Results 51 to 60 of about 4,191 (194)

Impact of Family History of Haemophilia on Diagnosis, Management and Outcomes in Severe Haemophilia

Haemophilia, Volume 31, Issue 4, Page 679-686, July 2025.
ABSTRACT Introduction Patients with severe haemophilia A (HA) with no family history of haemophilia will be diagnosed upon their first bleeding event. Methods Herein, we studied the effects of lack of family history in HA and the subsequent delay of diagnosis on bleeding pattern and early treatment, as well as on the risk of inhibitor development.
Ana Mendoza, Isabel Rivas, Olga Benítez Hidalgo, Ana Rosa Cid, Martin Olivieri, Susanna Ranta, Veerle Labarque, Nadine G. Andersson, Marloes de Kovel, María Teresa Álvarez‐Román   +9 more
wiley   +1 more source

HEMOSTASIA: DESAFIOS NA EDUCAÇÃO DE HEMATOLOGIA

Hematology, Transfusion and Cell Therapy, 2023
Objetivos: Relatar na forma de relato de experiência a participação de alunos monitores na disciplina de Hematologia da UNIRIO no ensino da Hemostasia. Material e métodos: Relato de experência de monitores e o aproveitamento de discentes da aula prática de Hemostasia para os alunos do sétimo período da UNIRIO, como parte de um projeto acadêmico ...
RC Bokehi, LC Figueiredo, NS Sampaio, FRO Lima, CP Batista, MM Meis, LN Veloso, MCG Andreolli, MC Magalhães, VRGA Valviesse   +9 more
openaire   +2 more sources

Efeito da hemodiluição normovolêmica aguda na coagulação sanguínea: comparação entre os testes colhidos de um modelo in vivo e de um modelo in vitro Efecto de la hemodilución normovolémica aguda en la coagulación sanguínea: comparación entre los tests recolectados en un modelo in vivo y en un modelo in vitro Effects of acute normovolemic hemodilution on blood coagulation: comparison between tests of an in vivo and an in vitro model

Revista Brasileira de Anestesiologia, 2010
JUSTIFICATIVA E OBJETIVOS: A hemodiluição normovolêmica produz resultados conflitantes na hemostasia, pois os trabalhos diferem quanto a tipo de líquido utilizado, profundidade da hemodiluição, método utilizado para avaliar a hemostasia e forma de se ...
Marco Aurélio Beloto de Souza, Jyrson Guilherme Klamt, Luís Vicente Garcia   +2 more
doaj   +1 more source

Mieloma Múltiplo e distúrbios da hemostasia [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2007
O mieloma múltiplo (MM) é o tumor de células plasmocitárias que corresponde a aproximadamente 10% das neoplasias hematológicas. Durante o seu curso clínico, relata-se que 15-30% dos pacientes podem apresentar manifestações hemorrágicas, decorrentes de vários mecanismos fisiopatológicos.
D'Amico, Elbio A., Villaça, Paula R.
openaire   +3 more sources

How to explain the beneficial effects of leukocyte‐ and platelet‐rich fibrin

Periodontology 2000, Volume 97, Issue 1, Page 74-94, February 2025.
Abstract The survival of an organism relies on its ability to repair the damage caused by trauma, toxic agents, and inflammation. This process involving cell proliferation and differentiation is driven by several growth factors and is critically dependent on the organization of the extracellular matrix. Since autologous platelet concentrates (APCs) are
Juan Blanco, Angel García, Lidia Hermida‐Nogueira, Ana B. Castro   +3 more
wiley   +1 more source

A phase 1/2 safety and efficacy study of TAK‐754 gene therapy: The challenge of achieving durable factor VIII expression in haemophilia A clinical trials

