source

Impaired Fracture Healing after Hemorrhagic Shock

Mediators of Inflammation, 2015
Impaired fracture healing can occur in severely injured patients with hemorrhagic shock due to decreased soft tissue perfusion after trauma. We investigated the effects of fracture healing in a standardized pressure controlled hemorrhagic shock model in ...
Philipp Lichte, Philipp Kobbe, Roman Pfeifer, Graeme C. Campbell, Rainer Beckmann, Mersedeh Tohidnezhad, Christian Bergmann, Mamed Kadyrov, Horst Fischer, Christian C. Glüer, Frank Hildebrand, Hans-Christoph Pape, Thomas Pufe   +12 more
doaj   +1 more source

The effect of subdiaphragmatic vagotomy on heart rate variability and lung inflammation in rats with severe hemorrhagic shock

BMC Cardiovascular Disorders, 2022
Background The influence of cutting the sub-diaphragmatic branch of the vagus nerve on heart rate variability (HRV) and inflammatory reaction to severe hemorrhagic shock has not been determined prior to this study.
Fateme Khodadadi, Farzaneh Ketabchi, Zahra Khodabandeh, Alireza Tavassoli, Gregory F. Lewis, Aminollah Bahaoddini   +5 more
doaj   +1 more source

Class of hemorrhagic shock is associated with progressive diastolic coronary flow reversal and diminished left ventricular function

Frontiers in Physiology, 2022
Introduction: The relationship between coronary artery flow and left ventricular (LV) function during hemorrhagic shock remains unknown. The aim of this study was to quantify coronary artery flow directionality alongside left ventricular function through
Noha N. Elansary, Noha N. Elansary, David P. Stonko, Rebecca N. Treffalls, Hossam Abdou, Marta J. Madurska, Jonathan J. Morrison   +6 more
doaj   +1 more source

Ursolic acid inhibits superoxide production in activated neutrophils and attenuates trauma-hemorrhage shock-induced organ injury in rats.

PLoS ONE, 2014
Neutrophil activation is associated with the development of organ injury after trauma-hemorrhagic shock. In the present study, ursolic acid inhibited the superoxide anion generation and elastase release in human neutrophils.
Tsong-Long Hwang, Hsin-I Shen, Fu-Chao Liu, Hsin-I Tsai, Yang-Chang Wu, Fang-Rong Chang, Huang-Ping Yu   +6 more
doaj   +1 more source

Centhaquine Restores Renal Blood Flow and Protects Tissue Damage After Hemorrhagic Shock and Renal Ischemia

Frontiers in Pharmacology, 2021
Background: Centhaquine (CQ) (Lyfaquin®) is in late stage clinical development as a safe and effective first-in-class resuscitative agent for hemorrhagic shock patients (NCT02408731, NCT04056065, and NCT04045327). Acute kidney injury (AKI) is known to be
Amaresh K. Ranjan, Zhong Zhang, Seema Briyal, Anil Gulati, Anil Gulati   +4 more
doaj   +1 more source