Results 101 to 110 of about 514,533 (252)

Frequency and determinants for hemorrhagic transformation of posterior cerebral stroke

BMC Research Notes, 2017
Background hemorrhagic transformation is a threatening ischemic stroke complication. Frequency of hemorrhagic transformation differs greatly among studies, and its risk factors have been usually studied in patients with anterior ischemic stroke who ...
Francesca Valentino, Luana Gentile, Valeria Terruso, Sergio Mastrilli, Paolo Aridon, Paolo Ragonese, Caterina Sarno, Giovanni Savettieri, Marco D’Amelio   +8 more
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Does statin increase the risk of intracerebral hemorrhage in stroke survivors? A meta-analysis and trial sequential analysis

Therapeutic Advances in Neurological Disorders, 2019
Background: It remains debatable whether statin increases the risk of intracerebral hemorrhage (ICH) in poststroke patients. Methods: We systematically searched PubMed, EMBASE, and CENTRAL for randomized controlled trials. Trial sequential analysis (TSA)
Ru Jian Jonathan Teoh, Chi-Jung Huang, Chi Peng Chan, Li-Yin Chien, Chih-Ping Chung, Shih-Hsien Sung, Chen-Huan Chen, Chern-En Chiang, Hao-Min Cheng   +8 more
doaj   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Artificial Intelligence-Based Differentiation of Ischemic and Hemorrhagic Stroke: A Retrospective, Analytical and Observational Case-Control Design

Brain Science Advances
Background: Rapid differentiation between ischemic and hemorrhagic stroke is essential because management differs significantly. In settings without immediate neuroimaging, artificial intelligence (AI) may assist early decision-making.
Yvanne Joshua C. Rabe, Monique Therese B. Punsalan, Lindt Camille O. Alba, Charles Matthew B. Talaue   +3 more
doaj   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source

An ecological study of PM2.5 and black carbon and acute hemorrhagic stroke: a long term effect study

Environmental Research Communications
Both PM2.5 and black carbon particle are associated with acute ischemic stroke. There is limited data on the correlation of long term effects of PM2.5 and black carbon on acute hemorrhagic stroke with a large sample size.
Kannikar Kongbunkiat, Pipat Pattanapipitpaisal, Suphasit Seoratanaphunt, Udomlack Peansukwech, Nisa Vorasoot, Narongrit Kasemsap, Somsak Tiamkao, Verajit Chotmongkol, Thanat Nakaphan, Kittisak Sawanyawisuth   +9 more
doaj   +1 more source

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Blood microRNAs as potential diagnostic markers for hemorrhagic stroke

Neural Regeneration Research, 2017
Proper medical treatment of a stroke victim relies on accurate and rapid differentiation between ischemic and hemorrhagic stroke, which in current practice is performed by computerized tomography (CT) or magnetic resonance imaging (MRI) scans. A panel of
Bridget Martinez, Philip V Peplow
doaj   +1 more source

Hyperglycemia and incidence of ischemic and hemorrhagic stroke-comparison between fasting and 2-hour glucose criteria

, 2009
BACKGROUND AND PURPOSE: We examined the impact of hyperglycemia on ischemic and hemorrhagic stroke incidence comparing criteria based on fasting plasma glucose (FPG) and 2-hour plasma glucose (2-hour PG).
Stehouwer, Coen D A, Mähönen, Markku, Qiao, Qing, Tuomilehto, Jaakko, Pyörälä, Kalevi, Zethelius, Björn,, Hyvärinen, Marjukka   +6 more
core   +1 more source