Haemophilia, Volume 31, Issue 1, Page 108-117, January 2025.
Abstract Introduction Haemophilia A is an X‐linked bleeding disorder resulting from a deficiency of factor VIII (FVIII). To date, multiple gene therapies have entered clinical trials with the goal of providing durable haemostatic protection from a single dose. TAK 754 (BAX 888) is an investigational AAV8‐based gene therapy containing a FVIII transgene.
John Chapin, Maria Teresa Álvarez Román, Mila Ayash‐Rashkovsky, Dorothee Diogo, Jon Kenniston, Francisco‐Jose Lopez‐Jaime, Caterina Maggiore, María‐Eva Mingot‐Castellano, Kavitha Rajavel, Antoine Rauch, Sophie Susen, Marcin von Grotthuss, Matt Wagoner, Qin Wang   +13 more
wiley   +1 more source

Alterações da hemostasia em crianças submetidas a cirurgia cardíaca com circulação extracorpórea [PDF]

Arquivos Brasileiros de Cardiologia, 1998
OBJETIVO: Avaliar as alterações de hemostasia encontradas em crianças submetidas a cirurgia cardíaca com circulação extracorpórea (CEC). MÉTODOS: Estudamos 17 crianças no pré e pós-operatório (PO) imediato, no 1° PO e entre o 4º e 7º PO, analisando o ...
Fernanda Maria Rebouças da Costa Silveira, Dayse Maria Lourenço, Miguel Maluf, Werther B. Carvalho, Enio Buffolo, Antonio Carlos Carvalho   +5 more
doaj   +1 more source

Efficacy and safety of robotic liver surgery for the elderly: A propensity‐score matched analysis of short‐term outcomes with open liver surgery at a single center in Denmark

Journal of Hepato-Biliary-Pancreatic Sciences, Volume 31, Issue 9, Page 625-636, September 2024.
Fukumori and colleagues compared the short‐term results of robotic liver surgery with those of conventional open liver surgery in elderly patients aged 70 years and over and used propensity score‐matched analysis to assess safety and efficacy. Robotic liver surgery can be safely performed in patients aged 70 years and older.
Daisuke Fukumori, Christoph Tschuor, Takashi Hamada, Luit Penninga, Jens Hillingsø, Lars Bo Svendsen, Peter Nørgaard Larsen   +6 more
wiley   +1 more source

Cystathionine β-synthase and methylenetetrahydrofolate reductase mutations in Mexican individuals with hyperhomocysteinemia

SAGE Open Medicine, 2020
Background: Hyperhomocysteinemia, a thrombotic risk factor, may have several causes. Among the genetic causes of hyperhomocysteinemia, there are polymorphisms in the enzymes methylenetetrahydrofolate reductase (C677T) and cystathionine β-synthase (C699T,
Anahi Guadalupe Figueroa-Torres, Lisneth Osiris Matias-Aguilar, Erika Coria-Ramirez, Edmundo Bonilla-Gonzalez, Humberto Gonzalez-Marquez, Isabel Ibarra-Gonzalez, Jose Rubicel Hernandez-Lopez, Jesus Hernandez-Juarez, Victor Manuel Dominguez-Reyes, Irma Isordia-Salas, Abraham Majluf-Cruz   +10 more
doaj   +1 more source

Increased matrix metalloproteinase‐2 in ligamentum flavum hypertrophy and the regulation of MMP‐2/TIMPs by elastin‐derived peptides

Journal of Orthopaedic Research, Volume 42, Issue 9, Page 2061-2071, September 2024.
Abstract The study aimed to examine matrix metalloproteinase‐2 (MMP‐2) expression in a rat ligamentum flavum (LF) hypertrophy model in vivo, and the effect of elastin‐derived peptides (EDPs) on MMP‐2 and tissue inhibitors of metalloproteinases (TIMPs) in rat LF cells in vitro.
Wen‐Hai Zhuo, Hwee Weng Dennis Hey, Wing Moon Raymond Lam, Xiaoyun Chloe Chan, Loo Hoey Lit, Yong Soon Chiong, Hee‐Kit Wong   +6 more
wiley   +1 more source