Diaspirin cross-linked hemoglobin fails to improve left ventricular diastolic function after fluid resuscitation from hemorrhagic shock [PDF]
, 2001 In severe hemorrhagic shock, left ventricular (LV) diastolic dysfunction is an early sign of cardiac failure due to compromised myocardial oxygenation.
Habler, Oliver +4 more
core +1 more source
The effect of p38 mitogen-activated protein kinase activation on inflammatory liver damage following hemorrhagic shock in rats. [PDF]
PLoS ONE, 2012 Hemorrhagic shock is a frequent cause of liver failure and often leads to a fatal outcome. Several studies have revealed that p38 MAPK is a key mediator in hemorrhagic damage of the primary organs through the activation of proinflammatory cytokines such ...
Hiroaki Sato +2 more
doaj +1 more source
The salutary effects of diphenyldifluoroketone EF24 in liver of a rat hemorrhagic shock model [PDF]
, 2015 BACKGROUND: Liver is a target for injury in low flow states and it plays a central role in the progression of systemic failure associated with hemorrhagic shock.
Alamdar Hussain +4 more
core +1 more source
Di-san junyi daxue xuebao, 2020 Objective To explore the relationship between activated dynamin-related protein 1 (Drp1)-mediated mitochondrial function and energy metabolism after hemorrhagic shock and clarify its potential mechanisms.
DUAN Chenyang +4 more
doaj +1 more source
Can we continue research in splenectomized dogs? Mycoplasma haemocanis: Old problem - New insight [PDF]
, 2004 We report the appearance of a Mycoplasma haemocanis infection in laboratory dogs, which has been reported previously, yet, never before in Europe. Outbreak of the disease was triggered by a splenectomy intended to prepare the dogs for a hemorrhagic shock
A. Schropp +35 more
core +1 more source
Vasopressors: Do they have any role in hemorrhagic shock?
Journal of Anaesthesiology Clinical Pharmacology, 2017 The priority in the management of patients with traumatic hemorrhagic shock is to control the bleeding with simultaneous volume resuscitation to maintain adequate tissue perfusion.
Babita Gupta +2 more
doaj +1 more source
Protective effect of pericytes against vascular leakage in rats with hemorrhagic shock
Di-san junyi daxue xuebao, 2020 Objective To investigate the protective effect of pericytes (PCs) against vascular leakage in rats with hemorrhagic shock. Methods Sixty-four 12- to 24-week-old SD rats weighing 200~220 g were randomized equally into sham-operated group, hemorrhagic ...
HE Shuangshuang +5 more
doaj +1 more source
Hydrogen sulfide in posthemorrhagic shock mesenteric lymph drainage alleviates kidney injury in rats [PDF]
Brazilian Journal of Medical and Biological Research, 2015 Posthemorrhagic shock mesenteric lymph (PHSML) is a key factor in multiple organ injury following hemorrhagic shock. We investigated the role of hydrogen sulfide (H2S) in PHSML drainage in alleviating acute kidney injury (AKI) by administering D,L ...
B. Han +4 more
doaj +3 more sources
Recruitment of neutrophils across the blood-brain barrier: the role of posttraumatic hepatic ischemia [PDF]
Acta Cirúrgica Brasileira, 2003 PURPOSE: To study the effects of total hepatic ischemia, and reperfusion on the accumulation of neutrophils in the brain of rats submitted to normovolemic conditions as well as to controlled hemorrhagic shock state.
Mario Mantovani +4 more
doaj +1 more source
Modulation of syndecan-1 shedding after hemorrhagic shock and resuscitation. [PDF]
PLoS ONE, 2011 The early use of fresh frozen plasma as a resuscitative agent after hemorrhagic shock has been associated with improved survival, but the mechanism of protection is unknown.
Ricky J Haywood-Watson +9 more
doaj +1 more source