Results 121 to 130 of about 514,533 (252)

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Comparison of Post-Stroke Functional Recovery between Ischemic and Hemorrhagic Stroke Patients: A Prospective Cohort Study

Althea Medical Journal, 2017
pathophysiologic mechanism that underlies each stroke type may give different outcome in post-stroke patients. This study aimed to compare the improvement of functional outcome between both types of stroke among stroke patients admitted to Dr.
Sabrina Anggi Lubis, Novitri Novitri, Ahmad Rizal   +2 more
doaj  

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Early outcomes of thrombolysis for acute ischaemic stroke in a South African tertiary care centre [PDF]

, 2012
Includes abstract.Includes bibliographical references.Stroke is an important cause of death and disability in sub-Saharan Africa. Recombinant tissue plasminogen activator (tPA) thrombolysis is effective in treating acute ischaemic stroke, but may not be ...
Wasserman, Sean
core   +1 more source

Application of readmission ratio adjustment in calculating the incidence rate of stroke in residents of Weifang city: a medical insurance data-based analysis

Zhongguo gonggong weisheng
ObjectiveTo explore the application of readmission ratio adjustment method in calculating the incidence rate of stroke among residents in Weifang city, Shandong province for estimating the first incidence rate of chronic diseases based on medical ...
Jingxin WANG, Fengli CUI, Xianfeng MENG, Wenyi YANG, Yingjuan XU, Limei AI, Xinguo YIN, Ping CHEN, Chunping WANG, Hongqi SHENG, Xia WAN   +10 more
doaj   +1 more source

A Multi‐Scale Computational Framework for Evaluating Wireless Neuromodulation Feasibility via Magnetoelectric Nanoparticles

Advanced Science, EarlyView.
A multiscale computational framework links single‐nanoparticle magnetoelectric behavior to tissue‐level electric field distributions, integrating experimental data from nanoparticle characterization and in vitro stimulation setups. Applied to a cortical slice configuration, the framework predicts optimal MENP concentrations and stimulation parameters ...
Marta Bonato, Elric Zhang, Emma Chiaramello, Serena Fiocchi, Giulia Suarato, Valentin Gantenbein, Nathalia Cancino‐Fuentes, Alejandro Suarez‐Perez, Maria V. Sanchez‐Vives, Salvador Pané, Marta Parazzini   +10 more
wiley   +1 more source

Patient‐Mounted Neuro Optical Coherence Tomography for Targeted Minimally Invasive Micro‐Resolution Volumetric Imaging in Brain In Vivo

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu, Zhiwei Fang, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren, Wu Yuan   +7 more
wiley   +1 more source

Prognostic factors of functional outcome in acute ischemic stroke [PDF]

, 2013
Trombolyse is een behandeling waarbij een stolsel in een bloedvat wordt opgelost door het gebruik van anti-bloedstollingsmiddelen. Irene Miedema deed onderzoek naar veiligheidsaspecten van trombolyse.
Miedema, Irene, Miedema, Irene,
core   +1 more source

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source