Results 241 to 250 of about 1,148,530 (304)

Fibrocaps for surgical hemostasis: two randomized, controlled phase II trials

open access: yesJournal of Surgical Research, 2015
Fibrocaps, a ready-to-use, dry-powder fibrin sealant containing human plasma-derived thrombin and fibrinogen, is being developed as an adjunct for surgical hemostasis.Safety and efficacy of Fibrocaps applied directly or by spray device, in combination with gelatin sponge, was compared with that of gelatin sponge-alone in two randomized, single-blind ...
Verhoef, C.   +10 more
openaire   +4 more sources

Surgical hemostasis

Journal of Neurosurgery, 1979
✓ Every surgical procedure taxes the hemostatic defenses of the patient. If his hemostatic mechanism is sound, he is unlikely to have a bleeding problem during or after an operation, unless, of course, a suture or clip slips off. Two classes of patients do present bleeding problems to the surgeon.
C A, Owen, E J, Bowie
openaire   +2 more sources

Achieving Hemostasis in the Surgical Field

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2009
Hemostatic mechanisms are an integral part of the human physiology. Traditionally divided into intrinsic and extrinsic arms, the coagulation cascade converges, through the interactions of many different factors, at a common element—thrombin. As a consequence, a number of different agents have been developed to supplement this common, critical step to ...
Bradley A, Boucher, Oren, Traub
openaire   +2 more sources

Anticoagulation and Hemostasis in Cardiac Surgical Patients

Journal of Cardiac Surgery, 1994
Optimizing anticoagulation and hemostasis during cardiopulmonary bypass and perioperatively helps to ensure the best possible clinical outcome. This article reviews the pharmacology of unfractionated and low-molecular weight heparin, aprotinin, desmopressin, dextran, antiplatelet agents, warfarin, and direct thrombin inhibitors.
N I, Kondo   +3 more
openaire   +2 more sources

Miniclips and microclips for surgical hemostasis

Journal of Neurosurgery, 1986
✓ The authors have designed a miniclip and a microclip for occlusion of small perforating vessels deep in the operative wound. These clips are intended for permanent occlusion but may be used for temporary hemostasis.
T M, Sundt, G, Kees
openaire   +2 more sources

Surgical Bleeding and Hemostasis

2006
An understanding of the processes of hemostasis and thrombosis is necessary for every surgical procedure. There are a large number of biochemical events that occur in response to endothelial injury that result in the formation of a fibrin clot. Clinical bleeding may result from a defect or deficiency in any of these events or from technical error.
Gregory R. Brevetti   +2 more
openaire   +1 more source

Efficacy of hemostatic agents in improving surgical hemostasis

Transfusion Medicine Reviews, 1996
C URTAILING operative bleeding has always been a surgical priority. Perioperative hemorrhage, and the need for blood product transfusions, increases morbidity, mortality, and cost. The driest fields are usually attributed to the most skillful surgeons.
D, Green, C A, Wong, P, Twardowski
openaire   +2 more sources

Fundamentals of Surgical Hemostasis

2018
This chapter highlights methods for the safe management of blood vessels and for the control of bleeding vessels during traditional open operations. The principles described are the basis for mechanical hemostasis in any operation. They are evidence based in the collective experience of a handful of veteran surgeons.
openaire   +1 more source

Hemostasis in the surgical patient.

The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1991
Hemostatic disorders present a challenging problem to the surgeon and patient alike. Many of these disorders are first discovered at the time of planned or emergent surgical procedures. This manuscript will review the normal hemostatic mechanisms and the more common congenital and acquired coagulopathies.
E H, Rareshide, R G, Amedee
openaire   +1 more source

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